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Xenobiotica
the fate of foreign compounds in biological systems
Volume 39, 2009 - Issue 7
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Research Article

Predictability of intranasal pharmacokinetics in man using pre-clinical pharmacokinetic data with a dopamine 3 receptor agonist, PF-219061

N. J. AttkinsPharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, Sandwich, UKCorrespondence[email protected]
,
A. C. HeatheringtonClinical Pharmacology, Pfizer Global Research and Development, Sandwich, UK
,
J. PhippsPharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, Sandwich, UK
,
H. VerrierMaterial Sciences, Pfizer Global Research and Development, Sandwich, UK
&
I. HuygheClinical Research Unit, Pfizer Global Research and Development, Sandwich, UK
Pages 523-533 | Received 04 Feb 2009, Accepted 13 Mar 2009, Published online: 29 May 2009

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Anthony Harrison, Iain Gardner, Tanya Hay, Maurice Dickins, Kevin Beaumont, Alex Phipps, Lynn Purkins, Gill Allan, Rachelle Christian, Jonathan Duckworth, Ian Gurrell, Sarah Kempshall, Mark Savage, Mark Seymour, Marie Simpson, Louise Taylor & Paul Turnpenny. (2012) Case studies addressing human pharmacokinetic uncertainty using a combination of pharmacokinetic simulation and alternative first in human paradigms. Xenobiotica 42:1, pages 57-74.
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Neil Attkins, Alison Betts, David Hepworth & Anne C. Heatherington. (2010) Pharmacokinetics and elucidation of the rates and routes of N-glucuronidation of PF-592379, an oral dopamine 3 agonist in rat, dog, and human. Xenobiotica 40:11, pages 730-742.
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Articles from other publishers (1)

James C. League-Pascual, Cynthia M. Lester-McCully, Shaefali Shandilya, Lukas Ronner, Louis Rodgers, Rafael Cruz, Cody J. Peer, William D. Figg & Katherine E. Warren. (2017) Plasma and cerebrospinal fluid pharmacokinetics of select chemotherapeutic agents following intranasal delivery in a non-human primate model. Journal of Neuro-Oncology 132:3, pages 401-407.
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