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Xenobiotica
the fate of foreign compounds in biological systems
Volume 35, 2005 - Issue 9
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Research Article

In vivo induction of human cytochrome P450 3A4 by rifabutin in chimeric mice with humanized liver

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Pages 863-875 | Received 16 May 2005, Published online: 22 Sep 2008

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Tao Li, Ruth T Yu, Annette R Atkins, Michael Downes, Robert H Tukey & Ronald M Evans. (2012) Targeting the pregnane X receptor in liver injury. Expert Opinion on Therapeutic Targets 16:11, pages 1075-1083.
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Upendra A Argikar, Otito F Iwuchukwu & Swati Nagar. (2008) Update on tools for evaluation of uridine diphosphoglucuronosyltransferase polymorphisms. Expert Opinion on Drug Metabolism & Toxicology 4:7, pages 879-894.
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C. Emoto, Y. Yamato, Y. Sato, H. Ohshita, M. Katoh, C. Tateno, T. Yokoi, K. Yoshizato & K. Iwasaki. (2008) Non-invasive method to detect induction of CYP3A4 in chimeric mice with a humanized liver. Xenobiotica 38:3, pages 239-248.
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Miki Katoh & Tsuyoshi Yokoi. (2007) Application of Chimeric Mice with Humanized Liver for Predictive ADME. Drug Metabolism Reviews 39:1, pages 145-157.
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Jan L Wahlstrom, Dan A Rock, J Greg Slatter & Larry C Wienkers. (2006) Advances in predicting CYP-mediated drug interactions in the drug discovery setting. Expert Opinion on Drug Discovery 1:7, pages 677-691.
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Sandra Grañana-Castillo, Angharad Williams, Thao Pham, Saye Khoo, Daryl Hodge, Asangaedem Akpan, Rachel Bearon & Marco Siccardi. (2023) General Framework to Quantitatively Predict Pharmacokinetic Induction Drug–Drug Interactions Using In Vitro Data. Clinical Pharmacokinetics 62:5, pages 737-748.
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Anna Zerdoug, Marc Le Vée, Shotaro Uehara, Béatrice Lopez, Christophe Chesné, Hiroshi Suemizu & Olivier Fardel. (2022) Contribution of Humanized Liver Chimeric Mice to the Study of Human Hepatic Drug Transporters: State of the Art and Perspectives. European Journal of Drug Metabolism and Pharmacokinetics 47:5, pages 621-637.
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Yoichi Naritomi, Seigo Sanoh & Shigeru Ohta. (2018) Chimeric mice with humanized liver: Application in drug metabolism and pharmacokinetics studies for drug discovery. Drug Metabolism and Pharmacokinetics 33:1, pages 31-39.
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Masashi Uchida, Yoriko Tajima, Masakazu Kakuni, Yutaka Kageyama, Taro Okada, Eri Sakurada, Chise Tateno & Ryoji Hayashi. (2018) Organic Anion–Transporting Polypeptide (OATP)–Mediated Drug-Drug Interaction Study between Rosuvastatin and Cyclosporine A in Chimeric Mice with Humanized Liver. Drug Metabolism and Disposition 46:1, pages 11-19.
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Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai & K. Sandy Pang. (2017) Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models. Journal of Pharmacology and Experimental Therapeutics 360:1, pages 174-191.
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K. Samuelsson, N. Scheer, I. Wilson, C.R. Wolf & C.J. Henderson. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 130 149 .
Lifei Huang, Jiajun Liu, Xin Yu, Lei Shi, Jian Liu, Heping Xiao & Yi Huang. (2016) Drug-drug interactions between moxifloxacin and rifampicin based on pharmacokinetics in vivo in rats . Biomedical Chromatography 30:10, pages 1591-1598.
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Yoann Crabol, Emilie Catherinot, Nicolas Veziris, Vincent Jullien & Olivier Lortholary. (2016) Rifabutin: where do we stand in 2016?. Journal of Antimicrobial Chemotherapy 71:7, pages 1759-1771.
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Nico Scheer & Ian D. Wilson. (2016) A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity. Drug Discovery Today 21:2, pages 250-263.
