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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 29, 1999 - Issue 11
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Original Articles

A Convenient One-Step Gingerol Synthesis

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Pages 1933-1939 | Received 09 Nov 1998, Published online: 17 Sep 2007

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N. Vijendra Kumar, S. C. Santosh Kumar, P. Srinivas & B. K. Bettadaiah. (2015) An Improved Route to the Preparation of 6-, 8-, 10-Gingerols. Organic Preparations and Procedures International 47:6, pages 443-448.
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Articles from other publishers (20)

Samridhi Sharma, Monu Kumar Shukla, Krishan Chander Sharma, Tirath, Lokender Kumar, Jasha Momo H. Anal, Santosh Kumar Upadhyay, Sanjib Bhattacharyya & Deepak Kumar. (2022) Revisiting the therapeutic potential of gingerols against different pharmacological activities. Naunyn-Schmiedeberg's Archives of Pharmacology 396:4, pages 633-647.
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Nantaporn Promdam & Pharkphoom Panichayupakaranant. (2022) [6]-Gingerol: A narrative review of its beneficial effect on human health. Food Chemistry Advances 1, pages 100043.
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Rita Nasti, Ivan Bassanini, Erica Elisa Ferrandi, Federica Linguardo, Susanna Bertuletti, Marta Vanoni, Sergio Riva, Luisella Verotta & Daniela Monti. (2022) Stereoselective Biocatalyzed Reductions of Ginger Active Components Recovered from Industrial Wastes. ChemBioChem 23:8.
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Rodney A. Fernandes, Amit K. Jha & Praveen Kumar. (2020) Recent advances in Wacker oxidation: from conventional to modern variants and applications. Catalysis Science & Technology 10:22, pages 7448-7470.
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Rodney A. Fernandes, Gujjula V. Ramakrishna & Venkati Bethi. (2020) MnO 2 as a terminal oxidant in Wacker oxidation of homoallyl alcohols and terminal olefins . Organic & Biomolecular Chemistry 18:31, pages 6115-6125.
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Yu-Ting Du, Ya-Long Zheng, Yuan Ji, Fang Dai, Yong-Jing Hu & Bo Zhou. (2018) Applying an Electrophilicity-Based Strategy to Develop a Novel Nrf2 Activator Inspired from Dietary [6]-Shogaol. Journal of Agricultural and Food Chemistry 66:30, pages 7983-7994.
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Zhirui Yang, Dingkun Zhang, Yaming Zhang, Mingquan Wu, Honghong Liu, Xue Han, Quanfu Zheng, Yinqiu Huang, Chang Chen, Lu Zhang, Dan Yan, YanLing Zhao & Xiaohe Xiao. (2016) Thermal activities of 6-gingerol, 8-gingerol and 6-shogaol on the potentiation of mitochondria thermogenesis based on microcalorimetry. Journal of Thermal Analysis and Calorimetry 127:2, pages 1787-1795.
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Carola Schoenknecht, Gaby Andersen, Ines Schmidts & Peter Schieberle. (2016) Quantitation of Gingerols in Human Plasma by Newly Developed Stable Isotope Dilution Assays and Assessment of Their Immunomodulatory Potential. Journal of Agricultural and Food Chemistry 64:11, pages 2269-2279.
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Paul M. Ziemba, Benjamin S.P. Schreiner, Caroline Flegel, Robin Herbrechter, Timo D. Stark, Thomas Hofmann, Hanns Hatt, Markus Werner & Günter Gisselmann. (2015) Activation and modulation of recombinantly expressed serotonin receptor type 3A by terpenes and pungent substances. Biochemical and Biophysical Research Communications 467:4, pages 1090-1096.
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Ruchi Badoni Semwal, Deepak Kumar Semwal, Sandra Combrinck & Alvaro M. Viljoen. (2015) Gingerols and shogaols: Important nutraceutical principles from ginger. Phytochemistry 117, pages 554-568.
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A. Ramesh Reddy, Sachin B. Wadavrao, J. S. Yadav & A. Venkat Narsaiah. (2015) An Efficient Enantioselective Synthesis of Natural Gingerols, the Active Principles of Ginger. Helvetica Chimica Acta 98:7, pages 1009-1017.
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S.R. Feroz, S.B. Mohamad, G.S. Lee, S.N.A. Malek & S. Tayyab. (2015) Supramolecular interaction of 6-shogaol, a therapeutic agent of Zingiber officinale with human serum albumin as elucidated by spectroscopic, calorimetric and molecular docking methods. Phytomedicine 22:6, pages 621-630.
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Dong-Liang Lu, Xiu-Zhuang Li, Fang Dai, Yan-Fei Kang, Yan Li, Meng-Meng Ma, Xiao-Rong Ren, Gao-Wei Du, Xiao-Ling Jin & Bo Zhou. (2014) Influence of side chain structure changes on antioxidant potency of the [6]-gingerol related compounds. Food Chemistry 165, pages 191-197.
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Achinto Saha, Jorge Blando, Eric Silver, Linda Beltran, Jonathan Sessler & John DiGiovanni. (2014) 6-Shogaol from Dried Ginger Inhibits Growth of Prostate Cancer Cells Both In Vitro and In Vivo through Inhibition of STAT3 and NF-κB Signaling . Cancer Prevention Research 7:6, pages 627-638.
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Derek A. Jackson & Andrew P. Dicks. (2012) The Five Senses of Christmas Chemistry. Journal of Chemical Education 89:10, pages 1267-1273.
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N. Vijendra Kumar, P. Srinivas & B.K. Bettadaiah. (2012) New scalable and eco-friendly synthesis of gingerols. Tetrahedron Letters 53:24, pages 2993-2995.
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Shichao Ma, Shilei Zhang, Wenhu Duan & Wei Wang. (2009) An enantioselective synthesis of (+)-(S)-[n]-gingerols via the l-proline-catalyzed aldol reaction. Bioorganic & Medicinal Chemistry Letters 19:14, pages 3909-3911.
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Yasuka Isa, Yuri Miyakawa, Masayoshi Yanagisawa, Tsuyoshi Goto, Min-Sook Kang, Teruo Kawada, Yasujiro Morimitsu, Kikue Kubota & Takanori Tsuda. (2008) 6-Shogaol and 6-gingerol, the pungent of ginger, inhibit TNF-α mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes. Biochemical and Biophysical Research Communications 373:3, pages 429-434.
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C. Ficker, M. L. Smith, K. Akpagana, M. Gbeassor, J. Zhang, T. Durst, R. Assabgui & J. T. Arnason. (2003) Bioassay‐guided isolation and identification of antifungal compounds from ginger. Phytotherapy Research 17:8, pages 897-902.
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Steven A. Fleming, Carrie W. Dyer & Julie Eggington. (2010) ChemInform Abstract: A Convenient One‐Step Gingerol Synthesis.. ChemInform 30:32.
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