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Xenobiotica
the fate of foreign compounds in biological systems
Volume 39, 2009 - Issue 8: Commemorative Issue: Professor George Gordon Gibson
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Review Article

Cell death pathways – potential therapeutic targets

Pages 616-624 | Accepted 24 Jun 2009, Published online: 21 Jul 2009

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R. Vidya Priyadarsini, R. Senthil Murugan, P. Sripriya, D. Karunagaran & S. Nagini. (2010) The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells. Free Radical Research 44:6, pages 624-634.
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Jieyan Wang, Yingling Wang, Shihan He, Zhu Wang, Qiong Deng & Hui Liang. (2021) Proteasome inhibition induces macrophage apoptosis via mitochondrial dysfunction. Journal of Biochemical and Molecular Toxicology 35:11.
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Nina G. Morozova, Elena V. Shmendel, Grigory A. Timofeev, Igor V. Ivanov, Tatyana S. Kubasova, Natalia V. Plyavnik, Alina A. Markova, Mikhail A. Maslov & Alexander A. Shtil. (2019) New design of cationic alkyl glycoglycerolipids toxic to tumor cells. Mendeleev Communications 29:2, pages 166-168.
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Raghavendra Subbarao, Seong-Ho Ok, Soo Lee, Dawon Kang, Eun-Jin Kim, Ji-Yoon Kim & Ju-Tae Sohn. (2018) Lipid Emulsion Inhibits the Late Apoptosis/Cardiotoxicity Induced by Doxorubicin in Rat Cardiomyoblasts. Cells 7:10, pages 144.
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Zahra Shariatinia & Azin Mazloom Jalali. (2018) Chitosan-based hydrogels: Preparation, properties and applications. International Journal of Biological Macromolecules 115, pages 194-220.
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Yawei Li, Na Xu, Wenhe Zhu, Lei Wang, Bin Liu, Jianxu Zhang, Zhigang Xie & Wensen Liu. (2018) Nanoscale Melittin@Zeolitic Imidazolate Frameworks for Enhanced Anticancer Activity and Mechanism Analysis. ACS Applied Materials & Interfaces 10:27, pages 22974-22984.
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Temilolu Idowu, Pranati Samadder, Gilbert Arthur & Frank Schweizer. (2017) Amphiphilic Modulation of Glycosylated Antitumor Ether Lipids Results in a Potent Triamino Scaffold against Epithelial Cancer Cell Lines and BT474 Cancer Stem Cells. Journal of Medicinal Chemistry 60:23, pages 9724-9738.
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S-H Ok, J Yu, Y Lee, H Cho, I-W Shin & J-T Sohn. (2016) Lipid emulsion attenuates apoptosis induced by a toxic dose of bupivacaine in H9c2 rat cardiomyoblast cells. Human & Experimental Toxicology 35:9, pages 929-937.
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Temilolu Idowu, Pranati Samadder, Gilbert Arthur & Frank Schweizer. (2016) Design, synthesis and antitumor properties of glycosylated antitumor ether lipid (GAEL)- chlorambucil-hybrids. Chemistry and Physics of Lipids 194, pages 139-148.
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Claudia Langlais, Michelle A. Hughes, Kelvin Cain & Marion MacFarlane. (2015) Biochemical Analysis of Initiator Caspase-Activating Complexes: The Apoptosome and the Death-Inducing Signaling Complex. Cold Spring Harbor Protocols 2015:12, pages pdb.top070326.
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L Galluzzi, J M Bravo-San Pedro, I Vitale, S A Aaronson, J M Abrams, D Adam, E S Alnemri, L Altucci, D Andrews, M Annicchiarico-Petruzzelli, E H Baehrecke, N G Bazan, M J Bertrand, K Bianchi, M V Blagosklonny, K Blomgren, C Borner, D E Bredesen, C Brenner, M Campanella, E Candi, F Cecconi, F K Chan, N S Chandel, E H Cheng, J E Chipuk, J A Cidlowski, A Ciechanover, T M Dawson, V L Dawson, V De Laurenzi, R De Maria, K-M Debatin, N Di Daniele, V M Dixit, B D Dynlacht, W S El-Deiry, G M Fimia, R A Flavell, S Fulda, C Garrido, M-L Gougeon, D R Green, H Gronemeyer, G Hajnoczky, J M Hardwick, M O Hengartner, H Ichijo, B Joseph, P J Jost, T Kaufmann, O Kepp, D J Klionsky, R A Knight, S Kumar, J J Lemasters, B Levine, A Linkermann, S A Lipton, R A Lockshin, C López-Otín, E Lugli, F Madeo, W Malorni, J-C Marine, S J Martin, J-C Martinou, J P Medema, P Meier, S Melino, N Mizushima, U Moll, C Muñoz-Pinedo, G Nuñez, A Oberst, T Panaretakis, J M Penninger, M E Peter, M Piacentini, P Pinton, J H Prehn, H Puthalakath, G A Rabinovich, K S Ravichandran, R Rizzuto, C M Rodrigues, D C Rubinsztein, T Rudel, Y Shi, H-U Simon, B R Stockwell, G Szabadkai, S W Tait, H L Tang, N Tavernarakis, Y Tsujimoto, T Vanden Berghe, P Vandenabeele, A Villunger, E F Wagner, H Walczak, E White, W G Wood, J Yuan, Z Zakeri, B Zhivotovsky, G Melino & G Kroemer. (2014) Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death & Differentiation 22:1, pages 58-73.
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Pranati Samadder, Yaozu Xu, Frank Schweizer & Gilbert Arthur. (2014) Cytotoxic properties of d-gluco-, d-galacto- and d-manno-configured 2-amino-2-deoxy-glycerolipids against epithelial cancer cell lines and BT-474 breast cancer stem cells. European Journal of Medicinal Chemistry 78, pages 225-235.
