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Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 12
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General Xenobiochemistry

Effect of piperine on CYP2E1 enzyme activity of chlorzoxazone in healthy volunteers

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Pages 1035-1041 | Received 24 Jul 2016, Accepted 22 Sep 2016, Published online: 16 Nov 2016

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Read on this site (3)

Suraj S. Yadav, Manish K. Singh, Sartaj Hussain, Pradeep Dwivedi, Sanjay Khattri & Kuldeep Singh. (2023) Therapeutic spectrum of piperine for clinical practice: a scoping review. Critical Reviews in Food Science and Nutrition 63:22, pages 5813-5840.
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Christian Rafael Quijia & Marlus Chorilli. (2020) Characteristics, Biological Properties and Analytical Methods of Piperine: A Review. Critical Reviews in Analytical Chemistry 50:1, pages 62-77.
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Tianjing Ren & Zhong Zuo. (2019) Role of piperine in CNS diseases: pharmacodynamics, pharmacokinetics and drug interactions. Expert Opinion on Drug Metabolism & Toxicology 15:10, pages 849-867.
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Articles from other publishers (11)

B R Pradeepa, T.M. Vijayakumar, K. Manikandan & Ananth Kumar Kammala. (2023) Cytochrome P450-mediated alterations in clinical pharmacokinetic parameters of conventional drugs co-administered with piperine: A systematic review and meta-analysis. Journal of Herbal Medicine, pages 100713.
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Amit Kumar Tripathi, Anup Kumar Ray & Sunil Kumar Mishra. (2022) Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials. Beni-Suef University Journal of Basic and Applied Sciences 11:1.
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Rashmi Singh, Haamid Rasheed, Suhail Ahmed, Harjeet Singh & Alok Sharma. 2022. Chemistry, Biological Activities and Therapeutic Applications of Medicinal Plants in Ayurveda. Chemistry, Biological Activities and Therapeutic Applications of Medicinal Plants in Ayurveda 148 175 .
Santosh Kumar, Bhupesh Singla, Ajay K. Singh, Stacey M. Thomas-Gooch, Kaining Zhi & Udai P. Singh. (2022) Hepatic, Extrahepatic and Extracellular Vesicle Cytochrome P450 2E1 in Alcohol and Acetaminophen-Mediated Adverse Interactions and Potential Treatment Options. Cells 11:17, pages 2620.
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Shipra Bhatt, Diksha Manhas, Vinay Kumar, Abhishek Gour, Kuhu Sharma, Ashish Dogra, Probir Kumar Ojha & Utpal Nandi. (2022) Effect of Myricetin on CYP2C8 Inhibition to Assess the Likelihood of Drug Interaction Using In Silico , In Vitro , and In Vivo Approaches . ACS Omega 7:15, pages 13260-13269.
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Sreemoyee Chatterjee, Shalini Jain, Ritu Jangid & Mukesh Kumar Sharma. 2022. 225 258 .
Rainer Ziegenhagen, Katharina Heimberg, Alfonso Lampen & Karen Ildico Hirsch-Ernst. (2021) Safety Aspects of the Use of Isolated Piperine Ingested as a Bolus. Foods 10:9, pages 2121.
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Hyung-Ju Seo, Seung-Bae Ji, Sin-Eun Kim, Gyung-Min Lee, So-Young Park, Zhexue Wu, Dae Sik Jang & Kwang-Hyeon Liu. (2021) Inhibitory Effects of Schisandra Lignans on Cytochrome P450s and Uridine 5′-Diphospho-Glucuronosyl Transferases in Human Liver Microsomes. Pharmaceutics 13:3, pages 371.
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Zorica Stojanović-Radić, Milica Pejčić, Marina Dimitrijević, Ana Aleksić, Nanjangud V. Anil Kumar, Bahare Salehi, William C. Cho & Javad Sharifi-Rad. (2019) Piperine-A Major Principle of Black Pepper: A Review of Its Bioactivity and Studies. Applied Sciences 9:20, pages 4270.
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Rolf Teschke. (2018) Alcoholic Liver Disease: Alcohol Metabolism, Cascade of Molecular Mechanisms, Cellular Targets, and Clinical Aspects. Biomedicines 6:4, pages 106.
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Satish Kumar Bedada & Prasad Neerati. (2017) The effect of quercetin on the pharmacokinetics of chlorzoxazone, a CYP2E1 substrate, in healthy subjects. European Journal of Clinical Pharmacology 74:1, pages 91-97.
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