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Xenobiotica
the fate of foreign compounds in biological systems
Volume 30, 2000 - Issue 5
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Research Article

Identification of cytochrome P450 isoform involved in the metabolism of YM992, a novel selective serotonin re-uptake inhibitor, in human liver microsomes

K. Noguchi Drug Metabolism Laboratories, Yamanouchi Pharmaceutical Co., Ltd, 1- 8, Azusawa 1-chome, Itabashi-ku, Tokyo 174- 8511, Japan
,
A. Mera Drug Metabolism Laboratories, Yamanouchi Pharmaceutical Co., Ltd, 1- 8, Azusawa 1-chome, Itabashi-ku, Tokyo 174- 8511, Japan
,
T. Watanabe Drug Metabolism Laboratories, Yamanouchi Pharmaceutical Co., Ltd, 1- 8, Azusawa 1-chome, Itabashi-ku, Tokyo 174- 8511, Japan
,
S. Higuchi Drug Metabolism Laboratories, Yamanouchi Pharmaceutical Co., Ltd, 1- 8, Azusawa 1-chome, Itabashi-ku, Tokyo 174- 8511, Japan
&
K. Chiba Drug Metabolism Laboratories, Yamanouchi Pharmaceutical Co., Ltd, 1- 8, Azusawa 1-chome, Itabashi-ku, Tokyo 174- 8511, Japan
Pages 503-513 | Published online: 22 Sep 2008

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Read on this site (2)

Shu-Feng Zhou, Bo Wang, Li-Ping Yang & Jun-Ping Liu. (2010) Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2. Drug Metabolism Reviews 42:2, pages 268-354.
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Slobodan Rendic. (2002) Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metabolism Reviews 34:1-2, pages 83-448.
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Articles from other publishers (2)

Yasushi Yamazoe, Yoshiya Yamamura & Kouichi Yoshinari. (2022) Construction of a fused grid-based template system of CYP2C9 and its application. Drug Metabolism and Pharmacokinetics 45, pages 100451.
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Yuji Mano, Saburo Higuchi & Hidetaka Kamimura. (2002) Investigation of the high partition of YM992, a novel antidepressant, in rat brain ‐ in vitro and in vivo evidence for the high binding in brain and the high permeability at the BBB . Biopharmaceutics & Drug Disposition 23:9, pages 351-360.
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