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Xenobiotica
the fate of foreign compounds in biological systems
Volume 32, 2002 - Issue 6
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Research Article

Metabolism of 4-fluoroaniline and 4-fluorobiphenyl in the earthworm Eisenia veneta characterized by high-resolution NMR spectroscopy with directly coupled HPLC-NMR and HPLC-MS

J. G. Bundy Biological Chemistry, Biomedical Sciences Division, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, UK
,
E. M. Lenz Centre for Ecology and Hydrology, Monks Wood, Abbots Ripton, Huntingdon PE28 2LS, UK
,
D. Osborn Biological Chemistry, Biomedical Sciences Division, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, UK
,
J. M. Weeks Centre for Ecology and Hydrology, Monks Wood, Abbots Ripton, Huntingdon PE28 2LS, UK
,
J. C. Lindon Biological Chemistry, Biomedical Sciences Division, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, UK
&
J. K. Nicholson Centre for Ecology and Hydrology, Monks Wood, Abbots Ripton, Huntingdon PE28 2LS, UK
Pages 479-490 | Published online: 22 Sep 2008

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Sunil Sarda, Chris Page, Kathryn Pickup, Timothy Schulz-Utermoehl & Ian Wilson. (2012) Diclofenac metabolism in the mouse: Novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry. Xenobiotica 42:2, pages 179-194.
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C. J. Duckett, I. D. Wilson, D. S. Douce, H. J. Walker, F. R. Abou-Shakra, J. C. Lindon & J. K. Nicholson. (2007) Metabolism of 2-fluoro-4-iodoaniline in earthworm using 19F-NMR spectroscopy, HPLC-MS, and HPLC-ICPMS (127I). Xenobiotica 37:12, pages 1378-1393.
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E. M. Lenz, J. C. Lindon, J. K. Nicholson, J. M. Weeks & D. Osborn. (2002) 19 F-NMR and directly coupled 19 F/ 1 H-HPLC-NMR spectroscopic investigations of the metabolism of the model ecotoxin 3-trifluoromethylaniline in the earthworm species Eisenia veneta. Xenobiotica 32:6, pages 535-546.
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Lei Wang, Xulei Huang, Anna Karen Carrasco Laserna & Sam Fong Yau Li. (2018) Untargeted metabolomics reveals transformation pathways and metabolic response of the earthworm Perionyx excavatus after exposure to triphenyl phosphate. Scientific Reports 8:1.
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Shubo Dong, Hanyue Yang & Deju Ye. (2018) Development of an LC–MS Method for 4-Fluoroaniline Determination in Ezetimibe. Journal of Chromatographic Science 56:8, pages 724-730.
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Lei Wang, Xulei Huang, Anna Karen Carrasco Laserna & Sam Fong Yau Li. (2018) Metabolism of tri-n-butyl phosphate in earthworm Perionyx excavatus. Environmental Pollution 234, pages 389-395.
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Angelica Ramirez Tabche Martha, Jose Pena Cabriales Juan, Maldonado Vega Maria & Antonio Vera-Nunez Jose. (2017) The influence of potassium dichromate on growth and survival of the vermicomposting earthworm Eisenia foetida. African Journal of Biotechnology 16:20, pages 1182-1185.
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Toshiyuki KatagiKeiko Ose. (2015) Toxicity, bioaccumulation and metabolism of pesticides in the earthworm. Journal of Pesticide Science 40:3, pages 69-81.
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James Kinross, Jia V. Li, Laura J. Muirhead & Jeremy Nicholson. (2014) Nutritional modulation of the metabonome. Current Opinion in Gastroenterology 30:2, pages 196-207.
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Brian P. LankaduraiEdward G. NagatoMyrna J. Simpson. (2013) Environmental metabolomics: an emerging approach to study organism responses to environmental stressors. Environmental Reviews 21:3, pages 180-205.
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Yasuhiro Date, Tomohiro Iikura, Akira Yamazawa, Shigeharu Moriya & Jun Kikuchi. (2012) Metabolic Sequences of Anaerobic Fermentation on Glucose-Based Feeding Substrates Based on Correlation Analyses of Microbial and Metabolite Profiling. Journal of Proteome Research 11:12, pages 5602-5610.
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Byeoung-Soo Park, Jae-Hong Yoo, Jeong-Han Kim, Jang-Eok Kim & Sung-Eun Lee. (2012) Biotransformation of endosulfan by the tiger worm, <i>Eisenia fetida</i>. Journal of Agricultural Chemistry and Environment 01:01, pages 20-27.
