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Xenobiotica
the fate of foreign compounds in biological systems
Volume 38, 2008 - Issue 2
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Research Article

Metabolism and disposition of [14C]5-amino-o-cresol in female F344 rats and B6C3F1 mice

B. Hedtke Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA
,
Z. Gao Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA
,
L.-J. Chen Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA
,
W. M. Weber Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA
&
K. J. Dix Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108, USA
Pages 171-184 | Received 12 Sep 2007, Accepted 12 Oct 2007, Published online: 22 Sep 2008

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O. Mekenyan, S. Dimitrov, T. Pavlov, G. Dimitrova, M. Todorov, P. Petkov & S. Kotov. (2012) Simulation of chemical metabolism for fate and hazard assessment. V. Mammalian hazard assessment. SAR and QSAR in Environmental Research 23:5-6, pages 553-606.
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J. A. Skare, N. J. Hewitt, E. Doyle, R. Powrie & C. Elcombe. (2009) Metabolite screening of aromatic amine hair dyes using in vitro hepatic models. Xenobiotica 39:11, pages 811-825.
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Articles from other publishers (4)

Karen L. Blackburn, Gregory Carr, Jane L. Rose & Bastian G. Selman. (2020) An interim internal Threshold of Toxicologic Concern (iTTC) for chemicals in consumer products, with support from an automated assessment of ToxCast™ dose response data. Regulatory Toxicology and Pharmacology 114, pages 104656.
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John Manwaring, Helga Rothe, Cindy Obringer, David J. Foltz, Timothy R. Baker, John A. Troutman, Nicola J. Hewitt & Carsten Goebel. (2015) Extrapolation of systemic bioavailability assessing skin absorption and epidermal and hepatic metabolism of aromatic amine hair dyes in vitro. Toxicology and Applied Pharmacology 287:2, pages 139-148.
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Ovanes G. Mekenyan, Petko I. Petkov, Stefan V. Kotov, Stoyanka Stoeva, Verginia B. Kamenska, Sabcho D. Dimitrov, Masamitsu Honma, Makoto Hayashi, Romualdo Benigni, E. Maria Donner & Grace Patlewicz. (2012) Investigating the Relationship between in Vitro–in Vivo Genotoxicity: Derivation of Mechanistic QSAR Models for in Vivo Liver Genotoxicity and in Vivo Bone Marrow Micronucleus Formation Which Encompass Metabolism. Chemical Research in Toxicology 25:2, pages 277-296.
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C. Goebel, N.J. Hewitt, G. Kunze, M. Wenker, D.W. Hein, H. Beck & J. Skare. (2009) Skin metabolism of aminophenols: Human keratinocytes as a suitable in vitro model to qualitatively predict the dermal transformation of 4-amino-2-hydroxytoluene in vivo. Toxicology and Applied Pharmacology 235:1, pages 114-123.
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