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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 9
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Clinical Pharmacokinetics and Metabolism

Absorption, disposition and metabolic pathway of amiselimod (MT-1303) in healthy volunteers in a mass balance study

Takayuki KifujiData Science Department, Ikuyaku. Integrated Value Development Division, Mitsubishi Tanabe Pharma Corporation, Chuo-ku, Tokyo, Japan; Correspondence[email protected]
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,
Shinsuke InoueData Science Department, Ikuyaku. Integrated Value Development Division, Mitsubishi Tanabe Pharma Corporation, Chuo-ku, Tokyo, Japan; View further author information
,
Megumi FurukawaData Science Department, Ikuyaku. Integrated Value Development Division, Mitsubishi Tanabe Pharma Corporation, Chuo-ku, Tokyo, Japan; View further author information
,
Begonya Perez MaderaMitsubishi Tanabe Pharma Europe Ltd., London, UK; View further author information
,
Takahiro GotoDMPK Research Laboratories, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Kanagawa, Japan; View further author information
,
Hiroshi KumagaiDMPK Research Laboratories, Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Kanagawa, Japan; View further author information
,
Stuart J MairQuotient Sciences, Nottingham, UK View further author information
&
Atsuhiro KawaguchiData Science Department, Ikuyaku. Integrated Value Development Division, Mitsubishi Tanabe Pharma Corporation, Chuo-ku, Tokyo, Japan; View further author information
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Pages 1033-1043 | Received 15 May 2018, Accepted 14 Sep 2018, Published online: 21 Dec 2018

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Marie-Laure Boof, Jan Jaap van Lier, Stephen English, Hartmut Fischer, Mike Ufer & Jasper Dingemanse. (2020) Absorption, distribution, metabolism, and excretion of cenerimod, a selective S1P1 receptor modulator in healthy subjects. Xenobiotica 50:8, pages 947-956.
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Articles from other publishers (5)

Jimin Lee, Robert Lester, Terry O'Reilly, Ezra R. Lowe, Neal E. Slatkin, Howard Franklin & Robert J. Israel. (2023) A Randomized, Double‐Blind, Parallel Design Thorough QT Study With a Nested Crossover to Compare the Cardiac Safety of Amiselimod With Placebo and Positive Control in Healthy Volunteers. Clinical Pharmacology in Drug Development.
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Simon G. Wong & Shuguang Ma. 2023. Overcoming Obstacles in Drug Discovery and Development. Overcoming Obstacles in Drug Discovery and Development 137 174 .
Bram Verstockt, Stefania Vetrano, Azucena Salas, Shadi Nayeri, Marjolijn Duijvestein, Niels Vande Casteele, Silvio Danese, Geert D’Haens, Lars Eckmann, William A. Faubion, Brian G. Feagan, Vipul Jairath, Christopher Ma, Dermot McGovern, Julian Panes, William J. Sandborn, Mark S. Silverberg & Severine Vermeire. (2022) Sphingosine 1-phosphate modulation and immune cell trafficking in inflammatory bowel disease. Nature Reviews Gastroenterology & Hepatology 19:6, pages 351-366.
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Jie Wang, Idan Goren, Bo Yang, Sinan Lin, Jiannan Li, Michael Elias, Claudio Fiocchi & Florian Rieder. (2021) Review article: the sphingosine 1 phosphate/sphingosine 1 phosphate receptor axis ‐ a unique therapeutic target in inflammatory bowel disease. Alimentary Pharmacology & Therapeutics 55:3, pages 277-291.
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Alessandra Roggeri, Melissa Schepers, Assia Tiane, Ben Rombaut, Lieve van Veggel, Niels Hellings, Jos Prickaerts, Anna Pittaluga & Tim Vanmierlo. (2020) Sphingosine-1-Phosphate Receptor Modulators and Oligodendroglial Cells: Beyond Immunomodulation. International Journal of Molecular Sciences 21:20, pages 7537.
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