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Xenobiotica
the fate of foreign compounds in biological systems
Volume 33, 2003 - Issue 10
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Research Article

Mechanism-based inhibition of CYP activities in rat liver by fluoxetine and structurally similar alkylamines

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Pages 973-987 | Received 29 Jan 2003, Published online: 22 Sep 2008

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Agnieszka Potęga, Barbara Fedejko-Kap & Zofia Mazerska. (2016) Mechanism-based inactivation of human cytochrome P450 1A2 and 3A4 isoenzymes by anti-tumor triazoloacridinone C-1305. Xenobiotica 46:12, pages 1056-1065.
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Robert J Riley, Ken Grime & Richard Weaver. (2007) Time-dependent CYP inhibition. Expert Opinion on Drug Metabolism & Toxicology 3:1, pages 51-66.
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Włladyslława Anna Daniel. (2005) The influence of long-term treatment with psychotropic drugs on cytochrome P450: the involvement of different mechanisms. Expert Opinion on Drug Metabolism & Toxicology 1:2, pages 203-217.
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Articles from other publishers (17)

DAN A. ROCK & LARRY C. WIENKERS. 2022. Drug Metabolism Handbook. Drug Metabolism Handbook 465 526 .
Władysława A. Daniel, Ewa Bromek, Przemysław J. Danek & Anna Haduch. (2022) The mechanisms of interactions of psychotropic drugs with liver and brain cytochrome P450 and their significance for drug effect and drug-drug interactions. Biochemical Pharmacology 199, pages 115006.
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John T. Barr, Zhican Wang, Xiaoshan Min, Henry J. Wienkers, Brooke M. Rock, Dan A. Rock & Larry C. Wienkers. (2020) Mechanistic Studies of Cytochrome P450 3A4 Time-Dependent Inhibition Using Two Cysteine-Targeting Electrophiles. Drug Metabolism and Disposition 48:6, pages 508-514.
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Mengbi Yang, Jiang Ma, Jianqing Ruan, Yang Ye, Peter Pi-Cheng Fu & Ge Lin. (2019) Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids. Archives of Toxicology 93:8, pages 2197-2209.
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Marta Kot, Anna Haduch, Mariusz Papp & Władysława A. Daniel. (2017) The Effect of Chronic Treatment with Lurasidone on Rat Liver Cytochrome P450 Expression and Activity in the Chronic Mild Stress Model of Depression. Drug Metabolism and Disposition 45:12, pages 1336-1344.
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Gabriela V. Aguirre-Martínez, Helena C. Reinardy, M. Laura Martín-Díaz & Theodore B. Henry. (2017) Response of gene expression in zebrafish exposed to pharmaceutical mixtures: Implications for environmental risk. Ecotoxicology and Environmental Safety 142, pages 471-479.
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Agnieszka Potęga, Barbara Fedejko-Kap & Zofia Mazerska. (2016) Imidazoacridinone antitumor agent C-1311 as a selective mechanism-based inactivator of human cytochrome P450 1A2 and 3A4 isoenzymes. Pharmacological Reports 68:4, pages 663-670.
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Jacek Wójcikowski, Anna Haduch & Władysława Anna Daniel. (2013) Effect of antidepressant drugs on cytochrome P450 2C11 (CYP2C11) in rat liver. Pharmacological Reports 65:5, pages 1247-1255.
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Joanna E. Barbara, Faraz Kazmi, Andrew Parkinson & David B. Buckley. (2013) Metabolism-Dependent Inhibition of CYP3A4 by Lapatinib: Evidence for Formation of a Metabolic Intermediate Complex with a Nitroso/Oxime Metabolite Formed via a Nitrone Intermediate. Drug Metabolism and Disposition 41:5, pages 1012-1022.
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Shuang Fu, Anthony Rowe & Iqbal Ramzan. (2012) Kavalactone Metabolism in Rat Liver Microsomes. Phytotherapy Research 26:7, pages 1057-1061.
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Dan Rock & Larry C. Wienkers. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia 1 56 .
Emilija Makaji, Cristina S. Trambitas, Pamela Shen, Alison C. Holloway & Denis J. Crankshaw. (2010) Effects of Cytochrome P450 Inhibitors on the Biotransformation of Fluorogenic Substrates by Adult Male Rat Liver Microsomes and cDNA-Expressed Rat Cytochrome P450 Isoforms. Toxicological Sciences 113:2, pages 293-304.
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Dan Rock & Larry C. Wienkers. 2009. Drug Metabolism Handbook. Drug Metabolism Handbook 479 534 .
Thomas M. Polasek & John O. Miners. (2008) Time-dependent inhibition of human drug metabolizing cytochromes P450 by tricyclic antidepressants. British Journal of Clinical Pharmacology 65:1, pages 87-97.
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W.A. Daniel, A. Haduch, M. Syrek & J. Boksa. (2006) Direct and indirect interactions between antidepressant drugs and CYP2C6 in the rat liver during long-term treatment. European Neuropsychopharmacology 16:8, pages 580-587.
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Dermot F. McGinnity, Amanda J. Berry, Jane R. Kenny, Ken Grime & Robert J. Riley. (2006) EVALUATION OF TIME-DEPENDENT CYTOCHROME P450 INHIBITION USING CULTURED HUMAN HEPATOCYTES. Drug Metabolism and Disposition 34:8, pages 1291-1300.
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A. Haduch, J. W?jcikowski & W.A. Daniel. (2006) The effect of tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs) and newer antidepressant drugs on the activity and level of rat CYP3A. European Neuropsychopharmacology 16:3, pages 178-186.
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