Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 36, 2006 - Issue 7
Submit an article Journal homepage
218
Views
19
CrossRef citations to date
0
Altmetric
Research Article

Role for enhanced faecal excretion of bile acid in hydroxysteroid sulfotransferase-mediated protection against lithocholic acid-induced liver toxicity

M. Miyata Division of Drug Metabolism and Molecular Toxicology, Tohoku University, Graduate School of Pharmaceutical Sciences, Sendai, Japan
,
H. Watase Division of Drug Metabolism and Molecular Toxicology, Tohoku University, Graduate School of Pharmaceutical Sciences, Sendai, Japan
,
W. Hori Division of Drug Metabolism and Molecular Toxicology, Tohoku University, Graduate School of Pharmaceutical Sciences, Sendai, Japan
,
M. Shimada Division of Drug Metabolism and Molecular Toxicology, Tohoku University, Graduate School of Pharmaceutical Sciences, Sendai, Japan
,
K. Nagata Division of Drug Metabolism and Molecular Toxicology, Tohoku University, Graduate School of Pharmaceutical Sciences, Sendai, Japan
,
F. J. Gonzalez Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
&
Y. Yamazoe Division of Drug Metabolism and Molecular Toxicology, Tohoku University, Graduate School of Pharmaceutical Sciences, Sendai, Japan; Tohoku University 21st Century, COE Program “Comprehensive Research and Education Center for Planning of Drug Development and Clinical Evaluation”, Sendai, Japan
 show all
Pages 631-644 | Received 09 Feb 2006, Accepted 27 Apr 2006, Published online: 22 Sep 2008

Citations (19)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Melissa Runge-Morris, Thomas A. Kocarek & Charles N. Falany. (2013) Regulation of the cytosolic sulfotransferases by nuclear receptors. Drug Metabolism Reviews 45:1, pages 15-33.
Read now

Articles from other publishers (18)

