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Xenobiotica
the fate of foreign compounds in biological systems
Volume 34, 2004 - Issue 5
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Research Article

Potential of pranlukast and zafirlukast in the inhibition of human liver cytochrome P450 enzymes

K. H. Liu Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine and Clinical Pharmacology Center, Busan Paik Hospital, Busan 614-735, KoreaCorrespondence[email protected]
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Y. M. Lee Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine and Clinical Pharmacology Center, Busan Paik Hospital, Busan 614-735, Korea
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J. H. Shon Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine and Clinical Pharmacology Center, Busan Paik Hospital, Busan 614-735, Korea
,
M. J. Kim Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine and Clinical Pharmacology Center, Busan Paik Hospital, Busan 614-735, Korea
,
S. S. Lee Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine and Clinical Pharmacology Center, Busan Paik Hospital, Busan 614-735, Korea
,
Y. R. Yoon Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine and Clinical Pharmacology Center, Busan Paik Hospital, Busan 614-735, Korea
,
I. J. Cha Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine and Clinical Pharmacology Center, Busan Paik Hospital, Busan 614-735, Korea
&
J. G. Shin Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine and Clinical Pharmacology Center, Busan Paik Hospital, Busan 614-735, Korea
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Pages 429-438 | Received 06 Nov 2003, Published online: 22 Sep 2008

Citations (14)

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Read on this site (2)

M. D. Lee, E. Ayanoglu & L. Gong. (2006) Drug-induced changes in P450 enzyme expression at the gene expression level: A new dimension to the analysis of drug–drug interactions. Xenobiotica 36:10-11, pages 1013-1080.
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K. H. Liu, M. J. Kim, J. H. Shon, Y. S. Moon, S. Y. Seol, W Kang, I. J. Cha & J. G. Shin. (2005) Stereoselective inhibition of cytochrome P450 forms by lansoprazole and omeprazole in vitro. Xenobiotica 35:1, pages 27-38.
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Articles from other publishers (12)

Erika Tamai, Takeo Yasu, Eri Hikita & Mikio Shirota. (2023) Elevated Prothrombin Time and International Normalized Ratio Caused by Drug–Drug Interactions Between Warfarin and Pranlukast. American Journal of Therapeutics 30:3, pages e302-e303.
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Wei-Jie Li, Yun Zhao, Yuan Gao, Ling-Ling Dong, Yin-Fang Wu, Zhi-Hua Chen & Hua-Hao Shen. (2021) Lipid metabolism in asthma: Immune regulation and potential therapeutic target. Cellular Immunology 364, pages 104341.
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Boram Lee, Zhexue Wu, Sang Hyun Sung, Taeho Lee, Kyung-Sik Song, Min Young Lee & Kwang-Hyeon Liu. (2014) Potential of decursin to inhibit the human cytochrome P450 2J2 isoform. Food and Chemical Toxicology 70, pages 94-99.
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Boram Lee, Wonku Kang, Jongcheol Shon, Ki Hun Park, Kyung-Sik Song & Kwang-Hyeon Liu. (2014) Potential of 4′-(p-toluenesulfonylamide)-4-hydroxychalcone to inhibit the human cytochrome P450 2J2 isoform. Journal of the Korean Society for Applied Biological Chemistry 57:1, pages 31-34.
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Chong-Zhen Qin, Xian Ren, Zhi-Rong Tan, Yao Chen, Ji-Ye Yin, Jing Yu, Jian Qu, Hong-Hao Zhou & Zhao-Qian Liu. (2014) A high-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography-tandem mass spectrometry . Biomedical Chromatography 28:2, pages 197-203.
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H. W. Lee, D. W. Kim, P. B. Phapale, M. -S. Lim, J. Park, J. J. Seo, K. M. Park, Y. -K. Park & Y. -R. Yoon. (2011) In vitro inhibitory effects of Wen-pi-tang-Hab-Wu-ling-san on human cytochrome P450 isoforms. Journal of Clinical Pharmacy and Therapeutics 36:4, pages 496-503.
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Kazuhiro YonedaIchiro MatsumotoFumitaka SutohRyunosuke HigashiKen-ichi NunoyaSusumu NakadeYasuyuki MiyataMikio Ogawa. (2009) In Vitro Metabolism and Inhibitory Effects of Pranlukast in Human Liver Microsomes. Biological and Pharmaceutical Bulletin 32:4, pages 688-693.
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Kyung-Ah Seo, Hyunmi Kim, Hei-Young Ku, Hee-Jeong Ahn, Soo-Jin Park, Soo Kyung Bae, Jae-Gook Shin & Kwang-Hyeon Liu. (2008) The monoterpenoids citral and geraniol are moderate inhibitors of CYP2B6 hydroxylase activity. Chemico-Biological Interactions 174:3, pages 141-146.
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Markus Joerger, Katharina Hartmann & Max Kuhn. 2007. 168 181 .
Hyunmi Kim, Yune-Jung Yoon, Ji-Hong Shon, In-June Cha, Jae-Gook Shin & Kwang-Hyeon Liu. (2006) INHIBITORY EFFECTS OF FRUIT JUICES ON CYP3A ACTIVITY. Drug Metabolism and Disposition 34:4, pages 521-523.
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K. H. Liu, M. J. Kim, B. H. Jeon, J. H. Shon, I. J. Cha, K. H. Cho, S. S. Lee & J. G. Shin. (2006) Inhibition of human cytochrome P450 isoforms and NADPH-CYP reductase in vitro by 15 herbal medicines, including Epimedii herba. Journal of Clinical Pharmacy and Therapeutics 31:1, pages 83-91.
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Min-Jung Kim, Hyojin Kim, In-June Cha, Jang-Su Park, Ji-Hong Shon, Kwang-Hyeon Liu & Jae-Gook Shin. (2005) High-throughput screening of inhibitory potential of nine cytochrome P450 enzymesin vitro using liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry 19:18, pages 2651-2658.
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