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Xenobiotica
the fate of foreign compounds in biological systems
Volume 30, 2000 - Issue 11
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Research Article

Effects of clofibrate and indocyanine green on the hepatobiliary disposition of acetaminophen and its metabolites in male CD-1 mice

Chuan Chen Pharmaceutical Sciences
,
Gayle E. Hennig Pathobiology, University of Connecticut, Storrs, CT 06269, USA
,
Denis J. McCann Drug Disposition and Metabolism Department, AstraZeneca Pharmaceuticals, Wilmington, DE 19850, USA
&
José E. Manautou Toxicology Program, Departments of Pharmaceutical Sciences and Pathobiology, University of Connecticut, Storrs, CT 06269, USA
Pages 1019-1032 | Published online: 22 Sep 2008

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Sudeepa Bhattacharyya, Ke Yan, Lisa Pence, Pippa M Simpson, Pritmohinder Gill, Lynda G Letzig, Richard D Beger, Janice E Sullivan, Gregory L Kearns, Michael D Reed, James D Marshall, John N Van Den Anker & Laura P James. (2014) Targeted Liquid Chromatography–Mass Spectrometry Analysis of Serum Acylcarnitines in Acetaminophen Toxicity in Children. Biomarkers in Medicine 8:2, pages 147-159.
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Articles from other publishers (13)

Gary H. Perdew, Iain A. Murray, Andrew D. Patterson & Jeffrey M. Peters. 2024. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
G.H. Perdew, I.A. Murray, A.D. Patterson & J.M. Peters. 2018. Comprehensive Toxicology. Comprehensive Toxicology 202 228 .
J.E. Moscovitz, L. Gorczyca & L.M. Aleksunes. 2017. Drug Metabolism in Diseases. Drug Metabolism in Diseases 207 240 .
Daniel W. Ferreira, Michael J. Goedken, Samuel Rommelaere, Lionel Chasson, Franck Galland, Philippe Naquet & José E. Manautou. (2016) Enhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1862:4, pages 662-669.
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Alessandra Milesi-Hallé, Susan M. Abdel-Rahman, Aliza Brown, Sandra S. McCullough, Lynda Letzig, Jack A. Hinson & Laura P. James. (2011) Indocyanine green clearance varies as a function of N-acetylcysteine treatment in a murine model of acetaminophen toxicity. Chemico-Biological Interactions 189:3, pages 222-229.
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G.H. Perdew, I.A. Murray & J.M. Peters. 2010. Comprehensive Toxicology. Comprehensive Toxicology 361 388 .
Guoli Dai, Lin He, Nathan Chou & Yu-Jui Yvonne Wan. (2006) Acetaminophen Metabolism Does Not Contribute to Gender Difference in Its Hepatotoxicity in Mouse. Toxicological Sciences 92:1, pages 33-41.
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Jeffrey S. Moffit, Lauren M. Aleksunes, Jonathan M. Maher, George L. Scheffer, Curtis D. Klaassen & José E. Manautou. (2006) Induction of Hepatic Transporters Multidrug Resistance-Associated Proteins (Mrp) 3 and 4 by Clofibrate Is Regulated by Peroxisome Proliferator-Activated Receptor α. Journal of Pharmacology and Experimental Therapeutics 317:2, pages 537-545.
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Guoli Dai, Nathan Chou, Lin He, Maxwell A. Gyamfi, Alphonse J. Mendy, Angela L. Slitt, Curtis D. Klaassen & Yu-Jui Y. Wan. (2005) Retinoid X Receptor α Regulates the Expression of Glutathione S -transferase Genes and Modulates Acetaminophen-Glutathione Conjugation in Mouse Liver . Molecular Pharmacology 68:6, pages 1590-1596.
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Vanessa M. Silva, Michael S. Thibodeau, Chuan Chen & José E. Manautou. (2005) Transport deficient (TR−) hyperbilirubinemic rats are resistant to acetaminophen hepatotoxicity. Biochemical Pharmacology 70:12, pages 1832-1839.
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A. L. Slitt, N. J. Cherrington, J. M. Maher & C. D. Klaassen. (2003) INDUCTION OF MULTIDRUG RESISTANCE PROTEIN 3 IN RAT LIVER IS ASSOCIATED WITH ALTERED VECTORIAL EXCRETION OF ACETAMINOPHEN METABOLITES. Drug Metabolism and Disposition 31:9, pages 1176-1186.
Crossref
Chuan Chen, Gayle E. Hennig, Herbert E. Whiteley & José E. Manautou. (2002) Protection against acetaminophen hepatotoxicity by clofibrate pretreatment: Role of catalase induction. Journal of Biochemical and Molecular Toxicology 16:5, pages 227-234.
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V.M Silva, C Chen, G.E Hennig, H.E Whiteley & J.E Manautou. (2001) Changes in susceptibility to acetaminophen-induced liver injury by the organic anion indocyanine green. Food and Chemical Toxicology 39:3, pages 271-278.
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