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Markus von Schaewen, Gabriela Hrebikova & Alexander Ploss. 2016. Mouse Models for Drug Discovery. Mouse Models for Drug Discovery 79 101 .
Thomas J. Bateman, Vijay G.B. Reddy, Masakazu Kakuni, Yoshio Morikawa & Sanjeev Kumar. (2014) Application of Chimeric Mice with Humanized Liver for Study of Human-Specific Drug Metabolism. Drug Metabolism and Disposition 42:6, pages 1055-1065.
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Seigo Sanoh & Shigeru Ohta. (2014) Chimeric mice transplanted with human hepatocytes as a model for prediction of human drug metabolism and pharmacokinetics. Biopharmaceutics & Drug Disposition 35:2, pages 71-86.
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Markus Grompe & Stephen Strom. (2013) Mice With Human Livers. Gastroenterology 145:6, pages 1209-1214.
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Chunja Lee, Xinxin Ding & David S. Riddick. (2013) Downregulation of Mouse Hepatic CYP3A Protein by 3-Methylcholanthrene Does Not Require Cytochrome P450-Dependent Metabolism. Drug Metabolism and Disposition 41:10, pages 1782-1786.
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Alexander V. LyubimovAndrew Bessire, Kuresh Youdim, Susan Hurst & Caroline A. Lee. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 88 .
Maki Hasegawa, Harunobu Tahara, Ryo Inoue, Masakazu Kakuni, Chise Tateno & Junko Ushiki. (2012) Investigation of Drug-Drug Interactions Caused by Human Pregnane X Receptor-Mediated Induction of CYP3A4 and CYP2C Subfamilies in Chimeric Mice with a Humanized Liver. Drug Metabolism and Disposition 40:3, pages 474-480.
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Chie Emoto, Kazuhide IwasakiNorie Murayama & Hiroshi Yamazaki. (2011) Drug Metabolism and Toxicity in Chimeric Mice with Humanized Liver. Journal of Health Science 57:1, pages 22-27.
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Glenn H. Cantor. 2010. Predictive Toxicology in Drug Safety. Predictive Toxicology in Drug Safety 269 283 .
Michael Sinz, Sean Kim, Stephen Ferguson & Edward LeCluyse. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia 1 31 .
Paul A. Aristoff, George A. Garcia, Paul D. Kirchhoff & H.D. Hollis Showalter. (2010) Rifamycins – Obstacles and opportunities. Tuberculosis 90:2, pages 94-118.
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Stephen C. Strom, Julio Davila & Markus Grompe. 2010. Hepatocytes. Hepatocytes 491 509 .
Edward L. Lecluyse, Michael W. Sinz, Nicola Hewitt, Stephen S. Ferguson & Jasminder Sahi. 2009. Enzyme Inhibition in Drug Discovery and Development. Enzyme Inhibition in Drug Discovery and Development 265 314 .
Michael Sinz, Sean Kim, Stephen Ferguson & Edward Lecluyse. 2009. Drug Metabolism Handbook. Drug Metabolism Handbook 359 389 .
Michael Sinz, Gillian Wallace & Jasminder Sahi. (2008) Current Industrial Practices in Assessing CYP450 Enzyme Induction: Preclinical and Clinical. The AAPS Journal 10:2, pages 391-400.
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Miki Katoh, Chise Tateno, Katsutoshi Yoshizato & Tsuyoshi Yokoi. (2008) Chimeric mice with humanized liver. Toxicology 246:1, pages 9-17.
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Aaron T. Wright & Benjamin F. Cravatt. (2007) Chemical Proteomic Probes for Profiling Cytochrome P450 Activities and Drug Interactions In Vivo. Chemistry & Biology 14:9, pages 1043-1051.
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Miki Katoh, Toshiro Sawada, Yoshinori Soeno, Miki Nakajima, Chise Tateno, Katsutoshi Yoshizato & Tsuyoshi Yokoi. (2007) In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver. Journal of Pharmaceutical Sciences 96:2, pages 428-437.
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Hiroki Yoshitsugu, Masuhiro Nishimura, Chise Tateno, Miho Kataoka, Eiji Takahashi, Yoshinori Soeno, Katsutoshi Yoshizato, Tsuyoshi Yokoi & Shinsaku Naito. (2006) Evaluation of Human CYP1A2 and CYP3A4 mRNA Expression in Hepatocytes from Chimeric Mice with Humanized Liver. Drug Metabolism and Pharmacokinetics 21:6, pages 465-474.
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