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Review Article

Responsiveness, behavioural arousal and awareness in fetal and newborn lambs: experimental, practical and therapeutic implications

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Pages 2-13 | Accepted 21 Jul 2002, Published online: 22 Feb 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

G Stilwell, DJ Mellor & SE Holdsworth. (2020) Potential benefit of a thoracic squeeze technique in two newborn calves delivered by caesarean section. New Zealand Veterinary Journal 68:1, pages 65-68.
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DJ Mellor & TJ Diesch. (2007) Birth and hatching: Key events in the onset of awareness in the lamb and chick. New Zealand Veterinary Journal 55:2, pages 51-60.
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Leena Anil, Sukumarannair S. Anil & John Deen. (2005) Pain Detection and Amelioration in Animals on the Farm: Issues and Options. Journal of Applied Animal Welfare Science 8:4, pages 261-278.
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Articles from other publishers (49)

Yvette Nout‐Lomas. 2024. Equine Neonatal Medicine. Equine Neonatal Medicine 712 723 .
Déborah Temple, Pol Llonch, Eva Mainau & Xavier Manteca. 2024. Advances in Pig Welfare. Advances in Pig Welfare 383 407 .
Nicola Gladden. (2023) Newborn calf welfare: effects of birth assistance, colostrum feeding and cow–calf separation. Livestock 28:2, pages 58-64.
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Karen Tajonar, Manuel Gonzalez-Ronquillo, Alejandro Relling, Rebecca E. Nordquist, Christian Nawroth & Einar Vargas-Bello-Pérez. (2023) Toward assessing the role of dietary fatty acids in lamb's neurological and cognitive development. Frontiers in Veterinary Science 10.
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Gerry Hish. 2023. Anesthesia and Analgesia in Laboratory Animals. Anesthesia and Analgesia in Laboratory Animals 691 710 .
Wan Tai Seet, Mohd Asyraf Mat Afandi, Sharen Aini Shamsuddin, Yogeswaran Lokanathan, Min Hwei Ng & Manira Maarof. 2022. Stem Cell Production. Stem Cell Production 37 68 .
Angela Baysinger, Sherrie R. Webb, Jennifer Brown, Johann F. Coetzee, Sara Crawford, Ashley DeDecker, Locke A. Karriker, Monique Pairis-Garcia, Mhairi A. Sutherland & Abbie V. Viscardi. (2021) Proposed multidimensional pain outcome methodology to demonstrate analgesic drug efficacy and facilitate future drug approval for piglet castration. Animal Health Research Reviews 22:2, pages 163-176.
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Ignaz Zitterer & Peter Paulsen. (2021) Slaughter of Pregnant Cattle at an Austrian Abattoir: Prevalence and Gestational Age. Animals 11:8, pages 2474.
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Corrina Reithmayer, Michael Danne & Oliver Mußhoff. (2020) Societal attitudes towards in ovo gender determination as an alternative to chick culling. Agribusiness 37:2, pages 306-323.
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João Simões & George StilwellJoão Simões & George Stilwell. 2021. Calving Management and Newborn Calf Care. Calving Management and Newborn Calf Care 51 79 .
Agustín Orihuela & Rodolfo Ungerfeld. (2019) Tail docking in sheep (Ovis aries): A review on the arguments for and against the procedure, advantages/disadvantages, methods, and new evidence to revisit the topic. Livestock Science 230, pages 103837.
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David Mellor. (2019) Preparing for Life After Birth: Introducing the Concepts of Intrauterine and Extrauterine Sensory Entrainment in Mammalian Young. Animals 9:10, pages 826.
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Søren Saxmose Nielsen, Peter Sandøe, Stine Ulrich Kjølsted & Jørgen Steen Agerholm. (2019) Slaughter of Pregnant Cattle in Denmark: Prevalence, Gestational Age, and Reasons. Animals 9:7, pages 392.
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Clare J Phythian, Joseph W Angell, James Patrick Crilly & Adam D Martin. (2019) Ewe Caesarean section: reviewing the evidence base and sharing cross-country experiences part two. Livestock 24:3, pages 149-154.
