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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 3
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General Xenobiochemistry

Identification of UGTs and BCRP as potential pharmacokinetic determinants of the natural flavonoid alpinetin

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Pages 276-283 | Received 15 Jan 2018, Accepted 11 Feb 2018, Published online: 27 Feb 2018

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Yang Li, Jinjin Xu, Chunxia Xu, Zifei Qin, Shishi Li, Liufang Hu, Zhihong Yao, Frank J. Gonzalez & Xinsheng Yao. (2020) Metabolism and disposition of corylifol A from Psoralea corylifolia: metabolite mapping, isozyme contribution, species differences and identification of efflux transporters for corylifol A-O-glucuronide in HeLa1A1 cells. Xenobiotica 50:8, pages 997-1008.
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Dhirendra Singh & Randhir Singh. (2023) Exploration of Pharmacological Potential of Alpinetin. Current Nutrition & Food Science 19:3, pages 238-245.
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Sameena Gul, Muhammad Faisal Maqbool, Dongying Zheng, Yongming Li, Muhammad Khan & Tonghui Ma. (2022) Alpinetin: a Dietary Flavonoid with Diverse Anticancer Effects. Applied Biochemistry and Biotechnology 194:9, pages 4220-4243.
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Ge Zhao, Yue Tong, Fei Luan, Wenjing Zhu, Chenglin Zhan, Tiantian Qin, Weixiao An & Nan Zeng. (2022) Alpinetin: A Review of Its Pharmacology and Pharmacokinetics. Frontiers in Pharmacology 13.
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Yuhua Li, Qiang Meng, Mengbi Yang, Dongyang Liu, Xiangyu Hou, Lan Tang, Xin Wang, Yuanfeng Lyu, Xiaoyan Chen, Kexin Liu, Ai-Ming Yu, Zhong Zuo & Huichang Bi. (2019) Current trends in drug metabolism and pharmacokinetics. Acta Pharmaceutica Sinica B 9:6, pages 1113-1144.
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Jieying Qiu, Hongyu Wu, Feng Feng, Xiaoying He, Caihong Wang, Shenghui Chu & Zheng Xiang. (2019) Metabolic Profiling of Alpinetin in Rat Plasma, Urine, Bile and Feces after Intragastric Administration. Molecules 24:19, pages 3458.
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Tong Liu, Xiaojing Zhang, Yidan Zhang, Jiuzhou Hou, Dong Fang, Hua Sun, Qin Li & Songqiang Xie. (2018) Sulfation disposition of liquiritigenin in SULT1A3 overexpressing HEK293 cells: The role of breast cancer resistance protein (BCRP) and multidrug resistance-associated protein 4 (MRP4) in sulfate efflux of liquiritigenin. European Journal of Pharmaceutical Sciences 124, pages 228-239.
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