Qian Wang, Guo-Chao Song, Feng-Yi Weng, Bin Zou, Jing-Yi Jin, Dong-Ming Yan, Bo Tan, Jing Zhao, Yue Li & Fu-Rong Qiu. (2022) Hepatoprotective Effects of Glycyrrhetinic Acid on Lithocholic Acid-Induced Cholestatic Liver Injury Through Choleretic and Anti-Inflammatory Mechanisms. Frontiers in Pharmacology 13.
Crossref
Benjamin H Mullish, Daryn R Michael, Julie AK McDonald, Giulia Masetti, Sue F Plummer & Julian R Marchesi. (2021) Identifying the factors influencing outcome in probiotic studies in overweight and obese patients: host or microbiome?. Gut 70:1, pages 225-226.
Crossref
Masaaki Miyata, Kenjiro Hayashi, Hiroki Yamakawa, Yasushi Yamazoe & Kouichi Yoshinari. (2015) Antibacterial Drug Treatment Increases Intestinal Bile Acid Absorption <i>via</i> Elevated Levels of Ileal Apical Sodium-Dependent Bile Acid Transporter but Not Organic Solute Transporter α Protein. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 38:3, pages 493-496.
Crossref
Kathleen G. Barrett, Hailin Fang, Mary D. Gargano, Daniel Markovich, Thomas A. Kocarek & Melissa Runge-Morris. (2013) Regulation of Murine Hepatic Hydroxysteroid Sulfotransferase Expression in Hyposulfatemic Mice and in a Cell Model of 3′-Phosphoadenosine-5′-Phosphosulfate Deficiency. Drug Metabolism and Disposition 41:8, pages 1505-1513.
Crossref
Masaaki Miyata, Hiroki Yamakawa, Kenjiro Hayashi, Hideaki Kuribayashi, Yasushi Yamazoe & Kouichi Yoshinari. (2013) Ileal apical sodium-dependent bile acid transporter protein levels are down-regulated through ubiquitin-dependent protein degradation induced by bile acids. European Journal of Pharmacology 714:1-3, pages 507-514.
Crossref
Tsutomu Matsubara, Naoki Tanaka, Misako Sato, Dong Wook Kang, Kristopher W. Krausz, Kathleen C. Flanders, Kazuo Ikeda, Hans Luecke, Lalage M. Wakefield & Frank J. Gonzalez. (2012) TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury. Journal of Lipid Research 53:12, pages 2698-2707.
Crossref
Hideaki Kuribayashi, Masaaki Miyata, Hiroki Yamakawa, Kouichi Yoshinari & Yasushi Yamazoe. (2012) Enterobacteria-mediated deconjugation of taurocholic acid enhances ileal farnesoid X receptor signaling. European Journal of Pharmacology 697:1-3, pages 132-138.
Crossref
Anne Laure Sberna, Mahfoud Assem, Thomas Gautier, Jacques Grober, Boris Guiu, Aline Jeannin, Jean-Paul Pais de Barros, Anne Athias, Laurent Lagrost & David Masson. (2011) Constitutive androstane receptor activation stimulates faecal bile acid excretion and reverse cholesterol transport in mice. Journal of Hepatology 55:1, pages 154-161.
Crossref
Tsutomu Matsubara, Naoki Tanaka, Andrew D. Patterson, Joo-Youn Cho, Kristopher W. Krausz & Frank J. Gonzalez. (2011) Lithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis in mice. Hepatology 53:4, pages 1282-1293.
Crossref
Masaaki Miyata, Yumi Sakaida, Hitomi Matsuzawa, Kouichi Yoshinari & Yasushi Yamazoe. (2011) Fibroblast Growth Factor 19 Treatment Ameliorates Disruption of Hepatic Lipid Metabolism in Farnesoid X Receptor (Fxr)-Null Mice. Biological and Pharmaceutical Bulletin 34:12, pages 1885-1889.
Crossref
Masaaki Miyata, Hiroki Yamakawa, Mayumi Hamatsu, Hideaki Kuribayashi, Yuki Takamatsu & Yasushi Yamazoe. (2011) Enterobacteria Modulate Intestinal Bile Acid Transport and Homeostasis through Apical Sodium-Dependent Bile Acid Transporter (SLC10A2) Expression. Journal of Pharmacology and Experimental Therapeutics 336:1, pages 188-196.
Crossref
Masaaki Miyata, Masahiro Nomoto, Fumiaki Sotodate, Tomohiro Mizuki, Wataru Hori, Miho Nagayasu, Shinya Yokokawa, Shin-ichi Ninomiya & Yasushi Yamazoe. (2010) Possible protective role of pregnenolone-16α-carbonitrile in lithocholic acid-induced hepatotoxicity through enhanced hepatic lipogenesis. European Journal of Pharmacology 636:1-3, pages 145-154.
Crossref
Masaaki Miyata, Yuki Takamatsu, Hideaki Kuribayashi & Yasushi Yamazoe. (2009) Administration of Ampicillin Elevates Hepatic Primary Bile Acid Synthesis through Suppression of Ileal Fibroblast Growth Factor 15 Expression. Journal of Pharmacology and Experimental Therapeutics 331:3, pages 1079-1085.
Crossref
Yazen Alnouti. (2009) Bile Acid Sulfation: A Pathway of Bile Acid Elimination and Detoxification. Toxicological Sciences 108:2, pages 225-246.
Crossref
Masaaki Miyata, Yoshiki Matsuda, Masahiro Nomoto, Yuki Takamatsu, Nozomi Sato, Mayumi Hamatsu, Paul A. Dawson, Frank J. Gonzalez & Yasushi Yamazoe. (2009) Cholesterol Feeding Prevents Hepatic Accumulation of Bile Acids in Cholic Acid-Fed Farnesoid X Receptor (FXR)-Null Mice: FXR-Independent Suppression of Intestinal Bile Acid Absorption. Drug Metabolism and Disposition 37:2, pages 338-344.
Crossref
Tsutomu Matsubara, Kouichi Yoshinari, Kazunobu Aoyama, Mika Sugawara, Yuji Sekiya, Kiyoshi Nagata & Yasushi Yamazoe. (2008) Role of Vitamin D Receptor in the Lithocholic Acid-Mediated CYP3A Induction in Vitro and in Vivo. Drug Metabolism and Disposition 36:10, pages 2058-2063.
Crossref
Genta Kakiyama, Hideyuki Tamegai, Takashi Iida, Kuniko Mitamura, Shigeo Ikegawa, Takaaki Goto, Nariyasu Mano, Junichi Goto, Peter Holz, Lee R. Hagey & Alan F. Hofmann. (2007) Isolation and chemical synthesis of a major, novel biliary bile acid in the common wombat (Vombatus ursinus): 15α-hydroxylithocholic acid. Journal of Lipid Research 48:12, pages 2682-2692.
Crossref
Masahiro Nomoto, Masaaki Miyata, Miki Shimada, Kouichi Yoshinari, Frank J Gonzalez, Shigeki Shibasaki, Tohru Kurosawa, Yasuhiro Shindo & Yasushi Yamazoe. (2007) ME3738 protects against lithocholic acid-induced hepatotoxicity, which is associated with enhancement of biliary bile acid and cholesterol output. European Journal of Pharmacology 574:2-3, pages 192-200.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.