Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines

Shotaro UeharaLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan,

Yukako YukiLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan,

Yasuhiro UnoPharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd., Kainan, Wakayama, Japan,

Takashi InoueDepartment of Applied Developmental Biology, Central Institute for Experimental Animals, Kawasaki, Japan, and

Erika SasakiDepartment of Applied Developmental Biology, Central Institute for Experimental Animals, Kawasaki, Japan, and ;Keio Advanced Research Center, Keio University, Minato-ku, Tokyo, Japan

Hiroshi YamazakiLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan, Correspondence[email protected]

http://orcid.org/0000-0002-1068-4261

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Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines

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Terfenadine t-butyl hydroxylation catalyzed by human and marmoset cytochrome P450 3A and 4F enzymes in livers and small intestines

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