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Xenobiotica
the fate of foreign compounds in biological systems
Volume 48, 2018 - Issue 12
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Clinical Pharmacokinetics and Metabolism

Plasma concentrations of cytisine, a commercially available plant-based alkaloid, in healthy adult smokers taking recommended doses for smoking cessation

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Pages 1245-1248 | Received 19 Oct 2017, Accepted 22 Nov 2017, Published online: 12 Dec 2017

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Soo Hee Jeong, Janie Sheridan, Chris Bullen, David Newcombe, Natalie Walker & Malcolm Tingle. (2019) Ascending single dose pharmacokinetics of cytisine in healthy adult smokers. Xenobiotica 49:11, pages 1332-1337.
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Karol Wróblewski, Julia Wojnicka, Piotr Tutka, Agnieszka Szmagara & Anna Błażewicz. (2024) Measurements of cadmium levels in relation to tobacco dependence and as a function of cytisine administration. Scientific Reports 14:1.
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Karol Wróblewski, Małgorzata Szultka-Młyńska, Ryan J. Courtney, Bogusław Buszewski & Piotr Tutka. (2023) Development and Validation of LC-MS/MS Method for Determination of Cytisine in Human Serum and Saliva. International Journal of Molecular Sciences 24:20, pages 15364.
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Aaron L Nichols, Zack Blumenfeld, Chengcheng Fan, Laura Luebbert, Annet EM Blom, Bruce N Cohen, Jonathan S Marvin, Philip M Borden, Charlene H Kim, Anand K Muthusamy, Amol V Shivange, Hailey J Knox, Hugo Rego Campello, Jonathan H Wang, Dennis A Dougherty, Loren L Looger, Timothy Gallagher, Douglas C Rees & Henry A Lester. (2022) Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands. eLife 11.
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Mitchell Nides, Nancy A Rigotti, Neal Benowitz, Anthony Clarke & Cindy Jacobs. (2021) A Multicenter, Double-Blind, Randomized, Placebo-Controlled Phase 2b Trial of Cytisinicline in Adult Smokers (The ORCA-1 Trial). Nicotine & Tobacco Research 23:10, pages 1656-1663.
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Karol Wróblewski, Anna Petruczynik, Tomasz Tuzimski, Dominika Przygodzka, Grzegorz Buszewicz, Patrycjusz Kołodziejczyk & Piotr Tutka. (2019) Comparison of Various Chromatographic Systems for Analysis of Cytisine in Human Serum, Saliva and Pharmaceutical Formulation by HPLC with Diode Array, Fluorescence or Mass Spectrometry Detection. Molecules 24:14, pages 2580.
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Hans Rollema & Raymond S. Hurst. (2018) The contribution of agonist and antagonist activities of α4β2* nAChR ligands to smoking cessation efficacy: a quantitative analysis of literature data. Psychopharmacology 235:9, pages 2479-2505.
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