Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 36, 2006 - Issue 12
245
Views
34
CrossRef citations to date
0
Altmetric
Original

Inter-individual variation of cytochrome P4502J2 expression and catalytic activities in liver microsomes from Japanese and Caucasian populations

, , , &
Pages 1201-1209 | Received 30 May 2006, Accepted 05 Aug 2006, Published online: 11 Aug 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Robert Valencia, Wesam Bassiouni, Ahmed M. Darwesh, Raj Bapuji & John M. Seubert. (2022) Cardiomyocyte-specific CYP2J2 and its therapeutic implications. Expert Opinion on Drug Metabolism & Toxicology 18:7-8, pages 423-439.
Read now
Ayaka Kojima, Masayuki Nadai, Norie Murayama, Hiroshi Yamazaki & Miki Katoh. (2022) Effects of multi-kinase inhibitors on the activity of cytochrome P450 2J2. Xenobiotica 52:7, pages 669-675.
Read now
Ayaka Kojima, Ayuka Sogabe, Masayuki Nadai & Miki Katoh. (2021) Species differences in oxidative metabolism of regorafenib. Xenobiotica 51:12, pages 1400-1407.
Read now
Michael Murray. (2016) CYP2J2 – regulation, function and polymorphism. Drug Metabolism Reviews 48:3, pages 351-368.
Read now
Shotaro Uehara, Norie Murayama, Yasuharu Nakanishi, Chika Nakamura, Takanori Hashizume, Darryl C. Zeldin, Hiroshi Yamazaki & Yasuhiro Uno. (2015) Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine. Xenobiotica 45:2, pages 124-130.
Read now
Wei Zhang, Mary W Roederer, Wang-Qing Chen, Lan Fan & Hong-Hao Zhou. (2012) Pharmacogenetics of Drugs Withdrawn from the Market. Pharmacogenomics 13:2, pages 223-231.
Read now
Rüdiger Kaspera & Rheem A Totah. (2009) Epoxyeicosatrienoic acids: formation, metabolism and potential role in tissue physiology and pathophysiology. Expert Opinion on Drug Metabolism & Toxicology 5:7, pages 757-771.
Read now
Katherine N Theken & Craig R Lee. (2007) Genetic Variation in the Cytochrome P450 Epoxygenase Pathway and Cardiovascular Disease Risk. Pharmacogenomics 8:10, pages 1369-1383.
Read now
N. Murayama, M. Minoshima, M. Shimizu, F. P. Guengerich & H. Yamazaki. (2007) Involvement of human cytochrome P450 2B6 in the - and 4-hydroxylation of the anesthetic agent propofol. Xenobiotica 37:7, pages 717-724.
Read now

Articles from other publishers (25)

