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Xenobiotica
the fate of foreign compounds in biological systems
Volume 33, 2003 - Issue 12
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Research Article

‘Open access’ generic method for continuous determination of major human CYP450 probe substrates/metabolites and its application in drug metabolism studies

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Pages 1233-1245 | Received 17 Jul 2003, Published online: 22 Sep 2008

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Huaqiao Tang, Nana Long, Min Dai, Lin Lin, Jianlong Li, Fenghui Sun & Lijuan Guo. (2018) Effect of citral on mouse hepatic cytochrome P450 enzymes. Pharmaceutical Biology 56:1, pages 337-343.
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Hua-Qiao Tang, Min Xu, Qian Rong, Ru-Wen Jin, Qi-Ji Liu & Ying-Lun Li. (2016) The effect of ZnO nanoparticles on liver function in rats. International Journal of Nanomedicine 11, pages 4275-4285.
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S. Muzeeb, M. K. Pasha, S. J. S. Basha, R. Mullangi & N. R. Srinivas. (2005) Effect of 1-aminobenzotriazole on the in vitro metabolism and single-dose pharmacokinetics of chlorzoxazone, a selective CYP2E1 substrate in Wistar rats. Xenobiotica 35:8, pages 825-838.
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R Bhamidipati, S Mujeeb, P. V Dravid, A. A Khan, S. K Singh, Y. K Rao, R Mullangi & N. R Srinivas. (2005) Pre-clinical assessment of DRF 4367, a novel COX-2 inhibitor: Evaluation of pharmacokinetics, absolute oral bioavailability and metabolism in mice and comparative inter-species in vitro metabolism. Xenobiotica 35:3, pages 253-271.
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Articles from other publishers (10)

Huaqiao Tang, Min Xu, Jie Luo, Ling Zhao, Gang Ye, Fei Shi, Cheng Lv, Helin Chen, Yanyan Wang & Yinglun Li. (2019) Liver toxicity assessments in rats following sub-chronic oral exposure to copper nanoparticles. Environmental Sciences Europe 31:1.
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Huaqiao Tang, Min Xu, Fei Shi, Gang Ye, Cheng Lv, Jie Luo, Ling Zhao & Yinglun Li. (2018) Effects and Mechanism of Nano-Copper Exposure on Hepatic Cytochrome P450 Enzymes in Rats. International Journal of Molecular Sciences 19:7, pages 2140.
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Sandeep Kumar Vishwakarma, Avinash Bardia, Chandrakala Lakkireddy, Raju Nagarapu, Md Aejaz Habeeb & Aleem Ahmed Khan. (2018) Bioengineered humanized livers as better three-dimensional drug testing model system. World Journal of Hepatology 10:1, pages 22-33.
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Jan Juřica, Jiří Konečný, Lucia Zendulková Zahradníková & Josef Tomandl. (2010) Simultaneous HPLC determination of tolbutamide, phenacetin and their metabolites as markers of cytochromes 1A2 and 2C6/11 in rat liver perfusate. Journal of Pharmaceutical and Biomedical Analysis 52:4, pages 557-564.
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J. N. Suresh Kumar, Prameela Devi, Lakshmi Narasu & Ramesh Mullangi. (2008) Effect of ciprofloxacin and ibuprofen on thein vitro Metabolism of rosiglitazone and oral pharmacokinetics of rosiglitazone in healthy human volunteers. European Journal of Drug Metabolism and Pharmacokinetics 33:4, pages 237-242.
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Syed Muzeeb, Shaik Jafar Sadik Basha, Dhanya Shashikumar, Ramesh Mullangi & Nuggehally R. Srinivas. (2006) Glucuronidation of DRF-6574, hydroxy metabolite of DRF-4367 (a novel COX-2 inhibitor) by pooled human liver, intestinal microsomes and recombinant human UDP-glucuronosyltransferases (UGT): Role of UGT1A1,1A3 and 1A8. European Journal of Drug Metabolism and Pharmacokinetics 31:4, pages 299-309.
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Nuggehally R. Srinivas. (2006) Applicability of bioanalysis of multiple analytes in drug discovery and development: review of select case studies including assay development considerations. Biomedical Chromatography 20:5, pages 383-414.
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Md. Khalid Pasha, Syed Muzeeb, Shaik Jafar Sadik Basha, Dhanya Shashikumar, Ramesh Mullangi & Nuggehally R. Srinivas. (2005) Analysis of five HMG‐CoA reductase inhibitors— atorvastatin, lovastatin, pravastatin, rosuvastatin and simvastatin: pharmacological, pharmacokinetic and analytical overview and development of a new method for use in pharmaceutical formulations analysis and in vitro metabolism studies . Biomedical Chromatography 20:3, pages 282-293.
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Naseem Begum Shakeel, Vijayalakshmi Venkateshan, Parveen, Adarsh K. Capoor, Mohammed Aejaz Habeeb, Ansar Ali Khan, Syed Muzeeb, N. V. S. Rao Mamidi, Aleem Ahmed Khan & Chittoor Mohammed Habibullah. (2005) Effect of ultraviolet B (302 nm) irradiation on viability, metabolic and detoxification functions of goat hepatocytes – in vitro study. Molecular and Cellular Biochemistry 277:1-2, pages 49-53.
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Olga V. Trubetskoy, Jasmin R. Gibson & Bryan D. Marks. (2005) Highly Miniaturized Formats for In Vitro Drug Metabolism Assays Using Vivid® Fluorescent Substrates and Recombinant Human Cytochrome P450 Enzymes. SLAS Discovery 10:1, pages 56-66.
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