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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 6
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General Xenobiochemistry

A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice

Yi-Kun WangState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China; ;University of Chinese Academy of Sciences, Beijing, China; View further author information
,
Xiao-Nan YangState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China; View further author information
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Wei-Qing LiangCenter for Medicinal Resources Research, Zhejiang Academy of Traditional Chinese Medicine, Hangzhou, China; View further author information
,
Yao XiaoState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China; ;University of Chinese Academy of Sciences, Beijing, China; View further author information
,
Qi ZhaoState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China; ;University of Chinese Academy of Sciences, Beijing, China; View further author information
,
Xue-Rong XiaoState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China; View further author information
,
Frank J. GonzalezLaboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USAView further author information
&
Fei LiState Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China; Correspondence[email protected]
View further author information
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Pages 655-670 | Received 16 May 2018, Accepted 11 Jun 2018, Published online: 23 Jul 2018

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Wan Peng, Man-Yun Dai, Li-Juan Bao, Wei-Feng Zhu & Fei Li. (2021) FXR activation prevents liver injury induced by Tripterygium wilfordii preparations. Xenobiotica 51:6, pages 716-727.
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Qiang Shi, Xi Yang, Lijun Ren & William B. Mattes. (2020) Recent advances in understanding the hepatotoxicity associated with protein kinase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 16:3, pages 217-226.
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Miaomiao Tang, Zhanxuan E. Wu & Fei Li. (2024) Integrating network pharmacology and drug side-effect data to explore mechanism of liver injury-induced by tyrosine kinase inhibitors. Computers in Biology and Medicine 170, pages 108040.
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Xuerong Xiao, Ting Zhang, Jianfeng Huang, Qi Zhao & Fei Li. (2020) Effect of CYP3A4 on liver injury induced by triptolide. Biomedical Chromatography 34:8.
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Anne-Laure Clairet, Marie Boiteux-Jurain, Elsa Curtit, Marie Jeannin, Blandine Gérard, Virginie Nerich & Samuel Limat. (2019) Interaction between phytotherapy and oral anticancer agents: prospective study and literature review. Medical Oncology 36:5.
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