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Xenobiotica
the fate of foreign compounds in biological systems
Volume 39, 2009 - Issue 8: Commemorative Issue: Professor George Gordon Gibson
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Review Article

Cynomolgus monkey CYPs: a comparison with human CYPs

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Pages 578-581 | Received 20 Apr 2009, Accepted 28 Apr 2009, Published online: 21 Jul 2009

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Zuzana E. Haarhoff, Melissa A. Kramer, Tatyana A. Zvyaga, Jun Zhang, Priyadeep Bhutani, Murali Subramanian & A. David Rodrigues. (2017) Comprehensive evaluation of liver microsomal cytochrome P450 3A (CYP3A) inhibition: comparison of cynomolgus monkey and human. Xenobiotica 47:6, pages 470-478.
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Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Takako Suzuki, Masahiro Utoh, Erika Sasaki & Hiroshi Yamazaki. (2016) Caffeine 7-N-demethylation and C-8-oxidation mediated by liver microsomal cytochrome P450 enzymes in common marmosets. Xenobiotica 46:7, pages 573-578.
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Satomi Shida, Masahiro Utoh, Norie Murayama, Makiko Shimizu, Yasuhiro Uno & Hiroshi Yamazaki. (2015) Human plasma concentrations of cytochrome P450 probes extrapolated from pharmacokinetics in cynomolgus monkeys using physiologically based pharmacokinetic modeling. Xenobiotica 45:10, pages 881-886.
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Masahiro Utoh, Norie Murayama, Yasuhiro Uno, Yui Onose, Shinya Hosaka, Hideki Fujino, Makiko Shimizu, Kazuhide Iwasaki & Hiroshi Yamazaki. (2013) Monkey liver cytochrome P450 2C9 is involved in caffeine 7-N-demethylation to form theophylline. Xenobiotica 43:12, pages 1037-1042.
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Noriaki Yoda, Chie Emoto, Shoichi Date, Satoshi Kondo, Masateru Miyake, Satoru Nakazato, Ken Umehara & Eiji Kashiyama. (2012) Characterization of intestinal and hepatic P450 enzymes in cynomolgus monkeys with typical substrates and inhibitors for human P450 enzymes. Xenobiotica 42:8, pages 719-730.
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Yasuhiro Uno, Kazuhide Iwasaki, Hiroshi Yamazaki & David R. Nelson. (2011) Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function. Drug Metabolism Reviews 43:3, pages 346-361.
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