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Xenobiotica
the fate of foreign compounds in biological systems
Volume 32, 2002 - Issue 7
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Research Article

Sulfation of R(--)-apomorphine in the human liver and duodenum, and its inhibition by mefenamic acid, salicylic acid and quercetin

M. Vietri Department of Neurosciences, Section of Pharmacology, Via Roma 55, I-56126 Pisa, Italy
,
F. Vaglini Department of Oncology, Section of Surgery, Cisanello Hospital at the University of Pisa, I-56124 Cisanello, Pisa, Italy
,
A. Pietrabissa Department of Surgery, Medical School, Via Roma 55, I-56126 Pisa, Italy
,
R. Spisni Department of Neurosciences, Section of Pharmacology, Via Roma 55, I-56126 Pisa, Italy
,
F. Mosca Department of Oncology, Section of Surgery, Cisanello Hospital at the University of Pisa, I-56124 Cisanello, Pisa, Italy
&
G. M. Pacifici Department of Surgery, Medical School, Via Roma 55, I-56126 Pisa, Italy
Pages 587-594 | Published online: 22 Sep 2008

Citations (13)

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Read on this site (3)

Margaret O. James & Sriram Ambadapadi. (2013) Interactions of cytosolic sulfotransferases with xenobiotics. Drug Metabolism Reviews 45:4, pages 401-414.
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Rainer Cermak. (2008) Effect of dietary flavonoids on pathways involved in drug metabolism. Expert Opinion on Drug Metabolism & Toxicology 4:1, pages 17-35.
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N. L. Thomas & M. W. H. Coughtrie. (2003) Sulfation of apomorphine by human sulfotransferases: evidence of a major role for the polymorphic phenol sulfotransferase, SULT1A1. Xenobiotica 33:11, pages 1139-1148.
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Articles from other publishers (10)

Yan Rong & Tony K.L. Kiang. (2021) Characterization of human sulfotransferases catalyzing the formation of p-cresol sulfate and identification of mefenamic acid as a potent metabolism inhibitor and potential therapeutic agent for detoxification. Toxicology and Applied Pharmacology 425, pages 115553.
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Manon Auffret, Sophie Drapier & Marc Vérin. (2018) Pharmacological Insights into the Use of Apomorphine in Parkinson’s Disease: Clinical Relevance. Clinical Drug Investigation 38:4, pages 287-312.
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Ting Wang, Ian Cook & Thomas S. Leyh. (2017) The NSAID allosteric site of human cytosolic sulfotransferases. Journal of Biological Chemistry 292:49, pages 20305-20312.
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Ian Cook, Ting Wang, Charles N. Falany & Thomas S. Leyh. (2015) The Allosteric Binding Sites of Sulfotransferase 1A1. Drug Metabolism and Disposition 43:3, pages 418-423.
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Zachary E. Tibbs, Katie Jo Rohn-Glowacki, Frank Crittenden, Amber L. Guidry & Charles N. Falany. (2015) Structural plasticity in the human cytosolic sulfotransferase dimer and its role in substrate selectivity and catalysis. Drug Metabolism and Pharmacokinetics 30:1, pages 3-20.
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Priya Batra & Anil K. Sharma. (2013) Anti-cancer potential of flavonoids: recent trends and future perspectives. 3 Biotech 3:6, pages 439-459.
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Sarah Egert & Gerald Rimbach. (2011) Which Sources of Flavonoids: Complex Diets or Dietary Supplements?. Advances in Nutrition 2:1, pages 8-14.
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Christopher Kohl. 2008. Drug Bioavailability. Drug Bioavailability 333 357 .
Gian Maria Pacifici. 2005. Human Cytosolic Sulfotransferases. Human Cytosolic Sulfotransferases 157 177 .
Kenneth W. Bentley. (2004) β-Phenylethylamines and the isoquinoline alkaloids. Nat. Prod. Rep. 21:3, pages 395-424.
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