Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 39, 2009 - Issue 8: Commemorative Issue: Professor George Gordon Gibson
145
Views
23
CrossRef citations to date
0
Altmetric
Review Article

Nuclear receptors: the controlling force in drug metabolism of the liver?

&
Pages 597-605 | Accepted 08 Jun 2009, Published online: 21 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Martin Chopra & Dieter Schrenk. (2011) Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis—Persistent pollutants affect programmed cell death. Critical Reviews in Toxicology 41:4, pages 292-320.
Read now
. (2010) Invited Speakers. Drug Metabolism Reviews 42:sup1, pages 1-323.
Read now

Articles from other publishers (20)

Yasin KIRTIL & Murat KANBUR. (2023) Nükleer ReseptörlerNuclear Receptors. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 20:1, pages 64-71.
Crossref
John R. Foster, Giovanna Semino-Beninel & Stephanie Melching-Kollmuss. (2020) The Cumulative Risk Assessment of Hepatotoxic Chemicals: A Hepatic Histopathology Perspective. Toxicologic Pathology 48:3, pages 397-410.
Crossref
Madalena V.F. Real, Maria J. Rocha, José F. Gonçalves & Eduardo Rocha. (2020) Histology and design-based estimation of hepatocellularity and volumes of hepatocytes in control and ethynylestradiol exposed males of platyfish (Xiphophorus maculatus). Tissue and Cell 63, pages 101327.
Crossref
Joanna H. Sier, Alfred E. Thumser & Nick J. Plant. (2017) Linking physiologically-based pharmacokinetic and genome-scale metabolic networks to understand estradiol biology. BMC Systems Biology 11:1.
Crossref
Elaina M. Maldonado, Vytautas Leoncikas, Ciarán P. Fisher, J. Bernadette Moore, Nick J. Plant & Andrzej M. Kierzek. (2017) Integration of Genome Scale Metabolic Networks and Gene Regulation of Metabolic Enzymes With Physiologically Based Pharmacokinetics. CPT: Pharmacometrics & Systems Pharmacology 6:11, pages 732-746.
Crossref
Nick Plant. (2017) Can a systems approach produce a better understanding of mood disorders?. Biochimica et Biophysica Acta (BBA) - General Subjects 1861:1, pages 3335-3344.
Crossref
Noura Alasmael, Rati Mohan, Lisiane B. Meira, Karen E. Swales & Nick J. Plant. (2016) Activation of the Farnesoid X-receptor in breast cancer cell lines results in cytotoxicity but not increased migration potential. Cancer Letters 370:2, pages 250-259.
Crossref
Nick Plant. (2015) Molecular biology I: transcriptional regulation. Surgery (Oxford) 33:3, pages 95-98.
Crossref
Nick Plant. (2015) Molecular biology II: protein function. Surgery (Oxford) 33:3, pages 99-103.
Crossref
Alexey Kolodkin, Nilgun Sahin, Anna Phillips, Steve R. Hood, Frank J. Bruggeman, Hans V. Westerhoff & Nick Plant. (2013) Optimization of stress response through the nuclear receptor-mediated cortisol signalling network. Nature Communications 4:1.
Crossref
Stefano Lorenzetti*Laura Narciso. 2012. Computational Approaches to Nuclear Receptors. Computational Approaches to Nuclear Receptors 1 22 .
A. P. Hall, C. R. Elcombe, J. R. Foster, T. Harada, W. Kaufmann, A. Knippel, K. Küttler, D. E. Malarkey, R. R. Maronpot, A. Nishikawa, T. Nolte, A. Schulte, V. Strauss & M. J. York. (2012) Liver Hypertrophy. Toxicologic Pathology 40:7, pages 971-994.
Crossref
Fadheela Al-Salman & Nick Plant. (2012) Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in a tissue-specific manner. Toxicology and Applied Pharmacology 263:1, pages 7-13.
Crossref
Nick Plant. (2012) Molecular biology II: protein function. Surgery (Oxford) 30:4, pages 169-173.
Crossref
Nick Plant. (2012) Molecular biology I: transcriptional regulation. Surgery (Oxford) 30:4, pages 165-168.
Crossref
Alexander V. LyubimovEmily A. Fraser, Colin J. Henderson & C. Roland Wolf. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions 1 34 .
Supaporn Yimthaing, Nick Plant & Kate Plant. (2011) Regulation of nuclear import pathways by vitamin D signalling: Potential biological implications. Toxicology 290:2-3, pages 132.
Crossref
Alexey N. Kolodkin, Frank J. Bruggeman, Nick Plant, Martijn J. Moné, Barbara M. Bakker, Moray J. Campbell, Johannes P.T.M. van Leeuwen, Carsten Carlberg, Jacky L. Snoep & Hans V. Westerhoff. (2011) Design principles of nuclear receptor signalling: How complex networking improves signal transduction. Toxicology 290:2-3, pages 131-132.
Crossref
Alexey N. Kolodkin, Anna Phillips, Steve Hood, Frank J. Bruggeman, Hans V. Westerhoff & Nick Plant. (2011) A systems biology approach towards understanding nuclear receptor interactions: Implications at the endocrine–xenobiotic signalling interface. Toxicology 290:2-3, pages 131.
Crossref
Ian Bailey, G. Gordon Gibson, Kathryn Plant, Mark Graham & Nick Plant. (2011) A PXR-Mediated Negative Feedback Loop Attenuates the Expression of CYP3A in Response to the PXR Agonist Pregnenalone-16α-Carbonitrile. PLoS ONE 6:2, pages e16703.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.