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Xenobiotica
the fate of foreign compounds in biological systems
Volume 36, 2006 - Issue 5
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Research Article

Stereoselectivity in metabolism of ifosfamide by CYP3A4 and CYP2B6

H. Lu Colleges of Pharmacy and Medicine and Comprehensive Cancer Center, Ohio State University, Columbus, OH, USA
,
J. J. Wang Colleges of Pharmacy and Medicine and Comprehensive Cancer Center, Ohio State University, Columbus, OH, USA
,
K. K. Chan Colleges of Pharmacy and Medicine and Comprehensive Cancer Center, Ohio State University, Columbus, OH, USA
&
P. A. Philip Division of Hematology and Oncology, Wayne State University, Detroit, MI, USA
Pages 367-385 | Received 24 Oct 2005, Published online: 22 Sep 2008

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Jing Gu, Zheng Sui, Chunshu Fang & Qunyou Tan. (2017) Stereochemical considerations in pharmacokinetic processes of representative antineoplastic agents. Drug Metabolism Reviews 49:4, pages 438-450.
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Mohamad Bassam Sonbol, Vishal Rana, S. Sirop Kenderian, Heidi Finnes & Thomas E. Witzig. (2014) Therapeutic options for patients with lymphoma and liver dysfunction or failure during mechlorethamine shortage. Leukemia & Lymphoma 55:8, pages 1815-1821.
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Hong Lu. (2007) Stereoselectivity in drug metabolism. Expert Opinion on Drug Metabolism & Toxicology 3:2, pages 149-158.
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Articles from other publishers (12)

Slobodan P. Rendic & F. Peter Guengerich. (2024) Formation of potentially toxic metabolites of drugs in reactions catalyzed by human drug-metabolizing enzymes. Archives of Toxicology.
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Lawrence H. Lash. 2024. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Ethan D. Angle & Philip M. Cox. (2023) Multidisciplinary Insights into the Structure–Function Relationship of the CYP2B6 Active Site. Drug Metabolism and Disposition 51:3, pages 369-384.
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Chenyang Ji, Philip Tanabe, Qingyang Shi, Le Qian, Victoria McGruer, Jason T. Magnuson, Xinru Wang, Jay Gan, Rama S. Gadepalli, John Rimoldi & Daniel Schlenk. (2021) Stage Dependent Enantioselective Metabolism of Bifenthrin in Embryos of Zebrafish ( Danio rerio ) and Japanese Medaka ( Oryzias latipes ) . Environmental Science & Technology 55:13, pages 9087-9096.
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Slobodan P. Rendic & F. Peter Guengerich. (2021) Human Family 1–4 cytochrome P450 enzymes involved in the metabolic activation of xenobiotic and physiological chemicals: an update. Archives of Toxicology 95:2, pages 395-472.
Crossref
Evan D. Kharasch & Amanda Crafford. (2018) Common Polymorphisms of CYP2B6 Influence Stereoselective Bupropion Disposition . Clinical Pharmacology & Therapeutics 105:1, pages 142-152.
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L.H. Lash. 2018. Comprehensive Toxicology. Comprehensive Toxicology 380 409 .
Li Di & Edward H. Kerns. 2016. Drug-Like Properties. Drug-Like Properties 161 194 .
Slobodan Rendic & F. Peter Guengerich. (2012) Contributions of Human Enzymes in Carcinogen Metabolism. Chemical Research in Toxicology 25:7, pages 1316-1383.
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V.B. Urlacher. 2012. Comprehensive Chirality. Comprehensive Chirality 275 294 .
Hanqing Dong, Xiaochuan Guo & Zengbiao Li. 2011. Chiral Drugs. Chiral Drugs 347 379 .
Edward H. Kerns & Li Di. 2008. Drug-like Properties: Concepts, Structure Design and Methods. Drug-like Properties: Concepts, Structure Design and Methods 137 II .

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