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Xenobiotica
the fate of foreign compounds in biological systems
Volume 33, 2003 - Issue 11
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Research Article

Transcriptional regulation of cytochrome P4503A4 gene expression: effects of inherited mutations in the 5′-flanking region

H. Hamzeiy Molecular Toxicology Group, School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UKCorrespondence[email protected]
,
V. Bombail Molecular Toxicology Group, School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK
,
N. Plant Molecular Toxicology Group, School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK
,
G. Gibson Molecular Toxicology Group, School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK
&
P. Goldfarb Molecular Toxicology Group, School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, UK
Pages 1085-1095 | Received 01 Jun 2003, Published online: 22 Sep 2008

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G. Gordon Gibson, Anna Phillips, Sihem Aouabdi, Kate Plant & Nick Plant. (2006) Transcriptional Regulation of the Human Pregnane-X Receptor. Drug Metabolism Reviews 38:1-2, pages 31-49.
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Articles from other publishers (6)

Marianthi Georgitsi, Branka Zukic, Sonja Pavlovic & George P Patrinos. (2011) Transcriptional regulation and pharmacogenomics. Pharmacogenomics 12:5, pages 655-673.
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SD Baker, J Verweij, GA Cusatis, RH van Schaik, S Marsh, SJ Orwick, RM Franke, S Hu, EG Schuetz, V Lamba, WA Messersmith, AC Wolff, MA Carducci & A Sparreboom. (2008) Pharmacogenetic Pathway Analysis of Docetaxel Elimination. Clinical Pharmacology & Therapeutics 85:2, pages 155-163.
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P.C. Das, T.M. Streit, Y. Cao, R.L. Rose, N. Cherrington, M.K. Ross, A.D. Wallace & E. Hodgson. (2008) Pyrethroids: Cytotoxicity and Induction of CYP Isoforms in Human Hepatocytes. Drug Metabolism and Drug Interactions 23:3-4.
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Cristina Rodríguez-Antona, Jane G. Sayi, Lars L. Gustafsson, Leif Bertilsson & Magnus Ingelman-Sundberg. (2005) Phenotype–genotype variability in the human CYP3A locus as assessed by the probe drug quinine and analyses of variant CYP3A4 alleles. Biochemical and Biophysical Research Communications 338:1, pages 299-305.
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Charnita Zeigler-Johnson, Tara Friebel, Amy H. Walker, Yiting Wang, Elaine Spangler, Saarene Panossian, Margerie Patacsil, Richard Aplenc, Alan J. Wein, S. Bruce Malkowicz & Timothy R. Rebbeck. (2004) CYP3A4 , CYP3A5 , and CYP3A43 Genotypes and Haplotypes in the Etiology and Severity of Prostate Cancer . Cancer Research 64:22, pages 8461-8467.
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Timothy R. Rebbeck, Margaret Spitz & Xifeng Wu. (2004) Assessing the function of genetic variants in candidate gene association studies. Nature Reviews Genetics 5:8, pages 589-597.
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