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Xenobiotica
the fate of foreign compounds in biological systems
Volume 33, 2003 - Issue 3
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Research Article

Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of ethosuximide by human hepatic microsomal enzymes

K. Bachmann Department of Pharmacology, University of Toledo College of Pharmacy, 2801 W. Bancroft Street, Toledo, OH 43606, USA
,
Y. He Department of Pharmacology, University of Toledo College of Pharmacy, 2801 W. Bancroft Street, Toledo, OH 43606, USA
,
J. G. Sarver Department of Pharmacology, University of Toledo College of Pharmacy, 2801 W. Bancroft Street, Toledo, OH 43606, USA
&
Ning Peng Department of Pharmacology, University of Toledo College of Pharmacy, 2801 W. Bancroft Street, Toledo, OH 43606, USA
Pages 265-276 | Published online: 22 Sep 2008

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Yasushi Yamazoe, Kazumi Ito & Kouichi Yoshinari. (2011) Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order. Drug Metabolism Reviews 43:4, pages 409-439.
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M. D. Lee, E. Ayanoglu & L. Gong. (2006) Drug-induced changes in P450 enzyme expression at the gene expression level: A new dimension to the analysis of drug–drug interactions. Xenobiotica 36:10-11, pages 1013-1080.
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Articles from other publishers (14)

Kana Mizuno, Edmund V. Capparelli, Tsuyoshi Fukuda, Min Dong, Peter C. Adamson, Jeffery L. Blumer, Avital Cnaan, Peggy O. Clark, Michael D. Reed, Shlomo Shinnar, Alexander A. Vinks & Tracy A. Glauser. (2023) Model‐Informed Precision Dosing Guidance of Ethosuximide Developed from a Randomized Controlled Clinical Trial of Childhood Absence Epilepsy. Clinical Pharmacology & Therapeutics 114:2, pages 459-469.
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Risa Sato, Kotaro Ohmori, Mina Umetsu, Masaki Takao, Mitsutoshi Tano, Gerald Grant, Brenda Porter, Anthony Bet, Tetsuya Terasaki & Yasuo Uchida. (2021) An Atlas of the Quantitative Protein Expression of Anti-Epileptic-Drug Transporters, Metabolizing Enzymes and Tight Junctions at the Blood–Brain Barrier in Epileptic Patients. Pharmaceutics 13:12, pages 2122.
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Hanqing Shang, Mica Glaun & Julina Ongkasuwan. (2021) Ethosuximide induced macroglossia and oropharyngeal edema. International Journal of Pediatric Otorhinolaryngology 140, pages 110498.
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Tracy A. Glauser & Emilio Perucca. 2015. The Treatment of Epilepsy. The Treatment of Epilepsy 460 471 .
Gail D. Anderson & Shahin Hakimian. (2013) Pharmacokinetic of Antiepileptic Drugs in Patients with Hepatic or Renal Impairment. Clinical Pharmacokinetics 53:1, pages 29-49.
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Danièle Bentué-Ferrer, Olivier Tribut & Marie-Clémence Verdier. (2012) Suivi thérapeutique pharmacologique de l’éthosuximide. Therapies 67:4, pages 391-396.
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Jose de Leon. 2012. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities. A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities 95 106 .
Ling Zhi Yu & Xian Le Yang. (2010) Effects of fish cytochromes P450 inducers and inhibitors on difloxacin N-demethylation in kidney of Chinese idle (Ctenopharyngodon idellus). Environmental Toxicology and Pharmacology 29:3, pages 202-208.
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Chakorn Chansakul & Steve S. Chung. 2010. Atlas of Epilepsies. Atlas of Epilepsies 1741 1748 .
Chantal Schlatter, Sabin S. Egger, Lydia Tchambaz & Stephan Krähenbühl. (2009) Pharmacokinetic Changes of Psychotropic Drugs in Patients with Liver Disease. Drug Safety 32:7, pages 561-578.
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Scott Mintzer. 2009. Pharmacology and Therapeutics. Pharmacology and Therapeutics 663 683 .
Akash Khandelwal, Praveen M. Bahadduri, Cheng Chang, James E. Polli, Peter W. Swaan & Sean Ekins. (2007) Computational Models to Assign Biopharmaceutics Drug Disposition Classification from Molecular Structure. Pharmaceutical Research 24:12, pages 2249-2262.
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Rubeen K. Israni, Nishaminy Kasbekar, Kevin Haynes & Jeffrey S. Berns. (2006) Use of Antiepileptic Drugs in Patients with Kidney Disease. Seminars in Dialysis 19:5, pages 408-416.
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J. S. Millership, J. Mifsud, D. Galea, W. C. McRoberts & J. T. G. Hamilton. (2005) Chiral aspects of the human metabolism of ethosuximide. Biopharmaceutics & Drug Disposition 26:6, pages 225-232.
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