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Xenobiotica
the fate of foreign compounds in biological systems
Volume 34, 2004 - Issue 5
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Research Article

Model for the drug–drug interaction responsible for CYP3A enzyme inhibition. II: establishment and evaluation of dexamethasone-pretreated female rats

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Pages 403-413 | Received 10 Oct 2003, Published online: 22 Sep 2008

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Ragini Vuppugalla, Yueping Zhang, Shu Chang, A. David Rodrigues & Punit H. Marathe. (2012) Impact of nonlinear midazolam pharmacokinetics on the magnitude of the midazolam-ketoconazole interaction in rats. Xenobiotica 42:11, pages 1058-1068.
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N. Sekiguchi, M. Kato, M. Takada, H. Watanabe, A. Higashida, S. Sakai, M. Ishigai & Y. Aso. (2008) approach for the evaluation of mechanism-based inhibition of cytochrome P450 3A in rats. Xenobiotica 38:4, pages 368-381.
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Kevin L. Salyers & Yang Xu. 2012. ADME‐Enabling Technologies in Drug Design and Development. ADME‐Enabling Technologies in Drug Design and Development 253 276 .
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Xin Wang & John H. K. Yeung. (2011) Effects of Salvia miltiorrhiza Extract on the Liver CYP3A Activity in Humans and Rats . Phytotherapy Research 25:11, pages 1653-1659.
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Xin Wang & John H.K. Yeung. (2011) Inhibitory effect of tanshinones on rat CYP3A2 and CYP2C11 activity and its structure-activity relationship. Fitoterapia 82:4, pages 539-545.
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Xin Wang, Ching Mei Cheung, Wayne Y.W. Lee, Penelope M.Y. Or & John H.K. Yeung. (2010) Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro. Phytomedicine 17:11, pages 868-875.
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Stephen Fowler & Hongjian Zhang. (2008) In Vitro Evaluation of Reversible and Irreversible Cytochrome P450 Inhibition: Current Status on Methodologies and their Utility for Predicting Drug–Drug Interactions. The AAPS Journal 10:2, pages 410-424.
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Sudhir N. Umathe, Pankaj V. Dixit, Vijendra kumar, Kuldeep U. Bansod & Manish M. Wanjari. (2008) Quercetin pretreatment increases the bioavailability of pioglitazone in rats: Involvement of CYP3A inhibition. Biochemical Pharmacology 75:8, pages 1670-1676.
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Yi-Hua Jan, Vladimir Mishin, Christine M. Busch & Paul E. Thomas. (2006) Generation of specific antibodies and their use to characterize sex differences in four rat P450 3A enzymes following vehicle and pregnenolone 16α-carbonitrile treatment. Archives of Biochemistry and Biophysics 446:2, pages 101-110.
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