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Paresh P. Chothe, Masanori Nakakariya, Charles J. Rotter, Philip Sandoval & Kimio Tohyama. (2021) Recent advances in drug transporter sciences: highlights from the year 2020. Drug Metabolism Reviews 53:3, pages 321-349.
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Keigo Nakayama, Soichiro Ito, Masahiro Suzuki, Hiroaki Takubo, Hiroshi Yamazaki & Yukihiro Nomura. (2019) Prediction of human pharmacokinetics of typical compounds by a physiologically based method using chimeric mice with humanized liver. Xenobiotica 49:4, pages 404-414.
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Seigo Sanoh, Yoichi Naritomi, Mami Fujimoto, Koya Sato, Akio Kawamura, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura & Shigeru Ohta. (2015) Predictability of plasma concentration–time curves in humans using single-species allometric scaling of chimeric mice with humanized liver. Xenobiotica 45:7, pages 605-614.
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Shigeyuki Kitamura & Kazumi Sugihara. (2014) Current status of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver. Xenobiotica 44:2, pages 123-134.
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John R. Foster, Garry Lund, Svetlana Sapelnikova, D. Lorne Tyrrell & Norman M. Kneteman. (2014) Chimeric rodents with humanized liver: bridging the preclinical/clinical trial gap in ADME/toxicity studies. Xenobiotica 44:2, pages 109-122.
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Katsutoshi Yoshizato & Chise Tateno. (2009) In vivo modeling of human liver for pharmacological study using humanized mouse. Expert Opinion on Drug Metabolism & Toxicology 5:11, pages 1435-1446.
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Upendra A Argikar, Otito F Iwuchukwu & Swati Nagar. (2008) Update on tools for evaluation of uridine diphosphoglucuronosyltransferase polymorphisms. Expert Opinion on Drug Metabolism & Toxicology 4:7, pages 879-894.
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Miki Katoh & Tsuyoshi Yokoi. (2007) Application of Chimeric Mice with Humanized Liver for Predictive ADME. Drug Metabolism Reviews 39:1, pages 145-157.
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Articles from other publishers (41)
Anna Zerdoug, Marc Le Vée, Shotaro Uehara, Béatrice Lopez, Christophe Chesné, Hiroshi Suemizu & Olivier Fardel. (2022) Contribution of Humanized Liver Chimeric Mice to the Study of Human Hepatic Drug Transporters: State of the Art and Perspectives. European Journal of Drug Metabolism and Pharmacokinetics 47:5, pages 621-637.
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Koya Sato, Seigo Sanoh, Yuji Ishida, Chise TatenoShigeru Ohta & Yaichiro Kotake. (2022) Assessment of metabolic activation of felbamate in chimeric mice with humanized liver in combination with <i>in vitro</i> metabolic assays. The Journal of Toxicological Sciences 47:7, pages 277-288.
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Yonghong Luo, Haocheng Lu, Daoquan Peng, Xiangbo Ruan, Yuqing Eugene Chen & Yanhong Guo. (2021) Liver‐humanized mice: A translational strategy to study metabolic disorders. Journal of Cellular Physiology 237:1, pages 489-506.
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Azusa Futatsugi, Yusuke Masuo & Yukio Kato. (2021) Effects of Probenecid on Hepatic and Renal Disposition of Hexadecanedioate, an Endogenous Substrate of Organic Anion Transporting Polypeptide 1B in Rats. Journal of Pharmaceutical Sciences 110:5, pages 2274-2284.
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Bo Feng, Rachel Pemberton, Wojciech Dworakowski, Zhengqi Ye, Craig Zetterberg, Guanyu Wang, Yoshio Morikawa & Sanjeev Kumar. (2021) Evaluation of the Utility of PXB Chimeric Mice for Predicting Human Liver Partitioning of Hepatic Organic Anion-Transporting Polypeptide Transporter Substrates. Drug Metabolism and Disposition 49:3, pages 254-264.
