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Xenobiotica
the fate of foreign compounds in biological systems
Volume 33, 2003 - Issue 11
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Research Article

Pharmacokinetic analysis of factors determining elimination pathways for sulfate and glucuronide metabolites of xenobiotics II: Studies with isolated perfused rat liver

K. Higaki Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University, Okayama 700-8530, JapanCorrespondence[email protected]
,
M Ishii Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University, Okayama 700-8530, Japan
,
H. Esumi Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University, Okayama 700-8530, Japan
,
M. Kanayama Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University, Okayama 700-8530, Japan
,
K.-I. Ogawara Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University, Okayama 700-8530, Japan
&
T. Kimura Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University, Okayama 700-8530, Japan
Pages 1097-1108 | Received 02 May 2003, Published online: 22 Sep 2008

Citations (6)

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Read on this site (2)

Naoki Kamada, Keigo Yamada, Masaaki Odomi, Tadashi Mukai, Toru Nishibayashi, Ken-ichi Ogawara, Toshikiro Kimura & Kazutaka Higaki. (2011) Sex differences in pharmacokinetics of cilostazol in rats. Xenobiotica 41:10, pages 903-913.
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C. Nishida, K.-I. Ogawara, T. Kimura & K. Higaki. (2004) Pharmacokinetic analysis of factors determining elimination pathways for sulfate and glucuronide metabolites of xenobiotics. iii: mechanisms for sinusoidal efflux of 4-methylumbelliferone sulfate. Xenobiotica 34:5, pages 439-448.
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Articles from other publishers (4)

Keita Yamanouchi, Tomoki Ishimaru, Takuya Kakuno, Yuki Takemoto, Sho Kawatsu, Keiji Kondo, Masato Maruyama & Kazutaka Higaki. (2023) Improvement and characterization of oral absorption behavior of clofazimine by SNEDDS: Quantitative evaluation of extensive lymphatic transport. European Journal of Pharmaceutics and Biopharmaceutics 187, pages 141-155.
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Chikako Imada, Takuma Takahashi, Makoto Kuramoto, Kazufumi Masuda, Ken-ichi Ogawara, Akira Sato, Yusuke Wataya, Hye-Sook Kim & Kazutaka Higaki. (2015) Improvement of Oral Bioavailability of N-251, a Novel Antimalarial Drug, by Increasing Lymphatic Transport with Long-Chain Fatty Acid-Based Self-Nanoemulsifying Drug Delivery System. Pharmaceutical Research.
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Hirotaka Miyamoto, Satoshi Matsueda, Kotaro Komori, Shintaro Fumoto, Mikiro Nakashima, Naoki Yoshikawa, Haruna Hirata, Kenta Shimokawa, Yuichi Ohwaki & Koyo Nishida. (2013) Evaluation for effect of hypothermia on the disposition of 4-nitrophenol in rats by in-vitro metabolism study and rat liver perfusion system. Journal of Pharmacy and Pharmacology 65:10, pages 1536-1540.
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Pallabi Mitra & Kenneth L. Audus. (2010) MRP isoforms and BCRP mediate sulfate conjugate efflux out of BeWo cells. International Journal of Pharmaceutics 384:1-2, pages 15-23.
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