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Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 7
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General Xenobiochemistry

Marmoset cytochrome P450 4A11, a novel arachidonic acid and lauric acid ω-hydroxylase expressed in liver and kidney tissues

Shotaro UeharaLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan,
,
Yasuhiro UnoPharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd, Kainan, Wakayama, Japan,
,
Sakura IshiiLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan,
,
Takashi InoueCentral Institute for Experimental Animals, Kawasaki, Japan, and
,
Erika SasakiCentral Institute for Experimental Animals, Kawasaki, Japan, and ;Keio Advanced Research Center, Keio University, Minato-ku, Tokyo, Japan
&
Hiroshi YamazakiLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan, Correspondence[email protected]
Pages 553-561 | Received 26 May 2016, Accepted 23 Jun 2016, Published online: 20 Jul 2016

Citations (15)

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Read on this site (4)

Yasuhiro Uno & Hiroshi Yamazaki. (2020) Expression levels of microRNAs that are potential cytochrome P450 regulators in cynomolgus macaques. Xenobiotica 50:7, pages 747-752.
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Kazuyuki Nakanishi, Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2018) Progesterone hydroxylation by cytochromes P450 2C and 3A enzymes in marmoset liver microsomes. Xenobiotica 48:8, pages 757-763.
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Yasuhiro Uno & Hiroshi Yamazaki. (2018) Expression of cytochrome P450 regulators in cynomolgus macaque. Xenobiotica 48:7, pages 695-703.
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Shotaro Uehara, Yukako Yuki, Yasuhiro Uno, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2018) Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines. Xenobiotica 48:4, pages 342-347.
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Articles from other publishers (11)

Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. 2022. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary 329 364 .
Shotaro Uehara, Yasuhiro Uno & Hiroshi Yamazaki. (2020) Molecular cloning and tissue distribution of marmoset thiopurine S-methyltransferase. Drug Metabolism and Pharmacokinetics 35:5, pages 475-478.
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Rajagopal N. Aravalli & Clifford J. Steer. (2020) Utility of Common Marmoset (Callithrix jacchus) Embryonic Stem Cells in Liver Disease Modeling, Tissue Engineering and Drug Metabolism. Genes 11:7, pages 729.
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Waranya Chatuphonprasert, Nawaratt Nawaratt & Kanokwan Jarukamjorn. (2020) Reused palm oil from frying pork or potato induced expression of cytochrome P450s and the SLCO1B1 transporter in HepG2 cells . Journal of Food Biochemistry 44:5.
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Yasuhiro Uno & Hiroshi Yamazaki. (2020) mRNA levels of drug-metabolizing enzymes in 11 brain regions of cynomolgus macaques. Drug Metabolism and Pharmacokinetics 35:2, pages 248-252.
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Shotaro Uehara, Yasuhiro Uno & Hiroshi Yamazaki. (2020) The marmoset cytochrome P450 superfamily: Sequence/phylogenetic analyses, genomic structure, and catalytic function. Biochemical Pharmacology 171, pages 113721.
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Shotaro Uehara, Toru Oshio, Kazuyuki Nakanishi, Etsuko Tomioka, Miyu Suzuki, Takashi Inoue, Yasuhiro Uno, Erika Sasaki & Hiroshi Yamazaki. (2019) Survey of Drug Oxidation Activities in Hepatic and Intestinal Microsomes of Individual Common Marmosets, a New Nonhuman Primate Animal Model. Current Drug Metabolism 20:2, pages 103-113.
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Kazuyuki Nakanishi, Shotaro Uehara, Takashi Kusama, Takashi Inoue, Kanami Shimura, Yusuke Kamiya, Norie Murayama, Makiko Shimizu, Yasuhiro Uno, Erika Sasaki & Hiroshi Yamazaki. (2018) In vivo and in vitro diclofenac 5-hydroxylation mediated primarily by cytochrome P450 3A enzymes in common marmoset livers genotyped for P450 2C19 variants. Biochemical Pharmacology 152, pages 272-278.
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Shotaro Uehara, Sakura Ishii, Yasuhiro Uno, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2017) Regio- and Stereo-Selective Oxidation of a Cardiovascular Drug, Metoprolol, Mediated by Cytochrome P450 2D and 3A Enzymes in Marmoset Livers. Drug Metabolism and Disposition 45:8, pages 896-899.
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Shotaro Uehara, Makiko Shimizu, Yasuhiro Uno, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2017) Marmoset Flavin-Containing Monooxygenase 3 in the Liver Is a Major Benzydamine and Sulindac Sulfide Oxygenase. Drug Metabolism and Disposition 45:5, pages 497-500.
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Shotaro Uehara, Yasuhiro Uno, Kazuyuki Nakanishi, Sakura Ishii, Takashi Inoue, Erika Sasaki & Hiroshi Yamazaki. (2017) Marmoset Cytochrome P450 3A4 Ortholog Expressed in Liver and Small-Intestine Tissues Efficiently Metabolizes Midazolam, Alprazolam, Nifedipine, and Testosterone. Drug Metabolism and Disposition 45:5, pages 457-467.
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