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Kaito Nihira, Ken-ichiro Nan-ya, Masakazu Kakuni, Yoko Ono, Yukitaka Yoshikawa, Toshio Ota, Masanori Hiura & Kouichi Yoshinari. (2019) Chimeric Mice With Humanized Livers Demonstrate Human-Specific Hepatotoxicity Caused by a Therapeutic Antibody Against TRAIL-Receptor 2/Death Receptor 5. Toxicological Sciences 167:1, pages 190-201.
Crossref
Crossref
Donna N. Douglas & Norman M. Kneteman. 2019. Hepatitis C Virus Protocols. Hepatitis C Virus Protocols
459
479
.
Masashi Uchida, Yoriko Tajima, Masakazu Kakuni, Yutaka Kageyama, Taro Okada, Eri Sakurada, Chise Tateno & Ryoji Hayashi. (2018) Organic Anion–Transporting Polypeptide (OATP)–Mediated Drug-Drug Interaction Study between Rosuvastatin and Cyclosporine A in Chimeric Mice with Humanized Liver. Drug Metabolism and Disposition 46:1, pages 11-19.
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Edwin C. Y. Chow, Holly P. Quach, Yueping Zhang, Jason Z. Y. Wang, David C. Evans, Albert P. Li, Jose Silva, Rommel G. Tirona, Yurong Lai & K. Sandy Pang. (2017) Disrupted Murine Gut–to–Human Liver Signaling Alters Bile Acid Homeostasis in Humanized Mouse Liver Models. Journal of Pharmacology and Experimental Therapeutics 360:1, pages 174-191.
Crossref
Crossref
K. Samuelsson, N. Scheer, I. Wilson, C.R. Wolf & C.J. Henderson. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III
130
149
.
Kota Kato, Masato Ohbuchi, Satoko Hamamura, Hiroki Ohshita, Yasuhiro Kazuki, Mitsuo Oshimura, Koya Sato, Naoyuki Nakada, Akio Kawamura, Takashi Usui, Hidetaka Kamimura & Chise Tateno. (2015)
Development of Murine
Cyp3a
Knockout Chimeric Mice with Humanized Liver
. Drug Metabolism and Disposition 43:8, pages 1208-1217.
Crossref
Crossref
Chise Tateno, Toshinobu Yamamoto, Rie Utoh, Chihiro Yamasaki, Yuji Ishida, Yuka Myoken, Ken Oofusa, Miyoko Okada, Naohisa Tsutsui & Katsutoshi Yoshizato. (2014) Chimeric Mice with Hepatocyte-humanized Liver as an Appropriate Model to Study Human Peroxisome Proliferator–activated Receptor-α. Toxicologic Pathology 43:2, pages 233-248.
Crossref
Crossref
Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie & Tetsuya Terasaki. (2014) Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS. Drug Metabolism and Disposition 42:6, pages 1039-1043.
Crossref
Crossref
Thomas J. Bateman, Vijay G.B. Reddy, Masakazu Kakuni, Yoshio Morikawa & Sanjeev Kumar. (2014) Application of Chimeric Mice with Humanized Liver for Study of Human-Specific Drug Metabolism. Drug Metabolism and Disposition 42:6, pages 1055-1065.
Crossref
Crossref
Seigo Sanoh & Shigeru Ohta. (2013) Chimeric mice transplanted with human hepatocytes as a model for prediction of human drug metabolism and pharmacokinetics. Biopharmaceutics & Drug Disposition 35:2, pages 71-86.
Crossref
Crossref
Asato Tachibana, Chise Tateno & Katsutoshi Yoshizato. (2013) Repopulation of the immunosuppressed retrorsine‐treated infant rat liver with human hepatocytes. Xenotransplantation 20:4, pages 227-238.
Crossref
Crossref
Yurong Lai. 2013. Transporters in Drug Discovery and Development. Transporters in Drug Discovery and Development
675
718
.
Chise Tateno, Fuyuki Miya, Kenjiro Wake, Miho Kataoka, Yuji Ishida, Chihiro Yamasaki, Ami Yanagi, Masakazu Kakuni, Eddie Wisse, Fons Verheyen, Kouji Inoue, Kota Sato, Atsushi Kudo, Shigeki Arii, Toshiyuki Itamoto, Toshimasa Asahara, Tatsuhiko Tsunoda & Katsutoshi Yoshizato. (2013) Morphological and microarray analyses of human hepatocytes from xenogeneic host livers. Laboratory Investigation 93:1, pages 54-71.