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Lei Wang, Tingjun Ye, Lianfu Deng, Jin Shao, Jin Qi, Qi Zhou, Li Wei & Shijing Qiu. (2014) Repair of Microdamage in Osteonal Cortical Bone Adjacent to Bone Screw. PLoS ONE 9:2, pages e89343.
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Qingdi Quentin Li, Rebecca X. Lee, Huasheng Liang, Yuhua Zhong & Eddie Reed. (2013) Enhancement of cisplatin-induced apoptosis by β-elemene in resistant human ovarian cancer cells. Medical Oncology 30:1.
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Yaozu Xu, Makanjuola Ogunsina, Pranati Samadder, Gilbert Arthur & Frank Schweizer. (2013) Structure-Activity Relationships of Glucosamine-Derived Glycerolipids: the Role of the Anomeric Linkage, the Cationic Charge and the Glycero Moiety on the Antitumor Activity. ChemMedChem 8:3, pages 511-520.
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Simon Chiu, Kristen J. Terpstra, Yves Bureau, Jirui Hou, Hana Raheb, Zack Cernvosky, Vladimir Badmeav, John Copen, Mariwan Husni & Michael Woodbury-Farina. (2013) Liposomal-formulated curcumin [Lipocurc™] targeting HDAC (Histone Deacetylase) prevents apoptosis and improves motor deficits in Park 7 (DJ-1)-knockout rat model of Parkinson’s disease: implications for epigenetics-based nanotechnology-driven drug platform. Journal of Complementary and Integrative Medicine 10:1.
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Palrasu Manikandan, Senthil Murugan Ramalingam, Govindarajah Vinothini, Vidya Priyadarsini Ramamurthi, Inder Pal Singh, Rangasamy Anandan, Mannathusamy Gopalakrishnan & Siddavaram Nagini. (2012) Investigation of the chemopreventive potential of neem leaf subfractions in the hamster buccal pouch model and phytochemical characterization. European Journal of Medicinal Chemistry 56, pages 271-281.
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Soo-Young Lee, Ilja Peckermann, Elise Abinet, Jun Okuda, Günter Henze & Aram Prokop. (2010) The rare-earth yttrium complex [YR(mtbmp)(thf)] triggers apoptosis via the extrinsic pathway and overcomes multiple drug resistance in leukemic cells. Medical Oncology 29:1, pages 235-242.
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L. Kater, J. Claffey, M. Hogan, P. Jesse, B. Kater, S. Strauß, M. Tacke & A. Prokop. (2012) The role of the intrinsic FAS pathway in Titanocene Y apoptosis: The mechanism of overcoming multiple drug resistance in malignant leukemia cells. Toxicology in Vitro 26:1, pages 119-124.
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Stuart M. Flechner,James H. Finke,Robert L. Fairchild,. 2012. Campbell-Walsh Urology. Campbell-Walsh Urology 495 529.e5 .
H P Rang, M M Dale, J M Ritter, R J Flower & G Henderson. 2012. Rang &amp Dale's Pharmacology. Rang &amp Dale's Pharmacology 66 76 .
Xinbo Zhang, Naimei Tang, Timothy J. Hadden & Arun K. Rishi. (2011) Akt, FoxO and regulation of apoptosis. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1813:11, pages 1978-1986.
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B Ma, T Sen, L Asnaghi, M Valapala, F Yang, S Hose, D S McLeod, Y Lu, C Eberhart, J S ZiglerJrJr & D Sinha. (2011) βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis. Cell Death & Disease 2:10, pages e217-e217.
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Paul J. Smith, Roy Edward & Rachel J. Errington. 2010. Flow Cytometry in Drug Discovery and Development. Flow Cytometry in Drug Discovery and Development 23 54 .
R. Senthil Murugan, R. Vidya Priyadarsini, K. Ramalingam, Y. Hara, D. Karunagaran & S. Nagini. (2010) Intrinsic apoptosis and NF-κB signaling are potential molecular targets for chemoprevention by black tea polyphenols in HepG2 cells in vitro and in a rat hepatocarcinogenesis model in vivo. Food and Chemical Toxicology 48:11, pages 3281-3287.
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Giridhar Thiagarajan, Abhijit Ray, Alexander Malugin & Hamidreza Ghandehari. (2010) PAMAM-Camptothecin Conjugate Inhibits Proliferation and Induces Nuclear Fragmentation in Colorectal Carcinoma Cells. Pharmaceutical Research 27:11, pages 2307-2316.
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Robert S. Boyd, Martin J.S. Dyer & Kelvin Cain. (2010) Proteomic analysis of B-cell malignancies. Journal of Proteomics 73:10, pages 1804-1822.
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G.A. dos Santos, C.H. Thomé, G.A. Ferreira, J.S. Yoneda, T.M. Nobre, K.R.P. Daghastanli, P.S. Scheucher, H.L. Gimenes-Teixeira, M.G. Constantino, K.T. de Oliveira, V.M. Faça, R.P. Falcão, L.J. Greene, E.M. Rego & P. Ciancaglini. (2010) Interaction of 10-(octyloxy) decyl-2-(trimethylammonium) ethyl phosphate with mimetic membranes and cytotoxic effect on leukemic cells. Biochimica et Biophysica Acta (BBA) - Biomembranes 1798:9, pages 1714-1723.
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Palrasu Manikandan, Ramalingam Senthil Murugan, Ramamurthi Vidya Priyadarsini, Govindarajah Vinothini & Siddavaram Nagini. (2010) Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG. Life Sciences 86:25-26, pages 936-941.
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