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David Mellor. (2018) Tail Docking of Canine Puppies: Reassessment of the Tail’s Role in Communication, the Acute Pain Caused by Docking and Interpretation of Behavioural Responses. Animals 8:6, pages 82.
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Déborah Temple, Pol Llonch, Eva Mainau & Xavier Manteca. 2018. Advances in Pig Welfare. Advances in Pig Welfare 357 379 .
Simon More, Dominique Bicout, Anette Botner, Andrew Butterworth, Paolo Calistri, Klaus Depner, Sandra Edwards, Bruno Garin‐Bastuji, Margaret Good, Christian Gortazar Schmidt, Virginie Michel, Miguel Angel Miranda, Søren Saxmose Nielsen, Antonio Velarde, Hans‐Hermann Thulke, Liisa Sihvonen, Hans Spoolder, Jan Arend Stegeman, Mohan Raj, Preben Willeberg, Denise Candiani & Christoph Winckler. (2017) Animal welfare aspects in respect of the slaughter or killing of pregnant livestock animals (cattle, pigs, sheep, goats, horses). EFSA Journal 15:5.
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Nancy De Briyne, Charlotte Berg, Thomas Blaha & Déborah Temple. (2016) Pig castration: will the EU manage to ban pig castration by 2018?. Porcine Health Management 2:1.
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Patric Maurer, Ernst Lücker & Katharina Riehn. (2016) Slaughter of pregnant cattle in German abattoirs – current situation and prevalence: a cross-sectional study. BMC Veterinary Research 12:1.
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Martin G. Thomas, Roxanne M. Marwood, Anna E. Parsons & Richard B. Parsons. (2015) The effect of foetal bovine serum supplementation upon the lactate dehydrogenase cytotoxicity assay: Important considerations for in vitro toxicity analysis. Toxicology in Vitro 30:1, pages 300-308.
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Vivek Phani Varma, Lalitha Devi, Naresh Kumar Venna, Ch Lakshmi N. Murthy, Mohammed M. Idris & Sandeep Goel. (2015) Ocular Fluid As a Replacement for Serum in Cell Cryopreservation Media. PLOS ONE 10:7, pages e0131291.
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Rasmus R. Simonsen. 2015. Biopolitics and Utopia. Biopolitics and Utopia 167 190 .
MLH Campbell, DJ Mellor & P SandØe. (2023) How should the welfare of fetal and neurologically immature postnatal animals be protected?. Animal Welfare 23:4, pages 369-379.
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Hatim Hemeda, Bernd Giebel & Wolfgang Wagner. (2014) Evaluation of human platelet lysate versus fetal bovine serum for culture of mesenchymal stromal cells. Cytotherapy 16:2, pages 170-180.
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T. J. Diesch & D. J. Mellor. (2013) Birth transitions: Pathophysiology, the onset of consciousness and possible implications for neonatal maladjustment syndrome in the foal. Equine Veterinary Journal 45:6, pages 656-660.
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Christine F. Murray & Ken E. Leslie. (2013) Newborn calf vitality: Risk factors, characteristics, assessment, resulting outcomes and strategies for improvement. The Veterinary Journal 198:2, pages 322-328.
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Chan-Ung Wang, Yoshie Arai, Insun Kim, Wonhee Jang, Seonghyun Lee, Jason H. Hafner, Eunhee Jeoung, Deokho Jung & Youngeun Kwon. (2012) Surface-modified gold nanorods for specific cell targeting. Journal of the Korean Physical Society 60:10, pages 1700-1707.
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Chandana Tekkatte, Gency Ponrose Gunasingh, K. M. Cherian & Kavitha Sankaranarayanan. (2011) “Humanized” Stem Cell Culture Techniques: The Animal Serum Controversy. Stem Cells International 2011, pages 1-14.
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David Morton & Jann Hau. 2010. Handbook of Laboratory Animal Science, Volume I, Third Edition. Handbook of Laboratory Animal Science, Volume I, Third Edition 535 572 .
T J Diesch, D J Mellor, C B Johnson & R G Lentle. (2010) Developmental changes in the electroencephalogram and responses to a noxious stimulus in anaesthetized tammar wallaby joeys ( Macropus eugenii eugenii ) . Laboratory Animals 44:2, pages 79-87.