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Young Soo Keum, Jeong-Han Kim & Qing X. Li. 2012. Encyclopedia of Sustainability Science and Technology. Encyclopedia of Sustainability Science and Technology 1184 1198 .
André J. Simpson, David J. McNally & Myrna J. Simpson. (2011) NMR spectroscopy in environmental research: From molecular interactions to global processes. Progress in Nuclear Magnetic Resonance Spectroscopy 58:3-4, pages 97-175.
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Jimmy Yuk, Myrna J. Simpson & André J. Simpson. (2011) 1-D and 2-D NMR metabolomics of earthworm responses to sub-lethal trifluralin and endosulfan exposure. Environmental Chemistry 8:3, pages 281.
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P.B. Tchounwou & K. Ndebele. 2011. Encyclopedia of Environmental Health. Encyclopedia of Environmental Health 405 414 .
P.B. Tchounwou & K. Ndebele. 2011. Encyclopedia of Environmental Health. Encyclopedia of Environmental Health 403 413 .
David J. Spurgeon, Oliver A.H. Jones, Jean-Lou C.M. Dorne, Claus Svendsen, Suresh Swain & Stephen R. Stürzenbaum. (2010) Systems toxicology approaches for understanding the joint effects of environmental chemical mixtures. Science of The Total Environment 408:18, pages 3725-3734.
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Jimmy Yuk, Jennifer R. McKelvie, Myrna J. Simpson, Manfred Spraul & André J. Simpson. (2010) Comparison of 1-D and 2-D NMR techniques for screening earthworm responses to sub-lethal endosulfan exposure. Environmental Chemistry 7:6, pages 524.
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Young Soo Keum, Jeong-Han Kim & Qing X. Li. 2010. Hayes' Handbook of Pesticide Toxicology. Hayes' Handbook of Pesticide Toxicology 627 643 .
Myrna J. Simpson & Jennifer R. McKelvie. (2009) Environmental metabolomics: new insights into earthworm ecotoxicity and contaminant bioavailability in soil. Analytical and Bioanalytical Chemistry 394:1, pages 137-149.
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Steven L. Cobb & Cormac D. Murphy. (2009) 19F NMR applications in chemical biology. Journal of Fluorine Chemistry 130:2, pages 132-143.
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Zachary A. Hickman & Brian J. Reid. (2008) Earthworm assisted bioremediation of organic contaminants. Environment International 34:7, pages 1072-1081.
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Sarah A. E. Brown, André J. Simpson & Myrna J. Simpson. (2009) Evaluation of sample preparation methods for nuclear magnetic resonance metabolic profiling studies with Eisenia fetida . Environmental Toxicology and Chemistry 27:4, pages 828-836.
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Helen C. Poynton, Henri Wintz & Chris D. Vulpe. 2008. Comparative Toxicogenomics. Comparative Toxicogenomics 21 323 .
Donald G. Robertson. (2005) Metabonomics in Toxicology: A Review. Toxicological Sciences 85:2, pages 809-822.
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E. M. Lenz, J. M. Weeks, J. C. Lindon, D. Osborn & J. K. Nicholson. (2005) Qualitative high field 1H-NMR spectroscopy for the characterization of endogenous metabolites in earthworms with biochemical biomarker potential. Metabolomics 1:2, pages 123-136.
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Jeroen J. Jansen, Huub C.J. Hoefsloot, Jan van der Greef, Marieke E. Timmerman & Age K. Smilde. (2005) Multilevel component analysis of time-resolved metabolic fingerprinting data. Analytica Chimica Acta 530:2, pages 173-183.
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Catherine J. Duckett, Ian D. Wilson, Heather Walker, Fadi Abou‐Shakra, John C. Lindon & Jeremy K. Nicholson. (2003) High‐performance liquid chromatography/inductively coupled plasma mass spectrometry with iodine‐specific detection for profiling the metabolites produced in the earthworm Eisenia veneta by exposure to 2‐fluoro‐4‐iodoaniline . Rapid Communications in Mass Spectrometry 17:16, pages 1855-1858.
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. (2002) Current literature in Journal of Mass Spectrometry. Journal of Mass Spectrometry 37:11, pages 1176-1184.
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Oliver A.H. Jones & Daniel A. Dias. 2007. eMagRes. eMagRes 1 12 .

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