Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 37, 2007 - Issue 3
Submit an article Journal homepage
89
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Distribution of radioactivity and metabolite profiling in tumour and plasma following intravenous administration of a colchicine derivative (14C-ZD6126) to tumour-bearing mice

R. A. D'Souza AstraZeneca, Alderley Park, Macclesfield, UK
,
E. A. Partridge AstraZeneca, Alderley Park, Macclesfield, UK
,
D. W. Roberts AstraZeneca, Alderley Park, Macclesfield, UK
,
S. Ashton AstraZeneca, Alderley Park, Macclesfield, UK
,
A. Ryan AstraZeneca, Alderley Park, Macclesfield, UK
,
A. B. Patterson Charles River Laboratories, Tranent, UK
,
Z. Wilson AstraZeneca, Alderley Park, Macclesfield, UK
&
C. C. Thurrell AstraZeneca, Alderley Park, Macclesfield, UK
 show all
Pages 328-340 | Received 21 Nov 2006, Accepted 13 Dec 2006, Published online: 22 Sep 2008

Citations (10)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

E. A. Partridge, R. A. D'souza, E. M. Lenz, S. M. Smith, J. Clarkson-Jones & D. W. Roberts. (2008) Disposition and metabolism of the colchicine derivative [14C]-ZD6126 in rat and dog. Xenobiotica 38:4, pages 399-421.
Read now

Articles from other publishers (9)

Krishna Kanta Ghosh, Parasuraman Padmanabhan, Chang-Tong Yang, Sachin Mishra, Christer Halldin & Balázs Gulyás. (2020) Dealing with PET radiometabolites. EJNMMI Research 10:1.
Crossref
Mohammad Mahdi Moein, Miklós Tóth, Lenke Tari, Andrea Varrone, Mohamed Abdel-Rehim & Christer Halldin. (2020) New approach in radiometabolite analysis of positron emission tomography (PET) radioligands; lead-shielded microextraction by packed sorbent as a tool for in vivo radiometabolite analysis of [11C]SMW139 in rat plasma. Talanta 208, pages 120449.
Crossref
Mohammad Mahdi Moein, Ryuji Nakao, Nahid Amini, Mohamed Abdel-Rehim, Magnus Schou & Christer Halldin. (2019) Sample preparation techniques for radiometabolite analysis of positron emission tomography radioligands; trends, progress, limitations and future prospects. TrAC Trends in Analytical Chemistry 110, pages 1-7.
Crossref
Natalia Penner, Lin Xu & Chandra Prakash. (2012) Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies in Drug Development: Why, When, and How?. Chemical Research in Toxicology 25:3, pages 513-531.
Crossref
Qingyu Zhou & James M. Gallo. 2011. Applications of Microdialysis in Pharmaceutical Science. Applications of Microdialysis in Pharmaceutical Science 403 430 .
Tammy L. KalberNazila KamalyStephanie A. HighamJohn A. PughJosephine BunchCameron W. McLeodAndrew D. MillerJimmy D. Bell. (2011) Synthesis and Characterization of a Theranostic Vascular Disrupting Agent for In Vivo MR Imaging . Bioconjugate Chemistry 22:5, pages 879-886.
Crossref
Mark Hayward, Maria D. Bacolod, Qing Ping Han, Manuel Cajina & Zack Zou. 2011. Mass Spectrometry in Drug Metabolism and Disposition. Mass Spectrometry in Drug Metabolism and Disposition 353 381 .
Rodney T. Brown, Victor L. Murrell, Austin McMordie, Madhavi Sriram, Kevin G. Pinney, Suman Sharma & David J. Chaplin. (2009) Carbon‐14 radiosynthesis of combretastatin A‐1 (CA1) and its corresponding phosphate prodrug (CA1P). Journal of Labelled Compounds and Radiopharmaceuticals 52:14, pages 567-570.
Crossref
Daniel P. Bradley, Jean J. Tessier, Susan E. Ashton, John C. Waterton, Zena Wilson, Philip L. Worthington & Anderson J. Ryan. (2007) Correlation of MRI Biomarkers with Tumor Necrosis in Hras5 Tumor Xenograft in Athymic Rats. Neoplasia 9:5, pages 382-391.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.