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Xenobiotica
the fate of foreign compounds in biological systems
Volume 37, 2007 - Issue 9
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Research Article

In vitro metabolism of a triclyclic alkaloid (M445526) in human liver microsomes and hepatocytes

A. D. McCormick Drug Metabolism and Pharmacokinetics Department, AstraZeneca, Alderley Park, Macclesfield, UK
,
D. L. Slamon Drug Metabolism and Pharmacokinetics Department, AstraZeneca, Alderley Park, Macclesfield, UK
,
E. M. Lenz Drug Metabolism and Pharmacokinetics Department, AstraZeneca, Alderley Park, Macclesfield, UK
,
P. J. Phillips Drug Metabolism and Pharmacokinetics Department, AstraZeneca, Alderley Park, Macclesfield, UK
,
C. D. King Drug Metabolism and Pharmacokinetics Department, AstraZeneca, Alderley Park, Macclesfield, UK
,
D. Mckillop Drug Metabolism and Pharmacokinetics Department, AstraZeneca, Alderley Park, Macclesfield, UK
&
D. W. Roberts Drug Metabolism and Pharmacokinetics Department, AstraZeneca, Alderley Park, Macclesfield, UK
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Pages 972-985 | Received 06 Jun 2007, Accepted 09 Aug 2007, Published online: 22 Sep 2008

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E. A. Partridge, R. A. D'souza, E. M. Lenz, S. M. Smith, J. Clarkson-Jones & D. W. Roberts. (2008) Disposition and metabolism of the colchicine derivative [14C]-ZD6126 in rat and dog. Xenobiotica 38:4, pages 399-421.
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Articles from other publishers (3)

Keita Takubo, Kazunori Furutsu, Takafumi Ide, Hiroyuki Nemoto, Yuko Ueda, Kazutake Tsujikawa, Takashi Ikawa, Takehiko Yoshimitsu & Shuji Akai. (2016) Diversity Oriented Synthesis of Allocolchicinoids with Fluoro and/or Oxygen Substituent(s) on the C‐Ring from a Single Common Intermediate. European Journal of Organic Chemistry 2016:8, pages 1562-1576.
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Anthony Long. (2013) Drug metabolism in silico – the knowledge-based expert system approach. Historical perspectives and current strategies. Drug Discovery Today: Technologies 10:1, pages e147-e153.
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Eva M. Lenz. 2011. Metabolic Profiling. Metabolic Profiling 299 319 .

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