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Xenobiotica
the fate of foreign compounds in biological systems
Volume 38, 2008 - Issue 3
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Research Article

Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug

S. C. Khojasteh Genentech, Inc., South San Francisco, CA, USA
,
D. D. Leipold Genentech, Inc., South San Francisco, CA, USA
,
F. Lai Varian, Inc., Walnut Creek, CA, USA
,
H. La Genentech, Inc., South San Francisco, CA, USA
,
M. J. Baumgardner Genentech, Inc., South San Francisco, CA, USA
,
K. E. Desino Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, KS, USA
,
O. S. Gudmundsson Bristol-Meyers Squibb, Princeton, NJ, USA
,
D. C. Bloedow University of Washington, Seattle, WA, USA
,
S. C. Bodary Schering-Plough Biopharma, Palo Alto, CA, USA
,
M. E. Reynolds Genentech, Inc., South San Francisco, CA, USA
,
T. R. Gadek SARcode Corporation, San Francisco, CA, USA
&
S. Kenkare-Mitra Genentech, Inc., South San Francisco, CA, USA
 show all
Pages 340-352 | Received 30 Sep 2007, Accepted 17 Nov 2007, Published online: 22 Sep 2008

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