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Xenobiotica
the fate of foreign compounds in biological systems
Volume 30, 2000 - Issue 10
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Research Article

Characterization of cytochrome P450 enzymes involved in drug oxidations in mouse intestinal microsomes

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Pages 943-953 | Published online: 22 Sep 2008

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Shotaro Uehara, Norie Murayama, Yuichiro Higuchi, Nao Yoneda, Hiroshi Yamazaki & Hiroshi Suemizu. (2022) Comparison of mouse and human cytochrome P450 mediated-drug metabolising activities in hepatic and extrahepatic microsomes. Xenobiotica 52:3, pages 229-239.
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Kornphimol Kulthong, Rawiwan Maniratanachote, Yuki Kobayashi, Tatsuki Fukami & Tsuyoshi Yokoi. (2012) Effects of silver nanoparticles on rat hepatic cytochrome P450 enzyme activity. Xenobiotica 42:9, pages 854-862.
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Noriaki Yoda, Chie Emoto, Shoichi Date, Satoshi Kondo, Masateru Miyake, Satoru Nakazato, Ken Umehara & Eiji Kashiyama. (2012) Characterization of intestinal and hepatic P450 enzymes in cynomolgus monkeys with typical substrates and inhibitors for human P450 enzymes. Xenobiotica 42:8, pages 719-730.
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T. Toda, N. Saito, N. Ikarashi, K. Ito, M. Yamamoto, A. Ishige, K. Watanabe & K. Sugiyama. (2009) Intestinal flora induces the expression of Cyp3a in the mouse liver. Xenobiotica 39:4, pages 323-334.
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S. Kurosawa, S. Uchida, Y. Ito,S. Yamada. (2009) Effect of ursodeoxycholic acid on the pharmacokinetics of midazolam and CYP3A in the liver and intestine of rats. Xenobiotica 39:2, pages 162-170.
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Nicola J. Hewitt, María José Gómez Lechón, J. Brian Houston, David Hallifax, Hayley S. Brown, Patrick Maurel, J. Gerald Kenna, Lena Gustavsson, Christina Lohmann, Christian Skonberg, Andre Guillouzo, Gregor Tuschl, Albert P. Li, Edward LeCluyse, Geny M. M. Groothuis & Jan G. Hengstler. (2007) Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies. Drug Metabolism Reviews 39:1, pages 159-234.
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C. Emoto, H. Yamazaki, H. Iketaki, S. Yamasaki, T. Satoh, R. Shimizu, S. Suzuki, N. Shimada, M. Nakajima & T. Yokoi. (2001) Cooperativity of α-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human. Xenobiotica 31:5, pages 265-275.
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