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Xenobiotica
the fate of foreign compounds in biological systems
Volume 39, 2009 - Issue 2
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Research Article

Involvement of Mrp2/MRP2 in the species different excretion route of benzylpenicillin between rat and human

M.-K. ChoiNational Research Laboratory of Transporters Targeted Drug Design, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea
,
H. KimDepartment of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Busan, Korea
,
Y.-H. HanNational Research Laboratory of Transporters Targeted Drug Design, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea
,
I.-S. SongDepartment of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Busan, KoreaCorrespondence[email protected]
&
C.-K. ShimNational Research Laboratory of Transporters Targeted Drug Design, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, Korea
Pages 171-181 | Received 22 Sep 2008, Accepted 21 Nov 2008, Published online: 01 Feb 2009

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Chung-Ping Yu, Yi-Ru Wang, Yu-Chi Hou, Min-Tsang Hsieh, Pei-Ying Li, Sheng-Chu Kuo & Shiuan-Pey Lin. (2023) Two curcumin analogs inhibited the function and protein expression of breast cancer resistance protein: in vitro and in vivo studies. Xenobiotica 53:5, pages 454-464.
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Xiaoyan Chu, Kelly Bleasby & Raymond Evers. (2013) Species differences in drug transporters and implications for translating preclinical findings to humans. Expert Opinion on Drug Metabolism & Toxicology 9:3, pages 237-252.
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Articles from other publishers (13)

Xiaofen Zhao, Yangfang Li, Kun Du, Yuqin Wu, Ling Liu, Shan Cui, Yan Zhang, Jin Gao, Richard F. Keep & Jianming Xiang. (2019) Involvement of human and canine MRP1 and MRP4 in benzylpenicillin transport. PLOS ONE 14:11, pages e0225702.
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Norikazu Matsunaga, Yukina Fukuchi, Haruo Imawaka & Ikumi Tamai. (2018) Sandwich-Cultured Hepatocytes for Mechanistic Understanding of Hepatic Disposition of Parent Drugs and Metabolites by Transporter–Enzyme Interplay. Drug Metabolism and Disposition 46:5, pages 680-691.
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Yangfang Li, Qian Wu, Chen Li, Ling Liu, Kun Du, Jin Shen, Yuqin Wu, Xiaofen Zhao, Mei Zhao, Lingyun Bao, Jin Gao, Richard F. Keep & Jianming Xiang. (2016) Role of Human Breast Cancer Related Protein versus P-Glycoprotein as an Efflux Transporter for Benzylpenicillin: Potential Importance at the Blood-Brain Barrier. PLOS ONE 11:6, pages e0157576.
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Norikazu Matsunaga, Ken-ichi Nunoya, Masahiro Okada, Mikio Ogawa & Ikumi Tamai. (2013) Evaluation of Hepatic Disposition of Paroxetine Using Sandwich-Cultured Rat and Human Hepatocytes. Drug Metabolism and Disposition 41:4, pages 735-743.
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Ken Grime & Stuart W. Paine. (2013) Species Differences in Biliary Clearance and Possible Relevance of Hepatic Uptake and Efflux Transporters Involvement. Drug Metabolism and Disposition 41:2, pages 372-378.
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Han-Joo Maeng, Yu-Jin Bang & Suk-Jae Chung. (2012) Functional impairment of P-glycoprotein by sodium nitroprusside pretreatment in mouse brain capillary endothelial cells. Archives of Pharmacal Research 35:7, pages 1215-1221.
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Min-Koo Choi & Im-Sook Song. (2012) Involvement of multidrug resistance proteins (MRPs) in the efflux of vardenafil. Journal of Pharmaceutical Investigation 42:2, pages 65-70.
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Judith Naud, Louis-Philippe Laurin, Josée Michaud, Stéphanie Beauchemin, Francois A. Leblond & Vincent Pichette. (2012) Effects of Chronic Renal Failure on Brain Drug Transporters in Rats. Drug Metabolism and Disposition 40:1, pages 39-46.
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Judith Naud, Josée Michaud, Stéphanie Beauchemin, Marie-Josée Hébert, Michel Roger, Stéphane Lefrancois, Francois A. Leblond & Vincent Pichette. (2011) Effects of Chronic Renal Failure on Kidney Drug Transporters and Cytochrome P450 in Rats. Drug Metabolism and Disposition 39:8, pages 1363-1369.
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Soo Kyung Bae, Jungsug Gwak, Im-Sook Song, Hyung-Soon Park & Sangtaek Oh. (2011) Induction of apoptosis in colon cancer cells by a novel topoisomerase I inhibitor TopIn. Biochemical and Biophysical Research Communications 409:1, pages 75-81.
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Kunio Fujiwara, Masashi Shin, Tsubasa Miyazaki & Yasuhiro Maruta. (2011) Immunocytochemistry for Amoxicillin and Its Use for Studying Uptake of the Drug in the Intestine, Liver, and Kidney of Rats. Antimicrobial Agents and Chemotherapy 55:1, pages 62-71.
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Lucía González-Lobato, Rebeca Real, Julio G. Prieto, Ana I. Álvarez & Gracia Merino. (2010) Differential inhibition of murine Bcrp1/Abcg2 and human BCRP/ABCG2 by the mycotoxin fumitremorgin C. European Journal of Pharmacology 644:1-3, pages 41-48.
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Zhi‐wei Ye, Sandrine Camus, Patrick Augustijns & Pieter Annaert. (2010) Interaction of eight HIV protease inhibitors with the canalicular efflux transporter ABCC2 (MRP2) in sandwich‐cultured rat and human hepatocytes. Biopharmaceutics & Drug Disposition 31:2-3, pages 178-188.
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