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Xenobiotica
the fate of foreign compounds in biological systems
Volume 38, 2008 - Issue 5
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Research Article

Metabolism of prazosin in rat and characterization of metabolites in plasma, urine, faeces, brain and bile using liquid chromatography/mass spectrometry (LC/MS)

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Pages 540-558 | Received 19 Jan 2008, Accepted 20 Feb 2008, Published online: 22 Sep 2008

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John C. L. Erve, Chad E. Beyer, Lawrence Manzino & Rasmy E. Talaat. (2009) Metabolite identification in rat brain microdialysates by direct infusion nanoelectrospray ionization after desalting on a ZipTip and LTQ/Orbitrap mass spectrometry. Rapid Communications in Mass Spectrometry 23:24, pages 4003-4012.
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Amit S. Kalgutkar, Kosea S. Frederick, Jonathan Chupka, Bo Feng, Sarah Kempshall, Rochelle J. Mireles, Katherine S. Fenner & Matthew D. Troutman. (2009) N-(3,4-dimethoxyphenethyl)-4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2[1H]-yl)-6,7-dimethoxyquinazolin-2-amine (CP-100,356) as a “chemical knock-out equivalent” to assess the impact of efflux transporters on oral drug absorption in the rat. Journal of Pharmaceutical Sciences 98:12, pages 4914-4927.
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. (2008) Current literature in mass spectrometry. Journal of Mass Spectrometry 43:11, pages 1569-1580.
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John C. L. Erve, William DeMaio & Rasmy E. Talaat. (2008) Rapid metabolite identification with sub parts-per-million mass accuracy from biological matrices by direct infusion nanoelectrospray ionization after clean-up on a ZipTip and LTQ/Orbitrap mass spectrometry. Rapid Communications in Mass Spectrometry 22:19, pages 3015-3026.
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