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Xenobiotica
the fate of foreign compounds in biological systems
Volume 33, 2003 - Issue 3
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Research Article

mRNA and protein expression of dog liver cytochromes P450 in relation to the metabolism of human CYP2C substrates

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Pages 225-237 | Published online: 22 Sep 2008

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Marilyn N. Martinez, Leposava Antonovic, Michael Court, Mauro Dacasto, Johanna Fink-Gremmels, Butch Kukanich, Chuck Locuson, Katrina Mealey, Michael J. Myers & Lauren Trepanier. (2013) Challenges in exploring the cytochrome P450 system as a source of variation in canine drug pharmacokinetics. Drug Metabolism Reviews 45:2, pages 218-230.
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Gerhard Gross & Ian Wilson. (2009) Issues in the Safety Testing of Metabolites. Future Medicinal Chemistry 1:8, pages 1381-1390.
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M. Turpeinen, C. Ghiciuc, M. Opritoui, L. Tursas, O. Pelkonen & M. Pasanen. (2007) Predictive value of animal models for human cytochrome P450 (CYP)-mediated metabolism: A comparative study . Xenobiotica 37:12, pages 1367-1377.
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M. Ishizuka, S. Nagai, K. Q. Sakamoto & S. Fujita. (2007) Plasma pharmacokinetics and CYP3A12-dependent metabolism of c-kit inhibitor imatinib in dogs. Xenobiotica 37:5, pages 503-513.
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Marcella Martignoni, Geny M M Groothuis & Ruben de Kanter. (2006) Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opinion on Drug Metabolism & Toxicology 2:6, pages 875-894.
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Carrie M. Mosher & Michael H. Court. 2010. Comparative and Veterinary Pharmacology. Comparative and Veterinary Pharmacology 49 77 .
Frederique Bravin, Radu Duca, Patrick Balaguer & Marcel Delaforge. (2009) In Vitro Cytochrome P450 Formation of a Mono-Hydroxylated Metabolite of Zearalenone Exhibiting Estrogenic Activities: Possible Occurrence of This Metabolite in Vivo. International Journal of Molecular Sciences 10:4, pages 1824-1837.
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Robert P. Hunter & Ramiro Isaza. (2008) Concepts and Issues with Interspecies Scaling in Zoological Pharmacology. Journal of Zoo and Wildlife Medicine 39:4, pages 517-526.
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Stefanie D. Krämer & Bernard Testa. (2008) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 5:12, pages 2465-2578.
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H. Kamimura. (2006) Genetic polymorphism of cytochrome P450s in beagles: possible influence of CYP1A2 deficiency on toxicological evaluations. Archives of Toxicology 80:11, pages 732-738.
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Lauren A. Trepanier. (2006) Cytochrome P450 and Its Role in Veterinary Drug Interactions. Veterinary Clinics of North America: Small Animal Practice 36:5, pages 975-985.
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