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Xenobiotica
the fate of foreign compounds in biological systems
Volume 37, 2007 - Issue 4
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Research Article

Comparison of cerebral pharmacokinetics of buprenorphine and norbuprenorphine in an in vivo sheep model

M. L. Jensen Department of Pharmacology and Pharmacotherapy, University of Copenhagen, Denmark
,
D. Foster School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia
,
R. Upton Discipline of Anaesthesia and Intensive Care, Royal Adelaide Hospital and University of Adelaide, Adelaide, Australia
,
C. Grant Discipline of Anaesthesia and Intensive Care, Royal Adelaide Hospital and University of Adelaide, Adelaide, Australia
,
A. Martinez Discipline of Anaesthesia and Intensive Care, Royal Adelaide Hospital and University of Adelaide, Adelaide, Australia
&
A. Somogyi Department of Clinical and Experimental Pharmacology, University of Adelaide, Australia
Pages 441-457 | Received 08 Jan 2007, Accepted 31 Jan 2007, Published online: 22 Sep 2008

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David E Moody. (2013) Metabolic and toxicological considerations of the opioid replacement therapy and analgesic drugs: methadone and buprenorphine. Expert Opinion on Drug Metabolism & Toxicology 9:6, pages 675-697.
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Articles from other publishers (19)

Leana J. Pande, Rhudjerry E. Arnet & Brian J. Piper. (2023) An Examination of the Complex Pharmacological Properties of the Non-Selective Opioid Modulator Buprenorphine. Pharmaceuticals 16:10, pages 1397.
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Henriikka Hakomäki, Sophia Eskola, Hannu Kokki, Marko Lehtonen, Juha Räsänen, Sakari Laaksonen, Hanna-Marja Voipio, Veli-Pekka Ranta & Merja Kokki. (2022) Central nervous system distribution of buprenorphine in pregnant sheep, fetuses and newborn lambs after continuous transdermal and single subcutaneous extended-release dosing. European Journal of Pharmaceutical Sciences 178, pages 106283.
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Lara A. Sypniewski, Heather Knych, Melanie Breshears, Wenfang B. Fang, David E. Moody, Pratyaydipta Rudra, Lara K. Maxwell, Jill K. Murray, Jerry Ritchey & João Brandão. (2022) Pharmacokinetics, blood and urine profile effects, and injection site histopathology following three daily injections of subcutaneous high concentration buprenorphine in New Zealand white rabbits (Oryctolagus cuniculus). Journal of Exotic Pet Medicine 43, pages 51-56.
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Arimi Fujita, Saki Noguchi, Rika Hamada, Satoko Inoue, Tsutomu Shimada, Satomi Katakura, Tetsuo Maruyama, Yoshimichi Sai, Tomohiro Nishimura & Masatoshi Tomi. (2022) Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers. Pharmaceutical Research 39:7, pages 1645-1658.
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Henriikka Hakomäki, Hannu Kokki, Marko Lehtonen, Veli‐Pekka Ranta, Juha Räsänen, Hanna‐Marja Voipio & Merja Kokki. (2021) Pharmacokinetics of buprenorphine in pregnant sheep after intravenous injection. Pharmacology Research & Perspectives 9:2.
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Lukas Kovar, Christina Schräpel, Dominik Selzer, Yvonne Kohl, Robert Bals, Matthias Schwab & Thorsten Lehr. (2020) Physiologically-Based Pharmacokinetic (PBPK) Modeling of Buprenorphine in Adults, Children and Preterm Neonates. Pharmaceutics 12:6, pages 578.
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Peter Athanasos, Walter Ling, Felix Bochner, Jason M White & Andrew A Somogyi. (2019) Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose. Pain Medicine 20:1, pages 119-128.
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Miranda J. Sadar, Heather K. Knych, Tracy L. Drazenovich & Joanne R. Paul-Murphy. (2018) Pharmacokinetics of buprenorphine after intravenous and oral transmucosal administration in guinea pigs (Cavia porcellus). American Journal of Veterinary Research 79:3, pages 260-266.
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Yi-Ya Wang, Xiao-Hang Shen, Hao Li, Feng-Ju Chen, Yan Fu & Li Ding. (2013) A sensitive, simple and rapid HPLC–MS/MS method for simultaneous quantification of buprenorpine and its N-dealkylated metabolite norbuprenorphine in human plasma. Journal of Pharmaceutical Analysis 3:4, pages 221-228.
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N. Lintzeris, S.Y. Leung, A.J. Dunlop, B. Larance, N. White, G.R. Rivas, R.M. Holland, L. Degenhardt, P. Muhleisen, M. Hurley & R. Ali. (2013) A randomised controlled trial of sublingual buprenorphine–naloxone film versus tablets in the management of opioid dependence. Drug and Alcohol Dependence 131:1-2, pages 119-126.
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Janet K. Coller, Jennifer R. Michalakas, Heather M. James, Aaron L. Farquharson, Joel Colvill, Jason M. White & Andrew A. Somogyi. (2012) Inhibition of CYP2D6‐mediated tramadol O‐demethylation in methadone but not buprenorphine maintenance patients. British Journal of Clinical Pharmacology 74:5, pages 835-841.
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Howard S. Smith. (2011) The Metabolism of Opioid Agents and the Clinical Impact of Their Active Metabolites. The Clinical Journal of Pain 27:9, pages 824-838.
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Kristen M Messenger, Jennifer L Davis, Douglas H LaFevers, Beth M Barlow & Lysa P Posner. (2011) Intravenous and sublingual buprenorphine in horses: pharmacokinetics and influence of sampling site. Veterinary Anaesthesia and Analgesia 38:4, pages 374-384.
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Jinda Fan, Sarah M. Brown, Zhude Tu & Evan D. Kharasch. (2011) Chemical and Enzyme-Assisted Syntheses of Norbuprenorphine-3-β- d -glucuronide . Bioconjugate Chemistry 22:4, pages 752-758.
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Trine Andresen, Richard N. Upton, David J.R. Foster, Lona L. Christrup, Lars Arendt‐Nielsen & Asbjørn M. Drewes. (2010) Pharmacokinetic/Pharmacodynamic Relationships of Transdermal Buprenorphine and Fentanyl in Experimental Human Pain Models. Basic & Clinical Pharmacology & Toxicology 108:4, pages 274-284.
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Ian G.V. James, Catherine M. O'Brien & Chris J. McDonald. (2010) A Randomized, Double-Blind, Double-Dummy Comparison of the Efficacy and Tolerability of Low-Dose Transdermal Buprenorphine (BuTrans Seven-Day Patches) With Buprenorphine Sublingual Tablets (Temgesic ) in Patients With Osteoarthritis Pain. Journal of Pain and Symptom Management 40:2, pages 266-278.
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Synnove Lindemalm, Per Nydert, Jan-Olov Svensson, Lars Stahle & Ihsan Sarman. (2009) Transfer of Buprenorphine Into Breast Milk and Calculation of Infant Drug Dose. Journal of Human Lactation 25:2, pages 199-205.
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Janet K. Coller, Lona L. Christrup & Andrew A. Somogyi. (2008) Role of active metabolites in the use of opioids. European Journal of Clinical Pharmacology 65:2, pages 121-139.
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Kannan Krishnan & Thomas Peyret. 2009. Ecotoxicology Modeling. Ecotoxicology Modeling 145 175 .

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