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Xenobiotica
the fate of foreign compounds in biological systems
Volume 37, 2007 - Issue 7
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Research Article

Involvement of human cytochrome P450 2B6 in the ω- and 4-hydroxylation of the anesthetic agent propofol

N. Murayama Showa Pharmaceutical University, Machida, Tokyo, Japan
,
M. Minoshima Showa Pharmaceutical University, Machida, Tokyo, Japan
,
M. Shimizu Showa Pharmaceutical University, Machida, Tokyo, Japan
,
F. P. Guengerich Vanderbilt University School of Medicine, NashvilleUSA
&
H. Yamazaki Showa Pharmaceutical University, Machida, Tokyo, Japan
Pages 717-724 | Received 07 Apr 2007, Accepted 14 May 2007, Published online: 22 Sep 2008

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Toru Oshio, Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2019) Marmoset cytochrome P450 2B6, a propofol hydroxylase expressed in liver. Xenobiotica 49:3, pages 265-269.
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Yasushi Yamazoe, Kazumi Ito & Kouichi Yoshinari. (2011) Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order. Drug Metabolism Reviews 43:4, pages 409-439.
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Articles from other publishers (10)

Guyi Wang, Bing Xiao, Jiayi Deng, Linmei Gong, Yi Li, Jinxiu Li & Yanjun Zhong. (2022) The Role of Cytochrome P450 Enzymes in COVID-19 Pathogenesis and Therapy. Frontiers in Pharmacology 13.
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Yvonne Gloor, Christoph Czarnetzki, François Curtin, Béatrice Gil-Wey, Martin R. Tramèr & Jules A. Desmeules. (2022) Genetic Susceptibility Toward Nausea and Vomiting in Surgical Patients. Frontiers in Genetics 12.
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Alexander V. LyubimovEugene G. Hrycay & Stelvio M. Bandiera. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 36 .
Yuki Kobayashi, Makito Yokozuka, Hidetoshi Miyakawa, Minoru Watanabe, Toshio Kumai & Takeshi Tateda. (2015) Effects of Genetic Polymorphism of CYP2B6 and UGT1A9 and Sex Differences on Pharmacokinetics of Propofol. Journal of St. Marianna University 6:2, pages 183-193.
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Andrew G. Leach & Nathan J. Kidley. 2014. Drug Metabolism Prediction. Drug Metabolism Prediction 103 132 .
Yoon Ji ChoiKoo KwonGo Eun BaeSeung Zhoo YoonHye Won LeeHae Ja Lim. (2014) An unexpected increase of entropy in a sleepwalking disorder patient during propofol and remifentanil anesthesia: a case report. Korean Journal of Anesthesiology 67:4, pages 270.
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Greyson P Twist, Roger Gaedigk, J Steven Leeder & Andrea Gaedigk. (2013) High-resolution melt analysis to detect sequence variations in highly homologous gene regions: application to CYP2B6 . Pharmacogenomics 14:8, pages 913-922.
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Markus R Meyer & Hans H Maurer. (2011) Absorption, distribution, metabolism and excretion pharmacogenomics of drugs of abuse. Pharmacogenomics 12:2, pages 215-233.
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Fumiyasu Kansaku, Toshio Kumai, Kuniharu Sasaki, Makito Yokozuka, Makiko Shimizu, Tadashi Tateda, Norie Murayama, Shinichi Kobayashi & Hiroshi Yamazaki. (2011) Individual Differences in Pharmacokinetics and Pharmacodynamics of Anesthetic Agent Propofol with Regard to CYP2B6 and UGT1A9 Genotype and Patient Age. Drug Metabolism and Pharmacokinetics 26:5, pages 532-537.
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Robert L. Walsky & R. Scott Obach. (2009) Measurement of In Vitro Cytochrome P450 2B6 Activity. Current Protocols in Toxicology 39:1.
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