Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 32, 2002 - Issue 7
127
Views
24
CrossRef citations to date
0
Altmetric
Research Article

Species differences in coumarin metabolism: a molecular modelling evaluation of CYP2A interactions

&
Pages 547-561 | Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Kristi L Helke & Marvin Michael Swindle. (2013) Animal models of toxicology testing: the role of pigs. Expert Opinion on Drug Metabolism & Toxicology 9:2, pages 127-139.
Read now
K.H. Tiong, B.C. Yiap, E.L. Tan, R. Ismail & C.E. Ong. (2010) In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity. Xenobiotica 40:7, pages 458-466.
Read now
M. Turpeinen, C. Ghiciuc, M. Opritoui, L. Tursas, O. Pelkonen & M. Pasanen. (2007) Predictive value of animal models for human cytochrome P450 (CYP)-mediated metabolism: A comparative study . Xenobiotica 37:12, pages 1367-1377.
Read now
Marcella Martignoni, Geny M M Groothuis & Ruben de Kanter. (2006) Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction. Expert Opinion on Drug Metabolism & Toxicology 2:6, pages 875-894.
Read now

Articles from other publishers (19)

Sarmistha Mitra, Linh Nhat Nguyen, Mahmuda Akter, Gyungsoon Park, Eun Ha Choi & Nagendra Kumar Kaushik. (2019) Impact of ROS Generated by Chemical, Physical, and Plasma Techniques on Cancer Attenuation. Cancers 11:7, pages 1030.
Crossref
Shuping Li, Liang Teng, Wei Liu, Xuemei Cheng, Bo Jiang, Zhengtao Wang & Changhong Wang. (2016) Interspecies metabolic diversity of harmaline and harmine in in vitro 11 mammalian liver microsomes . Drug Testing and Analysis 9:5, pages 754-768.
Crossref
A. N. Mal’tsev & E. V. Kotenkova. (2014) Divergence of the olfactory signals in subspecies of the house mouse Mus musculus. Biology Bulletin Reviews 4:2, pages 112-121.
Crossref
Ellen M. McDonagh, Catherine Wassenaar, Sean P. David, Rachel F. Tyndale, Russ B. Altman, Michelle Whirl-Carrillo & Teri E. Klein. (2012) PharmGKB summary. Pharmacogenetics and Genomics 22:9, pages 695-708.
Crossref
Stefan Weigt, Nicole Huebler, Ruben Strecker, Thomas Braunbeck & Thomas H. Broschard. (2012) Developmental effects of coumarin and the anticoagulant coumarin derivative warfarin on zebrafish (Danio rerio) embryos. Reproductive Toxicology 33:2, pages 133-141.
Crossref
Alexander V. LyubimovJoshua G. DeKeyser & Magang Shou. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 38 .
Manoja Pretheeban, Geoff Hammond, Stelvio Bandiera, Wayne Riggs & Dan Rurak. (2012) Ontogenesis of phase I hepatic drug metabolic enzymes in sheep. Reproduction, Fertility and Development 24:3, pages 425.
Crossref
Anne S. Kienhuis, Marcel C.G. van de Poll, Cornelis H.C. Dejong, Ralph Gottschalk, Marcel van Herwijnen, André Boorsma, Jos C.S. Kleinjans, Rob H. Stierum & Joost H.M. van Delft. (2009) A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo. Toxicology in Vitro 23:6, pages 1163-1169.
Crossref
Helena A. Soini, Donald Wiesler, Sachiko Koyama, Christophe Féron, Claude Baudoin & Milos V. Novotny. (2009) Comparison of Urinary Scents of Two Related Mouse Species, Mus spicilegus and Mus domesticus. Journal of Chemical Ecology 35:5, pages 580-589.
Crossref
Stefanie D. Krämer & Bernard Testa. (2008) The Biochemistry of Drug Metabolism – An Introduction. Chemistry & Biodiversity 5:12, pages 2465-2578.
Crossref
Filip Fratev & Emilio Benfenati. (2008) A combination of 3D-QSAR, docking, local-binding energy (LBE) and GRID study of the species differences in the carcinogenicity of benzene derivatives chemicals. Journal of Molecular Graphics and Modelling 27:2, pages 147-160.
Crossref
S. Visoni, N. Meireles, L. Monteiro, A. Rossini & L.F.R. Pinto. (2008) Different modes of inhibition of mouse Cyp2a5 and rat CYP2A3 by the food-derived 8-methoxypsoralen. Food and Chemical Toxicology 46:3, pages 1190-1195.
Crossref
Dariusz Pogocki, Tomasz Ruman, Magdalena Danilczuk, Marek Danilczuk, Monika Celuch & Elżbieta Wałajtys-Rode. (2007) Application of nicotine enantiomers, derivatives and analogues in therapy of neurodegenerative disorders. European Journal of Pharmacology 563:1-3, pages 18-39.
Crossref
David F.V. Lewis, Yuko Ito & Brian G. Lake. (2006) Metabolism of coumarin by human P450s: A molecular modelling study. Toxicology in Vitro 20:2, pages 256-264.
Crossref
Robert P Hunter, MaryAnn Radlinsky, David E Koch, Matthew Corse, Marie A. Pellerin & Jennifer Halstead. (2005) Plasma pharmacokinetics and synovial fluid concentrations after oral administration of single and multiple doses of celecoxib in Greyhounds. American Journal of Veterinary Research 66:8, pages 1441-1445.
Crossref
Mette T. Skaanild & Christian Friis. (2005) Porcine CYP2A Polymorphisms and Activity. Basic & Clinical Pharmacology & Toxicology 97:2, pages 115-121.
Crossref
Mary Beth GenterKathleen H. Goss & Joanna Groden. (2016) Strain-Specific Effects of Alachlor on Murine Olfactory Mucosal Responses. Toxicologic Pathology 32:6, pages 719-725.
Crossref
D.F.V. Lewis, B.G. Lake, M. Dickins & P.S. Goldfarb. (2003) Homology modelling of CYP2A6 based on the CYP2C5 crystallographic template: enzyme–substrate interactions and QSARs for binding affinity and inhibition. Toxicology in Vitro 17:2, pages 179-190.
Crossref
David F. V. Lewis. (2003) Quantitative structure–activity relationships (QSARs) within the cytochrome P450 system: QSARs describing substrate binding, inhibition and induction of P450s. InflammoPharmacology 11:1, pages 43-73.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.