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David J. Mellor. (2010) Galloping Colts, Fetal Feelings, and Reassuring Regulations: Putting Animal-Welfare Science into Practice. Journal of Veterinary Medical Education 37:1, pages 94-100.
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Daniel Boesch, Adrian Steiner, Lorenz Gygax & Markus Stauffacher. (2008) Burdizzo castration of calves less than 1-week old with and without local anaesthesia: Short-term behavioural responses and plasma cortisol levels. Applied Animal Behaviour Science 114:3-4, pages 330-345.
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David J. Mellor & Angus Campbell David Bayvel. (2008) New Zealand's inclusive science-based system for setting animal welfare standards. Applied Animal Behaviour Science 113:4, pages 313-329.
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. (2008) Food Safety, Animal Health and Welfare and Environmental Impact of Animals derived from Cloning by Somatic Cell Nucleus Transfer (SCNT) and their Offspring and Products Obtained from those Animals. EFSA Journal 6:7.
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C.M. Dwyer. (2008) The welfare of the neonatal lamb. Small Ruminant Research 76:1-2, pages 31-41.
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J.C. Murrell, D.J. Mellor & C.B. Johnson. 2008. Anesthesia and Analgesia in Laboratory Animals. Anesthesia and Analgesia in Laboratory Animals 593 608 .
George J. DeMarco & Peter J. Pascoe. 2008. Anesthesia and Analgesia in Laboratory Animals. Anesthesia and Analgesia in Laboratory Animals 3 25 .
D. J. Mellor. 2007. Diseases of Sheep. Diseases of Sheep 22 27 .
Robert Combes & Michael Balls. (2019) Comments on the Sub-group Reports of the EU Technical Expert Working Group on the Revision of Directive 86/609/EEC on the Protection of Animals Used for Experimental and Other Scientific Purposes . Alternatives to Laboratory Animals 35:1, pages 155-175.
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David J. Mellor & Tamara J. Diesch. (2006) Onset of sentience: The potential for suffering in fetal and newborn farm animals. Applied Animal Behaviour Science 100:1-2, pages 48-57.
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. (2005) Opinion of the Scientific Panel on Animal Health and Welfare (AHAW) on a request from the Commission related to the aspects of the biology and welfare of animals used for experimental and other scientific purposes. EFSA Journal 3:12, pages 292.
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David J. Mellor, Tamara J. Diesch, Alistair J. Gunn & Laura Bennet. (2005) The importance of ‘awareness’ for understanding fetal pain. Brain Research Reviews 49:3, pages 455-471.
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N.G. Gregory. (2005) Recent concerns about stunning and slaughter. Meat Science 70:3, pages 481-491.
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. 2004. Physiology and Behaviour of Animal Suffering. Physiology and Behaviour of Animal Suffering 232 257 .
D.J. Mellor & K.J. Stafford. (2004) Animal welfare implications of neonatal mortality and morbidity in farm animals. The Veterinary Journal 168:2, pages 118-133.
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. (2004) Opinion of the Scientific Panel on Animal Health and Welfare (AHAW) on a request from the Commission related to welfare aspects of the main systems of stunning and killing the main commercial species of animals. EFSA Journal 2:7, pages 45.
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DJ Mellor & KE Littin. (2023) Using science to support ethical decisions promoting humane livestock slaughter and vertebrate pest control. Animal Welfare 13:S1, pages S127-S132.
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J. van der Valk, D. Mellor, R. Brands, R. Fischer, F. Gruber, G. Gstraunthaler, L. Hellebrekers, J. Hyllner, F.H. Jonker, P. Prieto, M. Thalen & V. Baumans. (2004) The humane collection of fetal bovine serum and possibilities for serum-free cell and tissue culture. Toxicology in Vitro 18:1, pages 1-12.
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Vera Baumans(Moderator). (2019) Report of the Workshop on Fetal Bovine Serum Replacement in Cell Cultures. Alternatives to Laboratory Animals 32:1_suppl, pages 117-118.
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