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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 1
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Clinical Pharmacokinetics and Metabolism

Absorption, distribution, metabolism, and excretion of mTOR kinase inhibitor CC-223 in rats, dogs, and humans

Zeen TongNonclinical Development, Celgene Corporation, Summit, NJ, USA and Correspondence[email protected]
,
Christian AtsrikuNonclinical Development, Celgene Corporation, Summit, NJ, USA and
,
Usha YerramilliNonclinical Development, Celgene Corporation, Summit, NJ, USA and
,
Xiaomin WangNonclinical Development, Celgene Corporation, Summit, NJ, USA and
,
Jim NisselClinical Pharmacology, Celgene Corporation, Summit, NJ, USA
,
Yan LiClinical Pharmacology, Celgene Corporation, Summit, NJ, USA
&
Sekhar SurapaneniNonclinical Development, Celgene Corporation, Summit, NJ, USA and
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Pages 43-53 | Received 23 Oct 2017, Accepted 03 Dec 2017, Published online: 19 Dec 2017

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Zeen Tong, Rangaraj Narayanan, Christian Atsriku, Jim Nissel, Yan Li, Hong Liu, Xiaomin Wang & Sekhar Surapaneni. (2019) Assessment of drug–drug interaction potential and PBPK modeling of CC-223, a potent inhibitor of the mammalian target of rapamycin kinase. Xenobiotica 49:1, pages 54-70.
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Articles from other publishers (1)

Simon G. Wong & Shuguang Ma. 2023. Overcoming Obstacles in Drug Discovery and Development. Overcoming Obstacles in Drug Discovery and Development 137 174 .

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