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Xenobiotica
the fate of foreign compounds in biological systems
Volume 35, 2005 - Issue 6
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Research Article

Usefulness of hepatocytes for evaluating the genetic polymorphism of CYP2D6 substrates

H. Komura Faculty of Pharmaceutical Sciences, Kinki University, Osaka, JapanCorrespondence[email protected]
&
M. Iwaki Faculty of Pharmaceutical Sciences, Kinki University, Osaka, Japan
Pages 575-587 | Received 31 Jan 2005, Published online: 22 Sep 2008

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Read on this site (1)

S. Uno, M. Uraki, H. Komura, H. Ikuta, A. Kawase & M. Iwaki. (2008) Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis. Xenobiotica 38:11, pages 1410-1421.
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Articles from other publishers (5)

Reiko Watanabe, Toshio Kawata, Shinya Ueda, Takumi Shinbo, Mitsuo Higashimori, Yayoi Natsume-Kitatani & Kenji Mizuguchi. (2022) Prediction of the Contribution Ratio of a Target Metabolic Enzyme to Clearance from Chemical Structure Information. Molecular Pharmaceutics 20:1, pages 419-426.
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Alexander V. LyubimovHiroshi Komura & Masahiro Iwaki. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 41 .
Manoli Vourvahis & Angela D. M. Kashuba. (2012) Mechanisms of Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Ritonavir‐Enhanced Tipranavir. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 27:6, pages 888-909.
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Li Li, Run-Mei Pan, Todd D. Porter, Neil S. Jensen, Paul Silber, Guy Russo, John A. Tine, John Heim, Barbara Ring & Peter J. Wedlund. (2006) NEW CYTOCHROME P450 2D6*56 ALLELE IDENTIFIED BY GENOTYPE/PHENOTYPE ANALYSIS OF CRYOPRESERVED HUMAN HEPATOCYTES . Drug Metabolism and Disposition 34:8, pages 1411-1416.
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Nuggehally R. Srinivas. (2006) Drug disposition of chiral and achiral drug substrates metabolized by cytochrome P450 2D6 isozyme: case studies, analytical perspectives and developmental implications. Biomedical Chromatography 20:6-7, pages 466-491.
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