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Xenobiotica
the fate of foreign compounds in biological systems
Volume 31, 2001 - Issue 1
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Research Article

Metabolism of 2-nitrofluorene, 2-aminofluorene and 2-acylaminofluorenes in rat and dog and the role of intestinal bacteria

O. Ueda Institute of Pharmaceutical Science, Hiroshima University School of Medicine, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan
,
S. Kitamura Institute of Pharmaceutical Science, Hiroshima University School of Medicine, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan
,
R. Kubo Institute of Pharmaceutical Science, Hiroshima University School of Medicine, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan
,
Y. Yano Institute of Pharmaceutical Science, Hiroshima University School of Medicine, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan
,
Y. Kanzaki Institute of Pharmaceutical Science, Hiroshima University School of Medicine, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan
,
T. Fujimoto Institute of Pharmaceutical Science, Hiroshima University School of Medicine, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan
,
K. Tatsumi Institute of Pharmaceutical Science, Hiroshima University School of Medicine, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan
&
S. Ohta Institute of Pharmaceutical Science, Hiroshima University School of Medicine, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8551, Japan
 show all
Pages 33-49 | Published online: 22 Sep 2008

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Saulius Armalis, Natalija Novikova, Erika Kubiliene, Jiri Zima & Jiri Barek. (2002) VOLTAMMETRIC DETERMINATION OF 2-AMINOFLUORENE AND 2,7-DIAMINOFLUORENE USING CARBON PASTE ELECTRODE. Analytical Letters 35:9, pages 1551-1559.
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Articles from other publishers (15)

Junhua Zhou, Xin Zhang, Yanwei Li, Shanshan Feng, Qingzhu Zhang & Wenxing Wang. (2022) Endocrine-disrupting metabolic activation of 2-nitrofluorene catalyzed by human cytochrome P450 1A1: A QM/MM approach. Environment International 166, pages 107355.
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L. Chi & K. Lu. 2018. Comprehensive Toxicology. Comprehensive Toxicology 59 73 .
Tatyana Y. Doktorova, Gamze Ates, Mathieu Vinken, Tamara Vanhaecke & Vera Rogiers. (2014) Way forward in case of a false positive in vitro genotoxicity result for a cosmetic substance?. Toxicology in Vitro 28:1, pages 54-59.
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Tatyana Y. Doktorova, Reha Yildirimman, Mathieu Vinken, Mireia Vilardell, Tamara Vanhaecke, Hans Gmuender, Roque Bort, Gabriella Brolen, Gustav Holmgren, Ruoya Li, Christophe Chesne, Joost van Delft, Jos Kleinjans, Jose Castell, Petter Bjorquist, Ralf Herwig & Vera Rogiers. (2013) Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models. Carcinogenesis 34:6, pages 1393-1402.
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Tatyana Y. Doktorova, Heidrun Ellinger-Ziegelbauer, Mathieu Vinken, Tamara Vanhaecke, Joost van Delft, Jos Kleinjans, Hans-Juergen Ahr & Vera Rogiers. (2012) Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data. Archives of Toxicology 86:11, pages 1703-1715.
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Vlastimil Vyskočil, Ján Labuda & Jiří Barek. (2010) Voltammetric detection of damage to DNA caused by nitro derivatives of fluorene using an electrochemical DNA biosensor. Analytical and Bioanalytical Chemistry 397:1, pages 233-241.
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Shigeyuki Kitamura, Kazumi Sugihara, Seigo Sanoh, Nariaki Fujimoto & Shigeru Ohta. (2008) Metabolic Activation of Proestrogens in the Environment by Cytochrome P450 System. Journal of Health Science 54:4, pages 343-355.
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Di Wu, Zengru Wu, Jun Yang, Vipin A. Nair, Duane D. Miller & James T. Dalton. (2006) PHARMACOKINETICS AND METABOLISM OF A SELECTIVE ANDROGEN RECEPTOR MODULATOR IN RATS: IMPLICATION OF MOLECULAR PROPERTIES AND INTENSIVE METABOLIC PROFILE TO INVESTIGATE IDEAL PHARMACOKINETIC CHARACTERISTICS OF A PROPANAMIDE IN PRECLINICAL STUDY. Drug Metabolism and Disposition 34:3, pages 483-494.
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Osamu Ueda, Kazumi Sugihara, Shigeru Ohta & Shigeyuki Kitamura. (2005) INVOLVEMENT OF MOLYBDENUM HYDROXYLASES IN REDUCTIVE METABOLISM OF NITRO POLYCYCLIC AROMATIC HYDROCARBONS IN MAMMALIAN SKIN. Drug Metabolism and Disposition 33:9, pages 1312-1318.
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Natalija German, Saulius Armalis, Jiří Zima & Jiří Barek. (2005) Voltammetric Determination of Fluoren-9-ol and 2-Acetamidofluorene Using Carbon Paste Electrodes. Collection of Czechoslovak Chemical Communications 70:3, pages 292-304.
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Jack Uetrecht. 2003. Drug Metabolizing Enzymes. Drug Metabolizing Enzymes 87 145 .
Osamu Ueda, Shigeyuki Kitamura, Koji Ohashi, Kazumi Sugihara & Shigeru Ohta. (2003) Xanthine Oxidase-Catalyzed Metabolism of 2-Nitrofluorene, a Carcinogenic Air Pollutant, in Rat Skin. Drug Metabolism and Disposition 31:4, pages 367-372.
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Takashi Fujimoto, Shigeyuki Kitamura, Seigo Sanoh, Kazumi Sugihara, Shin’ichi Yoshihara, Nariaki Fujimoto & Shigeru Ohta. (2003) Estrogenic activity of an environmental pollutant, 2-nitrofluorene, after metabolic activation by rat liver microsomes. Biochemical and Biophysical Research Communications 303:2, pages 419-426.
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Shigeyuki Kitamura, Osamu Ueda, Kazumi Sugihara & Shigeru Ohta. (2003) Deacylation of N-Formylanilines and N-Acetylanilines by Rat Liver Formamidase. Journal of Health Science 49:6, pages 501-508.
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Osamu Ueda, Shigeyuki Kitamura & Shigeru Ohta. (2002) Deacylation of N -Arylformamides and N -Arylacetamides by Formamidase in Rat Liver . Drug Metabolism and Disposition 30:12, pages 1297-1299.
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