Crossref
Crossref
Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Naoto Uramaru, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura & Shigeru Ohta. (2012) Predictability of Metabolism of Ibuprofen and Naproxen Using Chimeric Mice with Human Hepatocytes. Drug Metabolism and Disposition 40:12, pages 2267-2272.
Crossref
Crossref
Alexander V. LyubimovAndrew Bessire, Kuresh Youdim, Susan Hurst & Caroline A. Lee. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
88
.
Alexander V. LyubimovJasminder Sahi, Yurong Lai & Caroline Lee. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
51
.
Masakazu Kakuni, Mayu Morita, Kentaro Matsuo, Yumiko Katoh, Miki Nakajima, Chise Tateno & Tsuyoshi Yokoi. (2012) Chimeric mice with a humanized liver as an animal model of troglitazone-induced liver injury. Toxicology Letters 214:1, pages 9-18.
Crossref
Crossref
Seigo Sanoh, Aya Horiguchi, Kazumi Sugihara, Yaichiro Kotake, Yoshitaka Tayama, Hiroki Ohshita, Chise Tateno, Toru Horie, Shigeyuki Kitamura & Shigeru Ohta. (2012) Prediction of In Vivo Hepatic Clearance and Half-Life of Drug Candidates in Human Using Chimeric Mice with Humanized Liver. Drug Metabolism and Disposition 40:2, pages 322-328.
Crossref
Crossref
Chise Tateno, Miho Kataoka, Rie Utoh, Asato Tachibana, Toshiyuki Itamoto, Toshimasa Asahara, Fuyuki Miya, Tatsuhiko Tsunoda & Katsutoshi Yoshizato. (2011) Growth Hormone-Dependent Pathogenesis of Human Hepatic Steatosis in a Novel Mouse Model Bearing a Human Hepatocyte-Repopulated Liver. Endocrinology 152:4, pages 1479-1491.
Crossref
Crossref
Masuhiro Nishimura, Yoko Ejiri, Sanae Kishimoto, Satoshi Suzuki, Tetsuo Satoh, Toru Horie, Shizuo Narimatsu & Shinsaku Naito. (2011) Expression Levels of Drug-Metabolizing Enzyme, Transporter, and Nuclear Receptor mRNAs in a Novel Three-Dimensional Culture System for Human Hepatocytes Using Micro-space Plates. Drug Metabolism and Pharmacokinetics 26:2, pages 137-144.
Crossref
Crossref
Chie Emoto, Kazuhide IwasakiNorie Murayama & Hiroshi Yamazaki. (2011) Drug Metabolism and Toxicity in Chimeric Mice with Humanized Liver. Journal of Health Science 57:1, pages 22-27.
Crossref
Crossref
Ryota Kikuchi, Matthew McCown, Pamela Olson, Chise Tateno, Yoshio Morikawa, Yumiko Katoh, David L. Bourdet, Mario Monshouwer & Adrian J. Fretland. (2010) Effect of Hepatitis C Virus Infection on the mRNA Expression of Drug Transporters and Cytochrome P450 Enzymes in Chimeric Mice with Humanized Liver. Drug Metabolism and Disposition 38:11, pages 1954-1961.
Crossref
Crossref
Glenn H. Cantor. 2010. Predictive Toxicology in Drug Safety. Predictive Toxicology in Drug Safety
269
283
.
Masuhiro Nishimura, Mieko Hagi, Yoko Ejiri, Sanae Kishimoto, Toru Horie, Shizuo Narimatsu & Shinsaku Naito. (2010) Secretion of Albumin and Induction of CYP1A2 and CYP3A4 in Novel Three-dimensional Culture System for Human Hepatocytes using Micro-space Plate. Drug Metabolism and Pharmacokinetics 25:3, pages 236-242.
