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Xenobiotica
the fate of foreign compounds in biological systems
Volume 33, 2003 - Issue 9
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Research Article

Evaluation of the role of the asialoglycoprotein receptor in the clearance of UK-279,276 (recombinant neutrophil inhibitory factor)

R. Webster Department of Pharmacokinetics Dynamics and Metabolism Pfizer Global Research and Development Sandwich CT13 9NJ UK
,
J. Phipps Department of Pharmacokinetics Dynamics and Metabolism Pfizer Global Research and Development Sandwich CT13 9NJ UK
,
R. Hyland Department of Pharmacokinetics Dynamics and Metabolism Pfizer Global Research and Development Sandwich CT13 9NJ UK
&
D. Walker Department of Pharmacokinetics Dynamics and Metabolism Pfizer Global Research and Development Sandwich CT13 9NJ UK
Pages 945-956 | Published online: 22 Sep 2008

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R. Webster, A. Edgington, J. Phipps & D. Walker. (2006) Pharmacokinetics and clearance processes of UK-279,276 (rNIF) in rat and dog: Comparison with human data. Xenobiotica 36:4, pages 341-349.
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Articles from other publishers (4)

Sandra Wymann, Marcel Mischnik, David Leong, Subhajit Ghosh, Xiahui Tan, Helen Cao, Benjamin Kuehnemuth, Glenn A. Powers, Partho Halder, Mitchell J. de Souza, Hannah S. James, Vesna Tomasetig, Holger Lind, Paolo Rossato, Catherine M. Owczarek, Saw Yen Ow, Steven K. Dower, Adriana Baz Morelli, Tony Rowe & Matthew P. Hardy. (2022) Sialylation-dependent pharmacokinetics and differential complement pathway inhibition are hallmarks of CR1 activity in vivo . Biochemical Journal 479:9, pages 1007-1030.
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Amita Datta-Mannan, Lihua Huang, Jennifer Pereira, Benjamin Yaden, Andrew Korytko & Johnny E. Croy. (2015) Insights into the Impact of Heterogeneous Glycosylation on the Pharmacokinetic Behavior of Follistatin-Fc–Based Biotherapeutics. Drug Metabolism and Disposition 43:12, pages 1882-1890.
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Scott Marshall, Fiona Macintyre, Ian James, Michael Krams & Niclas E Jonsson. (2006) Role of Mechanistically-Based Pharmacokinetic/Pharmacodynamic Models in Drug Development. Clinical Pharmacokinetics 45:2, pages 177-197.
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E. Niclas Jonsson, Fiona Macintyre, Ian James, Michael Krams & Scott Marshall. (2005) Bridging the Pharmacokinetics and Pharmacodynamics of UK-279,276 Across Healthy Volunteers and Stroke Patients Using a Mechanistically Based Model for Target-Mediated Disposition. Pharmaceutical Research 22:8, pages 1236-1246.
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