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Xenobiotica
the fate of foreign compounds in biological systems
Volume 48, 2018 - Issue 7
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General Xenobiochemistry

Induction of human cytochrome P450 3A4 by the irreversible myeloperoxidase inactivator PF-06282999 is mediated by the pregnane X receptor

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Pages 647-655 | Received 25 Jun 2017, Accepted 05 Jul 2017, Published online: 24 Jul 2017

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Motoyasu Miura, Shinya Uchida, Shimako Tanaka, Chiaki Kamiya, Naoki Katayama, Akio Hakamata, Keiichi Odagiri, Naoki Inui, Junichi Kawakami, Hiroshi Watanabe & Noriyuki Namiki. (2021) Verification of a cocktail approach for quantitative drug–drug interaction assessment: a comparative analysis between the results of a single drug and a cocktail drug. Xenobiotica 51:4, pages 404-412.
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Tord Inghardt, Thomas Antonsson, Cecilia Ericsson, Daniel Hovdal, Petra Johannesson, Carina Johansson, Ulrik Jurva, Johan Kajanus, Bengt Kull, Erik Michaëlsson, Anna Pettersen, Tove Sjögren, Henrik Sörensen, Kristina Westerlund & Eva-Lotte Lindstedt. (2022) Discovery of AZD4831, a Mechanism-Based Irreversible Inhibitor of Myeloperoxidase, As a Potential Treatment for Heart Failure with Preserved Ejection Fraction. Journal of Medicinal Chemistry 65:17, pages 11485-11496.
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Sophie L. Maiocchi, Jacqueline Ku, Thuan Thai, Enoch Chan, Martin D. Rees & Shane R. Thomas. (2021) Myeloperoxidase: A versatile mediator of endothelial dysfunction and therapeutic target during cardiovascular disease. Pharmacology & Therapeutics 221, pages 107711.
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Congrong Niu, Yujin Wang, Xiaofeng Zhao, Sam Tep, Eisuke Murakami, Raju Subramanian, Bill Smith & Yurong Lai. (2019) Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo. Drug Metabolism and Disposition 47:12, pages 1433-1442.
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Camilla Bernasconi, Olavi Pelkonen, Tommy B. Andersson, Judy Strickland, Iwona Wilk-Zasadna, David Asturiol, Thomas Cole, Roman Liska, Andrew Worth, Ursula Müller-Vieira, Lysiane Richert, Christophe Chesne & Sandra Coecke. (2019) Validation of in vitro methods for human cytochrome P450 enzyme induction: Outcome of a multi-laboratory study. Toxicology in Vitro 60, pages 212-228.
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Tingting Li, Sida Jiang, Bingwei Ni, Qiuji Cui, Qinan Liu & Hongping Zhao. (2019) Discontinued Drugs for the Treatment of Cardiovascular Disease from 2016 to 2018. International Journal of Molecular Sciences 20:18, pages 4513.
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Alexander V. Dmitriev, Alexey A. Lagunin, Dmitry А. Karasev, Anastasia V. Rudik, Pavel V. Pogodin, Dmitry A. Filimonov & Vladimir V. Poroikov. (2019) Prediction of Drug-Drug Interactions Related to Inhibition or Induction of Drug-Metabolizing Enzymes. Current Topics in Medicinal Chemistry 19:5, pages 319-336.
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