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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 1
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General Xenobiochemistry

Metabolic profile elucidation of Zhi–Zi–Da–Huang decoction in rat intestinal bacteria using high-resolution mass spectrometry combined with multiple analytical perspectives

Miao WangDepartment of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China,
,
Qing HuDepartment of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China,
,
Qingshui ShiJiangsu Institute for Food and Drug Control, Nanjing, China, and
,
Gongjun YangKey Laboratory of Drug Quality Control and Pharmacovigilance, China Pharmaceutical University, Ministry of Education, Nanjing, ChinaCorrespondence[email protected]
&
Fang FengDepartment of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, China, ;Key Laboratory of Drug Quality Control and Pharmacovigilance, China Pharmaceutical University, Ministry of Education, Nanjing, ChinaCorrespondence[email protected]
Pages 1-12 | Received 29 Oct 2017, Accepted 05 Dec 2017, Published online: 22 Dec 2017

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Xiao Chen, Dong-Dong Wang, Hong Xu & Zhi-Ping Li. (2020) Optimization of initial dosing scheme of tacrolimus in pediatric refractory nephrotic syndrome patients based on CYP3A5 genotype and coadministration with wuzhi-capsule. Xenobiotica 50:5, pages 606-613.
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Dong-Dong Wang, Qiao-Feng Ye, Xiao Chen, Hong Xu & Zhi-Ping Li. (2020) Population pharmacokinetics and initial dosing regimen optimization of cyclosporin in pediatric hemophagocytic lymphohistiocytosis patients. Xenobiotica 50:4, pages 435-441.
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Qing Hu, Xixi Li, Qingshui Shi, Gongjun Yang & Fang Feng. (2019) Deciphering the absorption profile and interaction of multi-components of Zhi-Zi-Da-Huang decoction based on in vitro–in silico–in vivo integrated strategy. Xenobiotica 49:7, pages 762-777.
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Articles from other publishers (5)

Xiao Chen, Dongdong Wang, Hong Xu & Zhiping Li. (2019) Initial dose optimization of tacrolimus for children with systemic lupus erythematosus based on the CYP3A5 polymorphism and coadministration with Wuzhi capsule . Journal of Clinical Pharmacy and Therapeutics 45:2, pages 309-317.
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Xiaojun Cai, Ruidong Li, Changcheng Sheng, Yifeng Tao, Quanbao Zhang, Xiaofei Zhang, Juan Li, Conghuan Shen, Xiaoyan Qiu, Zhengxin Wang & Zheng Jiao. (2020) Systematic external evaluation of published population pharmacokinetic models for tacrolimus in adult liver transplant recipients. European Journal of Pharmaceutical Sciences 145, pages 105237.
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Danica Michaličková, Pavel Jansa, Miroslava Bursová, Tomáš Hložek, Radomír Čabala, Jan Miroslav Hartinger, David Ambrož, Michael Aschermann, Jaroslav Lindner, Aleš Linhart, Ondřej Slanař & Elke H.J. Krekels. (2020) Population pharmacokinetics of riociguat and its metabolite in patients with chronic thromboembolic pulmonary hypertension from routine clinical practice. Pulmonary Circulation 10:1, pages 1-11.
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Kaiwen Luo & Yadong Xing. (2019) Metabolic profile analysis of Zhi-zi-chi decoction in feces of normal and chronic unpredictable mild stress-induced depression rats based on UHPLC-ESI-Q-TOF-MS/MS and multiple analytical strategies . RSC Advances 9:68, pages 40037-40050.
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Dongdong Wang, Xiao Chen, Meng Fu, Hong Xu & Zhiping Li. (2019) Tacrolimus increases the expression level of the chemokine receptor CXCR2 to promote renal fibrosis progression. International Journal of Molecular Medicine.
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