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Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 4
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General Xenobiochemistry

In vitro characterization of belinostat glucuronidation: demonstration of both UGT1A1 and UGT2B7 as the main contributing isozymes

Dong DongOcular Surface Research Center and Institute of Ophthalmology, Jinan University School of Medicine, Guangzhou, China,
,
Tianpeng ZhangResearch Center for Biopharmaceutics and Pharmacokinetics, College of Pharmacy, Jinan University, Guangzhou, China, and
,
Danyi LuResearch Center for Biopharmaceutics and Pharmacokinetics, College of Pharmacy, Jinan University, Guangzhou, China, and
,
Jie LiuDepartment of Pharmacy, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
&
Baojian WuResearch Center for Biopharmaceutics and Pharmacokinetics, College of Pharmacy, Jinan University, Guangzhou, China, and Correspondence[email protected]
Pages 277-283 | Received 06 Apr 2016, Accepted 22 Apr 2016, Published online: 16 May 2016

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Feng Li, Shuai Wang, Danyi Lu, Yifei Wang, Dong Dong & Baojian Wu. (2017) Identification of UDP-glucuronosyltransferases 1A1, 1A3 and 2B15 as the main contributors to glucuronidation of bakuchiol, a natural biologically active compound. Xenobiotica 47:5, pages 369-375.
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Articles from other publishers (7)

Cui-Lan Meng, Wei Zhao & Dan-Ni Zhong. (2021) Epigenetics and microRNAs in UGT1As. Human Genomics 15:1.
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Donald J. AbrahamDeepak K. Dalvie & Bernard Testa. 2003. Burger's Medicinal Chemistry and Drug Discovery. Burger's Medicinal Chemistry and Drug Discovery 1 139 .
Ryan S. Nelson, Nathan D. Seligson, Sal Bottiglieri, Estrella Carballido, Alex Del Cueto, Iman Imanirad, Richard Levine, Alexander S. Parker, Sandra M. Swain, Emma M. Tillman & J. Kevin Hicks. (2021) UGT1A1 Guided Cancer Therapy: Review of the Evidence and Considerations for Clinical Implementation. Cancers 13:7, pages 1566.
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Xiaoyu Wang, Zhe Wang, Zhen Wang, Xiuyuan Chen, Hang Yin, Lili Jiang, Jun Cao & Yong Liu. (2021) Inhibition of human UDP-glucuronosyltransferase enzyme by belinostat: Implications for drug-drug interactions. Toxicology Letters 338, pages 51-57.
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Naoko Takebe, Jan H. Beumer, Shivaani Kummar, Brian F. Kiesel, Afshin Dowlati, Geraldine O'Sullivan Coyne, Richard Piekarz, Lawrence Rubinstein, Laura K. Fogli, Ulka Vaishampayan, Sanjay Goel, Cindy L. O'Bryant, Bassel F. El‐Rayes, Vincent Chung, Heinz‐Josef Lenz, Richard Kim, Chandra P. Belani, Joseph M. Tuscano, William Schelman, Nancy Moore, James H. Doroshow & Alice P. Chen. (2019) A phase I pharmacokinetic study of belinostat in patients with advanced cancers and varying degrees of liver dysfunction. British Journal of Clinical Pharmacology 85:11, pages 2499-2511.
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Tianpeng Zhang, Lianxia Guo, Fangjun Yu, Min Chen & Baojian Wu. (2019) The nuclear receptor Rev-erbα participates in circadian regulation of Ugt2b enzymes in mice. Biochemical Pharmacology 161, pages 89-97.
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Rashmi R. Shah. (2019) Safety and Tolerability of Histone Deacetylase (HDAC) Inhibitors in Oncology. Drug Safety 42:2, pages 235-245.
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