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Xenobiotica
the fate of foreign compounds in biological systems
Volume 39, 2009 - Issue 9
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Research Article

Comparison of intrinsic metabolic clearance in fresh and cryopreserved human hepatocytes

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Pages 656-662 | Received 17 Mar 2009, Accepted 16 Apr 2009, Published online: 13 Jul 2009

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Jaydeep Yadav, Mehdi El Hassani, Jasleen Sodhi, Volker M. Lauschke, Jessica H. Hartman & Laura E. Russell. (2021) Recent developments in in vitro and in vivo models for improved translation of preclinical pharmacokinetics and pharmacodynamics data. Drug Metabolism Reviews 53:2, pages 207-233.
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C. Desbans, C. Hilgendorf, M. Lutz, P. Bachellier, T. Zacharias, J. C. Weber, H. Dolgos, L. Richert & A.-L. Ungell. (2014) Prediction of fraction metabolized via CYP3A in humans utilizing cryopreserved human hepatocytes from a set of 12 single donors. Xenobiotica 44:1, pages 17-27.
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Sanja Juric, Patrik Lundquist, Yin Hu, Anna Juréus & Anna-Karin Sohlenius-Sternbeck. (2013) The utility of cold-preserved human hepatocytes in studies on cytochrome P450 induction and hepatic drug transport. Xenobiotica 43:9, pages 785-791.
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A.-K. Sohlenius-Sternbeck, L. Afzelius, P. Prusis, J. Neelissen, J. Hoogstraate, J. Johansson, E. Floby, A. Bengtsson, O. Gissberg, J. Sternbeck & C. Petersson. (2010) Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds. Xenobiotica 40:9, pages 637-649.
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Christine M. Bowman & Leslie Z. Benet. (2019) Interlaboratory Variability in Human Hepatocyte Intrinsic Clearance Values and Trends with Physicochemical Properties. Pharmaceutical Research 36:8.
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Robert T. Mingoia, Kyle P. Glover, Diane L. Nabb, Ching-Hui Yang, Suzanne I. Snajdr & Xing Han. (2010) Cryopreserved Hepatocytes from Rainbow Trout ( Oncorhynchus mykiss ): A Validation Study to Support Their Application in Bioaccumulation Assessment . Environmental Science & Technology 44:8, pages 3052-3058.
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Toshito Nakagawa. (2010) Prediction of the pharmacokinetics of clinical candidates in humans from in vitro data.. Folia Pharmacologica Japonica 135:2, pages 84-86.
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