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Xenobiotica
the fate of foreign compounds in biological systems
Volume 30, 2000 - Issue 11
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Research Article

In vitro identification of the cytochrome P450 isoform responsible for the metabolism of a-dihydroergocryptine

M. Althaus Desitin Arzneimittel GmbH, Weg beim Jager 214, D-22335 Hamburg, Germany
,
A. Retzow Unidad de Hepatologia Experimental, Centro de Investigacion, Hospital Universitario La Fe, E-46009 Valencia, Spain
,
J. V. Castell Pharmbiodyn GmbH, Ferdinand-Porsche-Strasse 5, D-79211 Denzlingen, Germany
,
M.-J. Gómez-Lechón Desitin Arzneimittel GmbH, Weg beim Jager 214, D-22335 Hamburg, Germany
,
Z. Amalou Unidad de Hepatologia Experimental, Centro de Investigacion, Hospital Universitario La Fe, E-46009 Valencia, Spain
,
T. Rose Pharmbiodyn GmbH, Ferdinand-Porsche-Strasse 5, D-79211 Denzlingen, Germany
&
K. Appel Desitin Arzneimittel GmbH, Weg beim Jager 214, D-22335 Hamburg, Germany
 show all
Pages 1033-1045 | Published online: 22 Sep 2008

Citations (9)

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Read on this site (2)

J. M. Duringer, R. Lewis, L. Kuehn, T. Fleischmann & A. M. Craig. (2005) Growth and hepatic in vitro metabolism of ergotamine in mice divergently selected for response to endophyte toxicity. Xenobiotica 35:6, pages 531-548.
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Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
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Articles from other publishers (7)

Lia D. Murty, Jennifer M. Duringer & A. Morrie Craig. (2018) Co-exposure of the Mycotoxins Lolitrem B and Ergovaline in Steers Fed Perennial Ryegrass ( Lolium perenne ) Straw: Metabolic Characterization of Excreta . Journal of Agricultural and Food Chemistry 66:25, pages 6394-6401.
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Charles F. Rosenkrans & Nicholas S. Ezell. (2015) Relationships among ergot alkaloids, cytochrome P450 activity, and beef steer growth. Frontiers in Chemistry 3.
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Jennifer M. Duringer, Lia Murty & A. Morrie Craig. 2013. Phytochemicals, Plant Growth, and the Environment. Phytochemicals, Plant Growth, and the Environment 37 58 .
Ali S. Moubarak, Hehai Wang, Zelpha B. Johnson & Charles F. Rosenkrans. (2012) Interaction of ergotamine with liver Cytochrome P450 3A in rats. Agricultural Sciences 03:06, pages 795-798.
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Raja S. Settivari, Tim J. Evans, Ed Rucker, George E. Rottinghaus & Donald E. Spiers. (2008) Effect of ergot alkaloids associated with fescue toxicosis on hepatic cytochrome P450 and antioxidant proteins. Toxicology and Applied Pharmacology 227:3, pages 347-356.
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Beatriz Bicalho, Juliana Marconi Giolo, Sergio Lilla & Gilberto De Nucci. (2007) Identification and human pharmacokinetics of dihydroergotoxine metabolites in man: preliminary results. Biopharmaceutics & Drug Disposition 29:1, pages 17-28.
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Michael Wink. 2007. 1 47 .

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