Crossref
Crossref
Hidetaka Kamimura, Naoyuki Nakada, Katsuhiro Suzuki, Ayako Mera, Kinya Souda, Yuichi Murakami, Kohichiro Tanaka, Takafumi Iwatsubo, Akio Kawamura & Takashi Usui. (2010) Assessment of Chimeric Mice with Humanized Liver as a Tool for Predicting Circulating Human Metabolites. Drug Metabolism and Pharmacokinetics 25:3, pages 223-235.
Crossref
Crossref
Stephen C. Strom, Julio Davila & Markus Grompe. 2010. Hepatocytes. Hepatocytes
491
509
.
Katsutoshi Yoshizato & Chise Tateno. (2009) A Human Hepatocyte-Bearing Mouse: An Animal Model to Predict Drug Metabolism and Effectiveness in Humans. PPAR Research 2009, pages 1-11.
Crossref
Crossref
Olavi Pelkonen, Miia Turpeinen, Jukka Hakkola, Paavo Honkakoski, Janne Hukkanen & Hannu Raunio. (2008) Inhibition and induction of human cytochrome P450 enzymes: current status. Archives of Toxicology 82:10, pages 667-715.
Crossref
Crossref
Yuka Igarashi, Chise Tateno, Yuka Tanaka, Asato Tachibana, Rie Utoh, Miho Kataoka, Hideki Ohdan, Toshimasa Asahara & Katsutoshi Yoshizato. (2008) Engraftment of human hepatocytes in the livers of rats bearing bone marrow reconstructed with immunodeficient mouse bone marrow cells. Xenotransplantation 15:4, pages 235-245.
Crossref
Crossref
Yasushi Sato, Hiroshi Yamada, Kazuhide Iwasaki, Chise Tateno, Tsuyoshi Yokoi, Katsutoshi Yoshizato & Ikuo Horii. (2008) Human Hepatocytes Can Repopulate Mouse Liver: Histopathology of the Liver in Human Hepatocyte-Transplanted Chimeric Mice and Toxicologic Responses to Acetaminophen. Toxicologic Pathology 36:4, pages 581-591.
Crossref
Crossref
Miki Katoh, Chise Tateno, Katsutoshi Yoshizato & Tsuyoshi Yokoi. (2008) Chimeric mice with humanized liver. Toxicology 246:1, pages 9-17.
Crossref
Crossref
Hisaya Azuma, Nicole Paulk, Aarati Ranade, Craig Dorrell, Muhsen Al-Dhalimy, Ewa Ellis, Stephen Strom, Mark A Kay, Milton Finegold & Markus Grompe. (2007) Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice. Nature Biotechnology 25:8, pages 903-910.
Crossref
Crossref
Eric C.K. SiuRachel F. Tyndale. (2007) Non-Nicotinic Therapies for Smoking Cessation. Annual Review of Pharmacology and Toxicology 47:1, pages 541-564.
Crossref
Crossref
Masuhiro Nishimura & Shinsaku Naito. (2007) Tissue-Specific mRNA Expression Profiles of Human Carbohydrate Sulfotransferase and Tyrosylprotein Sulfotransferase. Biological & Pharmaceutical Bulletin 30:4, pages 821-825.
Crossref
Crossref
Hiroki Yoshitsugu, Masuhiro Nishimura, Chise Tateno, Miho Kataoka, Eiji Takahashi, Yoshinori Soeno, Katsutoshi Yoshizato, Tsuyoshi Yokoi & Shinsaku Naito. (2006) Evaluation of Human CYP1A2 and CYP3A4 mRNA Expression in Hepatocytes from Chimeric Mice with Humanized Liver. Drug Metabolism and Pharmacokinetics 21:6, pages 465-474.
Crossref
Crossref
Masuhiro Nishimura & Shinsaku Naito. (2006) Tissue-Specific mRNA Expression Profiles of Human Phase I Metabolizing Enzymes Except for Cytochrome P450 and Phase II Metabolizing Enzymes. Drug Metabolism and Pharmacokinetics 21:5, pages 357-374.
Crossref
Crossref