Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 34, 2004 - Issue 11-12
157
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Identification of the cytochrome P450 enzymes involved in the metabolism of domperidone

, , , , &
Pages 1013-1023 | Received 07 Oct 2004, Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

. (2016) Abstract. Drug Metabolism Reviews 48:sup1, pages 28-157.
Read now
Amir S. Youssef, Henry P. Parkman & Swati Nagar. (2014) Domperidone interacts with pioglitazone but not with ondansetron via common CYP metabolism in vitro. Xenobiotica 44:9, pages 792-803.
Read now
Amir S. Youssef, Upendra A. Argikar, Murali Pathikonda, Henry P. Parkman & Swati Nagar. (2013) Identification of domperidone metabolites in plasma and urine of gastroparesis patients with LC–ESI-MS/MS. Xenobiotica 43:12, pages 1073-1083.
Read now
D. Ung, H. P. Parkman & S. Nagar. (2009) Metabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis. Xenobiotica 39:10, pages 749-756.
Read now

Articles from other publishers (17)

David Moreno Ajona, María Dolores Villar Martínez, Calvin Chan & Peter J. Goadsby. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology 548 589 .
Byeong Geun Song, Yeong Chan Lee, Yang Won Min, Kyunga Kim, Hyuk Lee, Hee Jung Son & Poong-Lyul Rhee. (2020) Risk of domperidone induced severe ventricular arrhythmia. Scientific Reports 10:1.
Crossref
Janneke M. Brussee, Elke H. J. Krekels, Elisa A. M. Calvier, Semra Palić, Amin Rostami-Hodjegan, Meindert Danhof, Jeffrey S. Barrett, Saskia N. de Wildt & Catherijne A. J. Knibbe. (2019) A Pediatric Covariate Function for CYP3A-Mediated Midazolam Clearance Can Scale Clearance of Selected CYP3A Substrates in Children. The AAPS Journal 21:5.
Crossref
Jake E. Thistle, Jessica L. Petrick, Baiyu Yang, Marie C. Bradley, Barry I. Graubard & Katherine A. McGlynn. (2018) Domperidone use and risk of primary liver cancer in the Clinical Practice Research Datalink. Cancer Epidemiology 55, pages 170-175.
Crossref
J. R. Giudicessi, M. J. Ackerman & M. Camilleri. (2018) Cardiovascular safety of prokinetic agents: A focus on drug‐induced arrhythmias. Neurogastroenterology & Motility 30:6.
Crossref
A. S. Youssef, H. P. Parkman & S. Nagar. (2015) Drug‐drug interactions in pharmacologic management of gastroparesis. Neurogastroenterology & Motility 27:11, pages 1528-1541.
Crossref
Ling Fang, Chao-Xian Lin, Zhi-Wei Zhu, Lin-Shu Zhao & Shu-Yao Zhang. (2014) Elucidation of in vitro phase I metabolites of droperidol using UPLC-QTOF MS. European Journal of Drug Metabolism and Pharmacokinetics 40:1, pages 111-114.
Crossref
Dany Patoine, Michaël Petit, Sylvie Pilote, Frédéric Picard, Benoit Drolet & Chantale Simard. (2014) Modulation of CYP 3a expression and activity in mice models of type 1 and type 2 diabetes . Pharmacology Research & Perspectives 2:6.
Crossref
Juefang Ding. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 4 .
Dany Patoine, Xavier Levac, Sylvie Pilote, Benoit Drolet & Chantale Simard. (2013) Decreased CYP3A Expression and Activity in Guinea Pig Models of Diet-Induced Metabolic Syndrome: Is Fatty Liver Infiltration Involved?. Drug Metabolism and Disposition 41:5, pages 952-957.
Crossref
Veronique Michaud & Jacques Turgeon. (2013) Domperidone and Sudden Cardiac Death. Journal of Cardiovascular Pharmacology 61:3, pages 215-217.
Crossref
Henry P. Parkman, Michael R. Jacobs, Anurag Mishra, Jessica A. Hurdle, Priyanka Sachdeva, John P. Gaughan & Evgeny Krynetskiy. (2010) Domperidone Treatment for Gastroparesis: Demographic and Pharmacogenetic Characterization of Clinical Efficacy and Side-Effects. Digestive Diseases and Sciences 56:1, pages 115-124.
Crossref
Akihiro Hisaka, Yoshiyuki Ohno, Takehito Yamamoto & Hiroshi Suzuki. (2010) Prediction of pharmacokinetic drug–drug interaction caused by changes in cytochrome P450 activity using in vivo information. Pharmacology & Therapeutics 125:2, pages 230-248.
Crossref
Frederique Fenneteau, Patrick Poulin & Fahima Nekka. (2010) Physiologically Based Predictions of the Impact of Inhibition of Intestinal and Hepatic Metabolism on Human Pharmacokinetics of CYP3A Substrates. Journal of Pharmaceutical Sciences 99:1, pages 486-514.
Crossref
Benoît Drolet, Chantale Simard, Laimonis Gailis & Pascal Daleau. (2007) Ischemic, genetic and pharmacological origins of cardiac arrhythmias: The contribution of the Quebec Heart Institute. Canadian Journal of Cardiology 23, pages 15B-22B.
Crossref
Yi-fan ZHANG, Xiao-yan CHEN, Xiao-jian DAI, Yi-ni ZHANG, Qi-zhi LIU, Hua-ling YU & Da-fang ZHONG. (2007) Influence of omeprazole on pharmacokinetics of domperidone given as free base and maleate salt in healthy Chinese patients. Acta Pharmacologica Sinica 28:8, pages 1243-1246.
Crossref
Veronique Michaud, Chantal Simard & Jacques Turgeon. (2007) An improved HPLC assay with fluorescence detection for the determination of domperidone and three major metabolites for application to in vitro drug metabolism studies. Journal of Chromatography B 852:1-2, pages 611-616.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.