Jacqueline Wen Hui Leow & Eric Chun Yong Chan. (2024) CYP2J2-mediated metabolism of arachidonic acid in heart: A review of its kinetics, inhibition and role in heart rhythm control. Pharmacology & Therapeutics 258, pages 108637.
Crossref
Li-Li Zou, Fang-Ling Zhao, Yu-Ying Qi, Shuang-Hu Wang, Quan Zhou, Pei-Wu Geng, Yun-Fang Zhou, Qing Zhang, Hao Chen, Da-Peng Dai, Jian-Ping Cai & Fu-Sui Ji. (2023) Characterization of 15 CYP2J2 variants identified in the Chinese Han population on the metabolism of ebastine and terfenadine in vitro. Frontiers in Pharmacology 14.
Crossref
Livija Šimičević, Ana Marija Slišković, Majda Vrkić Kirhmajer, Lana Ganoci, Hrvoje Holik, Jozefina Palić, Jure Samardžić & Tamara Božina. (2023) Risk Factors for Rivaroxaban-Related Bleeding Events—Possible Role of Pharmacogenetics: Case Series. Pharmacy 11:1, pages 29.
Crossref
R. Scott Obach. (2022) Linezolid Metabolism Is Catalyzed by Cytochrome P450 2J2, 4F2, and 1B1. Drug Metabolism and Disposition 50:4, pages 413-421.
Crossref
Jacqueline Wen Hui Leow, Ravi Kumar Verma, Amos Boon Hao Lim, Hao Fan & Eric Chun Yong Chan. (2021) Atypical kinetics of cytochrome P450 2J2: Epoxidation of arachidonic acid and reversible inhibition by xenobiotic inhibitors. European Journal of Pharmaceutical Sciences 164, pages 105889.
Crossref
Xiao-Xiao An, Yichao Yu, Guo-Fu Li & Guo Yu. (2020) Abundance and Associated Variations of Cytochrome P450 Drug-Metabolizing Enzymes in the Liver of East Asian Adults: A Meta-Analysis. European Journal of Drug Metabolism and Pharmacokinetics 46:2, pages 225-233.
Crossref
Yanpeng Dai, Tianzi Xue, Hefang Ji, Pan Zhang, Dongdong Zhang & Zhengjian Qi. (2021) In situ target enzyme-activated near-infrared fluorescent probe: A case study of CYP2J2 using three-fragmentary molecular assembly engineering. Sensors and Actuators B: Chemical 328, pages 129034.
Crossref
Marco Sisignano, Dieter Steinhilber, Michael J. Parnham & Gerd Geisslinger. (2020) Exploring CYP2J2: lipid mediators, inhibitors and therapeutic implications. Drug Discovery Today 25:9, pages 1744-1753.
Crossref
Yong Chen, Yun Jiang, Jingjing Qu, Qiming Wang, Yuxian Bai, Jianhua Shi, Yehui Shi, Xue Chen, Nong Yang, Jianfu Heng & Kunyan Li. (2020) Pharmacokinetic and bioequivalence study of new S-1 capsule in Chinese cancer patients. European Journal of Pharmaceutical Sciences 151, pages 105384.
Crossref
Valérie Clermont, Alexia Grangeon, Azemi Barama, Jacques Turgeon, Michel Lallier, Jacques Malaise & Veronique Michaud. (2019) Activity and mRNA expression levels of selected cytochromes P450 in various sections of the human small intestine. British Journal of Clinical Pharmacology 85:6, pages 1367-1377.
Crossref
Jing Ning, Tao Liu, Peipei Dong, Wei Wang, Guangbo Ge, Bo Wang, Zhenlong Yu, Lei Shi, Xiangge Tian, Xiaokui Huo, Lei Feng, Chao Wang, Chengpeng Sun, Jingnan Cui, Tony D. James & Xiaochi Ma. (2018) Molecular Design Strategy to Construct the Near-Infrared Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2J2. Journal of the American Chemical Society 141:2, pages 1126-1134.
Crossref
Theresa Aliwarga, Eric Evangelista, Nona Sotoodehnia, Rozenn Lemaitre & Rheem Totah. (2018) Regulation of CYP2J2 and EET Levels in Cardiac Disease and Diabetes. International Journal of Molecular Sciences 19:7, pages 1916.
Crossref
F. Peter Guengerich. 2015. Cytochrome P450. Cytochrome P450 523 785 .
Ahmad Al Ali, David Touboul, Jean-Pierre Le Caër, Isabelle Schmitz-Afonso, Jean-Pierre Flinois, Catherine Marchetti, Isabelle De Waziers, Alain Brunelle, Olivier Laprévote & Philippe Beaune. (2014) Optimization and validation of a label-free MRM method for the quantification of cytochrome P450 isoforms in biological samples. Analytical and Bioanalytical Chemistry 406:20, pages 4861-4874.
Crossref
Zhexue Wu, Doohyun Lee, Jeongmin Joo, Jung-Hoon Shin, Wonku Kang, Sangtaek Oh, Do Yup Lee, Su-Jun Lee, Sung Su Yea, Hye Suk Lee, Taeho Lee & Kwang-Hyeon Liu. (2013) CYP2J2 and CYP2C19 Are the Major Enzymes Responsible for Metabolism of Albendazole and Fenbendazole in Human Liver Microsomes and Recombinant P450 Assay Systems. Antimicrobial Agents and Chemotherapy 57:11, pages 5448-5456.
Crossref
Ulrich M. Zanger & Matthias Schwab. (2013) Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation. Pharmacology & Therapeutics 138:1, pages 103-141.
Crossref
Maho Okubo, Norie Murayama, Makiko Shimizu, Tsutomu Shimada, F. Peter Guengerich & Hiroshi Yamazaki. (2013) The <i>CYP3A4</i> intron 6 C>T polymorphism (<i>CYP3A4*22</i>) is associated with reduced CYP3A4 protein level and function in human liver microsomes. The Journal of Toxicological Sciences 38:3, pages 349-354.
Crossref
Caroline A. Lee, J. P. JonesIIIIII, Jonathan Katayama, Rüdiger Kaspera, Ying Jiang, Sascha Freiwald, Evan Smith, Gregory S. Walker & Rheem A. Totah. (2012) Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity. Drug Metabolism and Disposition 40:5, pages 943-951.
Crossref
Goutam Chowdhury, Norie Murayama, Yusuke Okada, Yasuhiro Uno, Makiko Shimizu, Norio Shibata, F. Peter Guengerich & Hiroshi Yamazaki. (2010) Human Liver Microsomal Cytochrome P450 3A Enzymes Involved in Thalidomide 5-Hydroxylation and Formation of a Glutathione Conjugate. Chemical Research in Toxicology 23:6, pages 1018-1024.
Crossref
Pei H Cui, Andy C Lee, Fanfan Zhou & Michael Murray. (2010) Impaired transactivation of the human CYP2J2 arachidonic acid epoxygenase gene in HepG2 cells subjected to nitrative stress. British Journal of Pharmacology 159:7, pages 1440-1449.
Crossref
Satomi Nagashima, Makiko Shimizu, Hiroshi Yano, Norie Murayama, Toshio Kumai, Shinichi Kobayashi, F. Peter Guengerich & Hiroshi Yamazaki. (2009) Inter-individual Variation in Flavin-containing Monooxygenase 3 in Livers from Japanese: Correlation with Hepatic Transcription Factors. Drug Metabolism and Pharmacokinetics 24:3, pages 218-225.
Crossref
Yusuke Okada, Norie Murayama, Chihiro Yanagida, Makiko Shimizu, F. Peter Guengerich & Hiroshi Yamazaki. (2009) Drug Interactions of Thalidomide with Midazolam and Cyclosporine A: Heterotropic Cooperativity of Human Cytochrome P450 3A5. Drug Metabolism and Disposition 37:1, pages 18-23.
Crossref
Haruo Takeshita, Etsuko Tsubota, Hisakazu Takatsuka, Takashi Kunito & Junko Fujihara. (2008) Cytochrome P450 2J2*7 polymorphisms in Japanese, Mongolians and Ovambos . Cell Biochemistry and Function 26:7, pages 813-816.
Crossref
Kaeko Nakayama, Takeaki Nitto, Teruo Inoue & Koichi Node. (2008) Expression of the cytochrome P450 epoxygenase CYP2J2 in human monocytic leukocytes. Life Sciences 83:9-10, pages 339-345.
Crossref
Norie Murayama, Naoko Imai, Takahisa Nakane, Makiko Shimizu & Hiroshi Yamazaki. (2007) Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes. Biochemical Pharmacology 73:12, pages 2020-2026.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.